Wnt-5a/JNK signaling promotes the clustering of PSD-95 in hippocampal neurons GG Farías, IE Alfaro, W Cerpa, CP Grabowski, JA Godoy, C Bonansco, ... Journal of Biological Chemistry 284 (23), 15857-15866, 2009 | 261 | 2009 |
Wnt-7a modulates the synaptic vesicle cycle and synaptic transmission in hippocampal neurons W Cerpa, JA Godoy, I Alfaro, GG Farías, MJ Metcalfe, R Fuentealba, ... Journal of Biological Chemistry 283 (9), 5918-5927, 2008 | 261 | 2008 |
Regulation of NMDA-receptor synaptic transmission by Wnt signaling W Cerpa, A Gambrill, NC Inestrosa, A Barria Journal of Neuroscience 31 (26), 9466-9471, 2011 | 190 | 2011 |
Acetylcholinesterase-Aβ complexes are more toxic than Aβ fibrils in rat hippocampus: effect on rat β-amyloid aggregation, laminin expression, reactive astrocytosis, and … AE Reyes, MA Chacón, MC Dinamarca, W Cerpa, C Morgan, ... The American journal of pathology 164 (6), 2163-2174, 2004 | 181 | 2004 |
Role of NMDA Receptor‐Mediated Glutamatergic Signaling in Chronic and Acute Neuropathologies FJ Carvajal, HA Mattison, W Cerpa Neural plasticity 2016 (1), 2701526, 2016 | 155 | 2016 |
Wnt-5aoccludes Aβ oligomer-induced depression of glutamatergic transmission in hippocampal neurons W Cerpa, GG Farías, JA Godoy, M Fuenzalida, C Bonansco, NC Inestrosa Molecular neurodegeneration 5, 1-13, 2010 | 152 | 2010 |
Hyperforin prevents β-amyloid neurotoxicity and spatial memory impairments by disaggregation of Alzheimer's amyloid-β-deposits MC Dinamarca, W Cerpa, J Garrido, JL Hancke, NC Inestrosa Molecular psychiatry 11 (11), 1032-1048, 2006 | 141 | 2006 |
Human-like rodent amyloid-β-peptide determines Alzheimer pathology in aged wild-type Octodon degu NC Inestrosa, AE Reyes, MA Chacón, W Cerpa, A Villalón, J Montiel, ... Neurobiology of aging 26 (7), 1023-1028, 2005 | 141 | 2005 |
Structure-function implications in Alzheimer's disease: effect of Aβ oligomers at central synapses W Cerpa, MC Dinamarca, NC Inestrosa Current Alzheimer Research 5 (3), 233-243, 2008 | 122 | 2008 |
Andrographolide reduces cognitive impairment in young and mature AβPPswe/PS-1 mice FG Serrano, C Tapia-Rojas, FJ Carvajal, J Hancke, W Cerpa, ... Molecular Neurodegeneration 9, 1-18, 2014 | 115 | 2014 |
Traumatic brain injury: mechanisms of glial response RG Mira, M Lira, W Cerpa Frontiers in physiology 12, 740939, 2021 | 108 | 2021 |
Is there a role for copper in neurodegenerative diseases? W Cerpa, L Varela-Nallar, AE Reyes, AN Minniti, NC Inestrosa Molecular aspects of medicine 26 (4-5), 405-420, 2005 | 98 | 2005 |
Quercetin Exerts Differential Neuroprotective Effects Against H2O2 and Aβ Aggregates in Hippocampal Neurons: the Role of Mitochondria JA Godoy, CB Lindsay, RA Quintanilla, FJ Carvajal, W Cerpa, ... Molecular neurobiology 54, 7116-7128, 2017 | 75 | 2017 |
Genetic ablation of tau improves mitochondrial function and cognitive abilities in the hippocampus C Jara, A Aránguiz, W Cerpa, C Tapia-Rojas, RA Quintanilla Redox Biology 18, 279-294, 2018 | 74 | 2018 |
Amyloid-β peptide fibrils induce nitro-oxidative stress in neuronal cells G Ill-Raga, E Ramos-Fernández, FX Guix, M Tajes, M Bosch-Morató, ... Journal of Alzheimer's Disease 22 (2), 641-652, 2010 | 70 | 2010 |
The role of Wnt signaling in neuroprotection. W Cerpa, EM Toledo, L Varela-Nallar, NC Inestrosa Drug news & perspectives 22 (10), 579-591, 2009 | 70 | 2009 |
Adolescent binge alcohol exposure affects the brain function through mitochondrial impairment C Tapia-Rojas, FJ Carvajal, RG Mira, C Arce, JM Lerma-Cabrera, ... Molecular neurobiology 55 (5), 4473-4491, 2018 | 67 | 2018 |
Amyloid-β oligomers synaptotoxicity: The emerging role of EphA4/c-Abl signaling in Alzheimer's disease LM Vargas, W Cerpa, FJ Muñoz, S Zanlungo, AR Alvarez Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1864 (4 …, 2018 | 61 | 2018 |
Release of acetylcholinesterase (AChE) from β-amyloid plaques assemblies improves the spatial memory impairments in APP-transgenic mice MC Dinamarca, M Arrázola, E Toledo, WF Cerpa, J Hancke, NC Inestrosa Chemico-biological interactions 175 (1-3), 142-149, 2008 | 58 | 2008 |
RoR2 functions as a noncanonical Wnt receptor that regulates NMDAR-mediated synaptic transmission W Cerpa, E Latorre-Esteves, A Barria Proceedings of the National Academy of Sciences 112 (15), 4797-4802, 2015 | 52 | 2015 |