| Hot spots—A review of the protein–protein interface determinant amino‐acid residues IS Moreira, PA Fernandes, MJ Ramos Proteins: Structure, Function, and Bioinformatics 68 (4), 803-812, 2007 | 925 | 2007 |
| Allosteric communication between protomers of dopamine class A GPCR dimers modulates activation Y Han, IS Moreira, E Urizar, H Weinstein, JA Javitch Nature chemical biology 5 (9), 688-695, 2009 | 397 | 2009 |
| Computational alanine scanning mutagenesis—an improved methodological approach IS Moreira, PA Fernandes, MJ Ramos Journal of computational chemistry 28 (3), 644-654, 2007 | 277 | 2007 |
| Vascular endothelial growth factor (VEGF) inhibition-a critical review I Sousa Moreira, P Alexandrino Fernandes, M Joao Ramos Anti-cancer agents in medicinal chemistry (formerly current medicinal …, 2007 | 160 | 2007 |
| Structural features of the G-protein/GPCR interactions IS Moreira Biochimica et Biophysica Acta (BBA) - General Subjects, In press, 2013 | 158 | 2013 |
| Protein–protein docking dealing with the unknown IS Moreira, PA Fernandes, MJ Ramos Journal of computational chemistry 31 (2), 317-342, 2010 | 158 | 2010 |
| Identification of a small-molecule inhibitor of the PICK1 PDZ domain that inhibits hippocampal LTP and LTD TS Thorsen, KL Madsen, N Rebola, M Rathje, V Anggono, A Bach, ... Proceedings of the National Academy of Sciences 107 (1), 413-418, 2010 | 140 | 2010 |
| Membrane proteins structures: A review on computational modeling tools JG Almeida, AJ Preto, PI Koukos, AMJJ Bonvin, IS Moreira Biochimica et Biophysica Acta (BBA)-Biomembranes 1859 (10), 2021-2039, 2017 | 118 | 2017 |
| Performance of HADDOCK and a simple contact-based protein–ligand binding affinity predictor in the D3R Grand Challenge 2 Z Kurkcuoglu, PI Koukos, N Citro, ME Trellet, J Rodrigues, IS Moreira, ... Journal of computer-aided molecular design 32, 175-185, 2018 | 117 | 2018 |
| SpotOn: high accuracy identification of protein-protein interface hot-spots IS Moreira, PI Koukos, R Melo, JG Almeida, AJ Preto, J Schaarschmidt, ... Scientific reports 7 (1), 8007, 2017 | 94 | 2017 |
| Unraveling the Importance of Protein− Protein Interaction: Application of a Computational Alanine-Scanning Mutagenesis to the Study of the IgG1 Streptococcal Protein G (C2 … IS Moreira, PA Fernandes, MJ Ramos The Journal of Physical Chemistry B 110 (22), 10962-10969, 2006 | 89 | 2006 |
| Computational Alanine Scanning Mutagenesis: MMPBSA vs TI SA Martins, MAS Perez, IS Moreira, SF Sousa, MJ Ramos, PA Fernandes Journal of Chemical Theory and Computation, 2013 | 75 | 2013 |
| Evolution of drug resistance: insight on TEM β-lactamases structure and activity and β-lactam antibiotics AC Pimenta, R Fernandes, IS Moreira Mini reviews in medicinal chemistry 14 (2), 111-122, 2014 | 63 | 2014 |
| The central role of non-structural protein 1 (NS1) in influenza biology and infection N Rosário-Ferreira, AJ Preto, R Melo, IS Moreira, RMM Brito International Journal of Molecular Sciences 21 (4), 1511, 2020 | 55 | 2020 |
| A machine learning approach for hot-spot detection at protein-protein interfaces R Melo, R Fieldhouse, A Melo, JDG Correia, MNDS Cordeiro, ZH Gümüş, ... International journal of molecular sciences 17 (8), 1215, 2016 | 55 | 2016 |
| Understanding the importance of the aromatic amino-acid residues as hot-spots IS Moreira, JM Martins, RM Ramos, PA Fernandes, MJ Ramos Biochimica et Biophysica Acta (BBA)-Proteins and Proteomics 1834 (1), 404-414, 2013 | 51 | 2013 |
| Hot spot occlusion from bulk water: a comprehensive study of the complex between the lysozyme HEL and the antibody FVD1. 3 IS Moreira, PA Fernandes, MJ Ramos The Journal of Physical Chemistry B 111 (10), 2697-2706, 2007 | 49 | 2007 |
| Unravelling Hot Spots: a comprehensive computational mutagenesis study IS Moreira, PA Fernandes, MJ Ramos Theoretical Chemistry Accounts 117, 99-113, 2007 | 47 | 2007 |
| Structure–activity relationships of a small-molecule inhibitor of the PDZ domain of PICK1 A Bach, N Stuhr-Hansen, TS Thorsen, N Bork, IS Moreira, K Frydenvang, ... Organic & biomolecular chemistry 8 (19), 4281-4288, 2010 | 43 | 2010 |
| SASA-Based Hot-spot Detection 2 (SBHD2) Methods for Protein-Protein and Protein-Nucleic Acid Interfaces. MIS Munteanu C, Pimenta AC, Fernandez-Lozano C, Melo A, Dias Soeiro Cordeiro MN J Chem Inf Model, 2015 | 39* | 2015 |
Pedro A. FernandesProfessor of Chemistry and Biochemistry, University of Porto, Portugal在 fc.up.pt 的电子邮件经过验证
