Dystrophin‐deficient mdx mice display a reduced life span and are susceptible to spontaneous rhabdomyosarcoma JS Chamberlain, J Metzger, M Reyes, DW Townsend, JA Faulkner Federation of American Societies for Experimental Biology, 2007 | 399 | 2007 |
Dystrophic heart failure blocked by membrane sealant poloxamer S Yasuda, DW Townsend, DE Michele, EG Favre, SM Day, JM Metzger Nature 436 (7053), 1025-1029, 2005 | 375 | 2005 |
In situ expansion, differentiation, and electromechanical coupling of human cardiac muscle in a 3D bioprinted, chambered organoid ME Kupfer, WH Lin, V Ravikumar, K Qiu, L Wang, L Gao, DB Bhuiyan, ... Circulation research 127 (2), 207-224, 2020 | 247 | 2020 |
Systemic administration of micro-dystrophin restores cardiac geometry and prevents dobutamine-induced cardiac pump failure DW Townsend, MJ Blankinship, JM Allen, P Gregorevic, JS Chamberlain, ... Molecular Therapy 15 (6), 1086-1092, 2007 | 155 | 2007 |
Chronic administration of membrane sealant prevents severe cardiac injury and ventricular dilatation in dystrophic dogs DW Townsend, I Turner, S Yasuda, J Martindale, J Davis, M Shillingford, ... The Journal of clinical investigation 120 (4), 1140-1150, 2010 | 139 | 2010 |
Emergent dilated cardiomyopathy caused by targeted repair of dystrophic skeletal muscle DW Townsend, S Yasuda, S Li, JS Chamberlain, JM Metzger Molecular therapy 16 (5), 832-835, 2008 | 135 | 2008 |
Cardiac pathophysiology and the future of cardiac therapies in Duchenne muscular dystrophy TA Meyers, DW Townsend International journal of molecular sciences 20 (17), 4098, 2019 | 112 | 2019 |
The veterinary ICU book WE Wingfield, MR Raffe CRC Press, 2020 | 85 | 2020 |
Designing heart performance by gene transfer J Davis, MV Westfall, D Townsend, M Blankinship, TJ Herron, ... Physiological reviews 88 (4), 1567-1651, 2008 | 75 | 2008 |
Distinct pathophysiological mechanisms of cardiomyopathy in hearts lacking dystrophin or the sarcoglycan complex DW Townsend, S Yasuda, E McNally, JM Metzger The FASEB journal 25 (9), 3106, 2011 | 70 | 2011 |
Skeletal muscle glycolytic capacity and phosphofructokinase regulation in horses with polysaccharide storage myopathy SJ Valberg, DW Townsend, JR Mickelson American journal of veterinary research 59 (6), 782-782, 1998 | 68 | 1998 |
Stem cell–derived cardiomyocytes and beta-adrenergic receptor blockade in Duchenne muscular dystrophy cardiomyopathy F Kamdar, S Das, W Gong, A Klaassen Kamdar, TA Meyers, P Shah, ... Journal of the American College of Cardiology 75 (10), 1159-1174, 2020 | 55 | 2020 |
Cardiomyopathy of Duchenne muscular dystrophy: pathogenesis and prospect of membrane sealants as a new therapeutic approach DW Townsend, S Yasuda, J Metzger Expert review of cardiovascular therapy 5 (1), 99-109, 2007 | 52 | 2007 |
Early right ventricular fibrosis and reduction in biventricular cardiac reserve in the dystrophin-deficient mdx heart TA Meyers, DW Townsend American Journal of Physiology-Heart and Circulatory Physiology 308 (4 …, 2015 | 45 | 2015 |
Cardiac consequences to skeletal muscle-centric therapeutics for Duchenne muscular dystrophy DW Townsend, S Yasuda, J Chamberlain, JM Metzger Trends in Cardiovascular Medicine 19 (2), 49-54, 2009 | 43 | 2009 |
CRABP1 protects the heart from isoproterenol-induced acute and chronic remodeling SW Park, SD Persaud, S Ogokeh, TA Meyers, DW Townsend, LN Wei Journal of Endocrinology 236 (3), 151-165, 2018 | 42 | 2018 |
Integrative effects of dystrophin loss on metabolic function of the mdx mouse J Strakova, F Kamdar, D Kulhanek, M Razzoli, DJ Garry, JM Ervasti, ... Scientific reports 8 (1), 13624, 2018 | 37 | 2018 |
Severe dystrophic cardiomyopathy caused by the enteroviral protease 2A–mediated C-terminal dystrophin cleavage fragment MS Barnabei, FV Sjaastad, DW Townsend, FB Bedada, JM Metzger Science Translational Medicine 7 (294), 294ra106-294ra106, 2015 | 34 | 2015 |
Dystrobrevin increases dystrophin's binding to the dystrophin–glycoprotein complex and provides protection during cardiac stress J Strakova, JD Dean, KM Sharpe, TA Meyers, GL Odom, DW Townsend Journal of molecular and cellular cardiology 76, 106-115, 2014 | 34 | 2014 |
Heparan sulfate Ndst1 regulates vascular smooth muscle cell proliferation, vessel size and vascular remodeling N Adhikari, DL Basi, DW Townsend, M Rusch, A Mariash, S Mullegama, ... Journal of Molecular and Cellular Cardiology 49 (2), 287-293, 2010 | 29 | 2010 |