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Katherine Hurley
Katherine Hurley
Postdoctoral Researcher, ETH Zürich
在 hest.ethz.ch 的电子邮件经过验证
标题
引用次数
引用次数
年份
Facile Chemoenzymatic Strategies for the Synthesis and Utilization of S‐Adenosyl‐L‐Methionine Analogues
S Singh, J Zhang, TD Huber, M Sunkara, K Hurley, RD Goff, G Wang, ...
Angewandte Chemie International Edition 53 (15), 3965-3969, 2014
1522014
Targeting the bacterial division protein FtsZ
KA Hurley, TMA Santos, GM Nepomuceno, V Huynh, JT Shaw, DB Weibel
Journal of medicinal chemistry 59 (15), 6975-6998, 2016
1332016
Understanding molecular recognition of promiscuity of thermophilic methionine adenosyltransferase sMAT from Sulfolobus solfataricus
F Wang, S Singh, J Zhang, TD Huber, KE Helmich, M Sunkara, KA Hurley, ...
The FEBS journal 281 (18), 4224-4239, 2014
512014
Synthesis of a γ-Lactam Library via Formal Cycloaddition of Imines and Substituted Succinic Anhydrides
DQ Tan, AL Atherton, AJ Smith, C Soldi, KA Hurley, JC Fettinger, JT Shaw
ACS Combinatorial Science 14 (3), 218-223, 2012
472012
Gyramides prevent bacterial growth by inhibiting DNA gyrase and altering chromosome topology
M Rajendram, KA Hurley, MH Foss, KM Thornton, JT Moore, JT Shaw, ...
ACS chemical biology 9 (6), 1312-1319, 2014
462014
N-Benzyl-3-sulfonamidopyrrolidines Are a New Class of Bacterial DNA Gyrase Inhibitors
MH Foss, KA Hurley, NA Sorto, LL Lackner, KM Thornton, JT Shaw, ...
ACS medicinal chemistry letters 2 (4), 289-292, 2011
252011
Membrane-targeting DCAP analogues with broad-spectrum antibiotic activity against pathogenic bacteria
KA Hurley, VA Heinrich, JR Hershfield, ST Demons, DB Weibel
ACS Medicinal Chemistry Letters 6 (4), 466-471, 2015
182015
Impact of manipulation of glycerol/diol dehydratase activity on intestinal microbiota ecology and metabolism
A Ramirez Garcia, J Zhang, A Greppi, F Constancias, E Wortmann, ...
Environmental microbiology 23 (3), 1765-1779, 2021
132021
Targeting quinolone-and aminocoumarin-resistant bacteria with new gyramide analogs that inhibit DNA gyrase
KA Hurley, TMA Santos, MR Fensterwald, M Rajendran, JT Moore, ...
MedChemComm 8 (5), 942-951, 2017
92017
Pathogenic and commensal gut bacteria harboring Glycerol/Diol dehydratase metabolize glycerol and produce DNA-reactive Acrolein
A Ramirez Garcia, K Hurley, G Marastoni, M Diard, S Hofer, A Greppi, ...
Chemical research in toxicology 35 (10), 1840-1850, 2022
82022
5-Alkyloxytryptamines are membrane-targeting, broad-spectrum antibiotics
KC Faulkner, KA Hurley, DB Weibel
Bioorganic & medicinal chemistry letters 26 (22), 5539-5544, 2016
82016
DCAP: A Broad‐spectrum Antibiotic that Targets the Cytoplasmic Membrane of Bacteria
V Heinrich, K Hurley, T Santos, D Weibel
The FASEB Journal 29, 575.6, 2015
42015
Anaerobutyricum hallii promotes the functional depletion of a food carcinogen in diverse healthy fecal microbiota
A Ramirez Garcia, A Greppi, F Constancias, HJ Ruscheweyh, J Gasser, ...
Frontiers in Microbiomes 2, 1194516, 2023
32023
Antimicrobial compounds, compositions and methods of use thereof
DB Weibel, KA Hurley, KC Faulkner
US Patent 9,440,920, 2016
12016
Enzymatic Acrolein Production System and Its Impact on Human Cells
KA Hurley, J Folz, J Zgraggen, TN Cruz, S Diedrich, SJ Sturla
Chemical Research in Toxicology 37 (8), 1374-1381, 2024
2024
Dual DNA and DNA repair protein damage by acrolein in colon epithelial cells
T Cruz, KA Hurley, J Zgraggen, S Diedrich, SJ Sturla
Toxicology Letters 350, S233, 2021
2021
Chemical metabolism and toxicological relevance of microbial glycerol dehydratase from human gut microbiota
J Zhang, K Hurley, A Ramirez, C Lacroix, C Schwab, S Sturla
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 258, 2019
2019
Endogenous microbial generation of acrolein: Strategies to assess the effects of intestinal acrolein formation
K Hurley, A Ramirez-Garcia, S Diedrich, J Zhang, C Lacroix, E Slack, ...
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 258, 2019
2019
Antimicrobial compounds, compositions and methods of use thereof
DB Weibel, YJ Eun, MH Foss, KA Hurley
US Patent 10,314,816, 2019
2019
Human gut microbial glycerol dehydratase function: impact on chemical metabolism and toxicological relevance
S Sturla, J Zhang, K Hurley, MT Empl, M Schneider, G Breves, ...
2019
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