| IL15 enhances CAR-T cell antitumor activity by reducing mTORC1 activity and preserving their stem cell memory phenotype D Alizadeh, RA Wong, X Yang, D Wang, JR Pecoraro, CF Kuo, B Aguilar, ... Cancer immunology research 7 (5), 759-772, 2019 | 363 | 2019 |
| Phase 1 studies of central memory–derived CD19 CAR T–cell therapy following autologous HSCT in patients with B-cell NHL X Wang, LL Popplewell, JR Wagner, A Naranjo, MS Blanchard, MR Mott, ... Blood, The Journal of the American Society of Hematology 127 (24), 2980-2990, 2016 | 344 | 2016 |
| Chimeric antigen receptors with mutated IgG4 Fc spacer avoid fc receptor binding and improve T cell persistence and antitumor efficacy M Jonnalagadda, A Mardiros, R Urak, X Wang, LJ Hoffman, A Bernanke, ... Molecular Therapy 23 (4), 757-768, 2015 | 231 | 2015 |
| Lenalidomide enhances the function of CS1 chimeric antigen receptor–redirected T cells against multiple myeloma X Wang, M Walter, R Urak, L Weng, C Huynh, L Lim, CLW Wong, ... Clinical Cancer Research 24 (1), 106-119, 2018 | 177 | 2018 |
| Co-stimulatory signaling determines tumor antigen sensitivity and persistence of CAR T cells targeting PSCA+ metastatic prostate cancer SJ Priceman, EA Gerdts, D Tilakawardane, KT Kennewick, JP Murad, ... Oncoimmunology 7 (2), e1380764, 2018 | 156 | 2018 |
| Ex vivo Akt inhibition promotes the generation of potent CD19CAR T cells for adoptive immunotherapy R Urak, M Walter, L Lim, CLW Wong, LE Budde, S Thomas, SJ Forman, ... Journal for immunotherapy of cancer 5, 1-13, 2017 | 110 | 2017 |
| IL15 enhances CAR-T cell antitumor activity by reducing mTORC1 activity and preserving their stem cell memory phenotype. Cancer Immunol. Res. 2019; 7: 759–772. doi: 10.1158 … D Alizadeh, RA Wong, X Yang, D Wang, JR Pecoraro, CF Kuo, B Aguilar, ... CIR-18-0466.[Europe PMC free article][Abstract][CrossRef][Google Scholar], 0 | 70 | |
| CMVpp65 vaccine enhances the antitumor efficacy of adoptively transferred CD19-redirected CMV-specific T cells X Wang, CLW Wong, R Urak, A Mardiros, LE Budde, WC Chang, ... Clinical Cancer Research 21 (13), 2993-3002, 2015 | 68 | 2015 |
| Improved Cas9 activity by specific modifications of the tracrRNA T Scott, R Urak, C Soemardy, KV Morris Scientific Reports 9 (1), 16104, 2019 | 40 | 2019 |
| Targeted activation of cystic fibrosis transmembrane conductance regulator O Villamizar, SA Waters, T Scott, S Saayman, N Grepo, R Urak, A Davis, ... Molecular Therapy 27 (10), 1737-1748, 2019 | 36 | 2019 |
| Comparison of naïve and central memory derived CD8+ effector cell engraftment fitness and function following adoptive transfer X Wang, CLW Wong, R Urak, E Taus, B Aguilar, WC Chang, A Mardiros, ... Oncoimmunology 5 (1), e1072671, 2016 | 35 | 2016 |
| The cerebroventricular environment modifies CAR T cells for potent activity against both central nervous system and systemic lymphoma X Wang, C Huynh, R Urak, L Weng, M Walter, L Lim, V Vyas, WC Chang, ... Cancer immunology research 9 (1), 75-88, 2021 | 34 | 2021 |
| Genetic Structure of the Rice Blast Pathogen (Magnaporthe oryzae) over a Decade in North Central California Rice Fields D Pagliaccia, RZ Urak, F Wong, LAI Douhan, CA Greer, G Vidalakis, ... Microbial ecology 75, 310-317, 2018 | 32 | 2018 |
| Preclinical data support leveraging CS1 chimeric antigen receptor T-cell therapy for systemic light chain amyloidosis M Rosenzweig, R Urak, M Walter, L Lim, JF Sanchez, A Krishnan, ... Cytotherapy 19 (7), 861-866, 2017 | 30 | 2017 |
| Regulation of miR-34b/c-targeted gene expression program by SUMOylation YJ Li, L Du, G Aldana-Masangkay, X Wang, R Urak, SJ Forman, ... Nucleic acids research 46 (14), 7108-7123, 2018 | 24 | 2018 |
| Corrosion behaviour and biocompatibility of boron containing titanium alloys in simulated physiological environments V Ravi, A Schissler, W Chantrjaroen, C Beecher, A Razzak, R Urak, ... Corrosion engineering, science and technology 47 (5), 383-387, 2012 | 18 | 2012 |
| Large-scale manufacturing and characterization of CMV-CD19CAR T cells X Wang, R Urak, M Walter, M Guan, T Han, V Vyas, SH Chien, B Gittins, ... Journal for Immunotherapy of Cancer 10 (1), 2022 | 15 | 2022 |
| Single-cell analysis by mass cytometry reveals CD19 CAR T cell spatiotemporal plasticity in patients L Goldberg, ER Haas, V Vyas, R Urak, SJ Forman, X Wang Oncoimmunology 11 (1), 2040772, 2022 | 13 | 2022 |
| Pre-clinical data supporting immunotherapy for HIV using CMV-HIV-specific CAR T cells with CMV vaccine M Guan, L Lim, L Holguin, T Han, V Vyas, R Urak, A Miller, DL Browning, ... Molecular Therapy-Methods & Clinical Development 25, 344-359, 2022 | 11 | 2022 |
| IL-15-mediated reduction of mTORC1 activity preserves the stem cell memory phenotype of CAR-T cells and confers superior antitumor activity D Alizadeh, RA Wong, X Yang, D Wang, JR Pecoraro, CF Kuo, B Aguilar, ... Cancer Immunol Res 7 (5), 2019 | 9 | 2019 |
