Losing the beat: contribution of Purkinje cell firing dysfunction to disease, and its reversal AA Cook, E Fields, AJ Watt Neuroscience 462, 247-261, 2021 | 67 | 2021 |
Altered synaptic and firing properties of cerebellar Purkinje cells in a mouse model of ARSACS V Ady, B Toscano‐Márquez, M Nath, PK Chang, J Hui, A Cook, F Charron, ... The Journal of physiology 596 (17), 4253-4267, 2018 | 39 | 2018 |
Exploring the significance of morphological diversity for cerebellar granule cell excitability CM Houston, E Diamanti, M Diamantaki, E Kutsarova, A Cook, F Sultan, ... Scientific reports 7 (1), 46147, 2017 | 23 | 2017 |
Activation of TrkB-Akt signaling rescues deficits in a mouse model of SCA6 AA Cook, S Jayabal, J Sheng, E Fields, TCS Leung, S Quilez, ... Science Advances 8 (37), eabh3260, 2022 | 13* | 2022 |
Molecular identity and location influence Purkinje cell vulnerability in autosomal-recessive spastic ataxia of charlevoix-saguenay mice B Toscano Márquez, AA Cook, M Rice, A Smileski, K Vieira-Lomasney, ... Frontiers in Cellular Neuroscience 15, 707857, 2021 | 9 | 2021 |
Endosomal dysfunction contributes to cerebellar deficits in spinocerebellar ataxia type 6 AA Cook, TCS Leung, M Rice, M Nachman, É Zadigue-Dubé, AJ Watt Elife 12, RP90510, 2023 | 5 | 2023 |
Loss of flocculus purkinje cell firing precision leads to impaired gaze stabilization in a mouse model of spinocerebellar ataxia type 6 (SCA6) HHV Chang, AA Cook, AJ Watt, KE Cullen Cells 11 (17), 2739, 2022 | 3 | 2022 |
Mitochondrial damage and impaired mitophagy contribute to disease progression in SCA6 TCS Leung, E Fields, N Rana, RYL Shen, AE Bernstein, AA Cook, ... Acta Neuropathologica 147 (1), 26, 2024 | 2 | 2024 |
Disruption of BDNF-TrkB signaling in spinocerebellar ataxia type 6 A Cook McGill University, 2023 | | 2023 |
ASOs clear toxic protein from cells, reducing ataxia in SCA2 mice A Cook, A Watt, V Bondar | | |