| Disordered lipid metabolism and the pathogenesis of insulin resistance DB Savage, KF Petersen, GI Shulman Physiological reviews 87 (2), 507-520, 2007 | 1403 | 2007 |
| Resistin/Fizz3 expression in relation to obesity and peroxisome proliferator–activated receptor-γ action in humans DB Savage, CP Sewter, ES Klenk, DG Segal, A Vidal-Puig, RV Considine, ... Diabetes 50 (10), 2199-2202, 2001 | 1172 | 2001 |
| A genome-wide approach accounting for body mass index identifies genetic variants influencing fasting glycemic traits and insulin resistance AK Manning, MF Hivert, RA Scott, JL Grimsby, N Bouatia-Naji, H Chen, ... Nature genetics 44 (6), 659-669, 2012 | 922 | 2012 |
| The role of skeletal muscle insulin resistance in the pathogenesis of the metabolic syndrome KF Petersen, S Dufour, DB Savage, S Bilz, G Solomon, S Yonemitsu, ... Proceedings of the National Academy of Sciences 104 (31), 12587-12594, 2007 | 920 | 2007 |
| Induction of adipocyte complement-related protein of 30 kilodaltons by PPARγ agonists: a potential mechanism of insulin sensitization TP Combs, JA Wagner, J Berger, T Doebber, WJ Wang, BB Zhang, ... Endocrinology 143 (3), 998-1007, 2002 | 850 | 2002 |
| Human metabolic syndrome resulting from dominant-negative mutations in the nuclear receptor peroxisome proliferator-activated receptor-γ DB Savage, GD Tan, CL Acerini, SA Jebb, M Agostini, M Gurnell, ... Diabetes 52 (4), 910-917, 2003 | 584 | 2003 |
| Integrative genomic analysis implicates limited peripheral adipose storage capacity in the pathogenesis of human insulin resistance LA Lotta, P Gulati, FR Day, F Payne, H Ongen, M Van De Bunt, ... Nature genetics 49 (1), 17-26, 2017 | 556 | 2017 |
| Reversal of diet-induced hepatic steatosis and hepatic insulin resistance by antisense oligonucleotide inhibitors of acetyl-CoA carboxylases 1 and 2 DB Savage, CS Choi, VT Samuel, ZX Liu, D Zhang, A Wang, XM Zhang, ... The Journal of clinical investigation 116 (3), 817-824, 2006 | 530 | 2006 |
| GDF15 mediates the effects of metformin on body weight and energy balance AP Coll, M Chen, P Taskar, D Rimmington, S Patel, JA Tadross, I Cimino, ... Nature 578 (7795), 444-448, 2020 | 465 | 2020 |
| Mechanisms of insulin resistance in humans and possible links with inflammation DB Savage, KF Petersen, GI Shulman Hypertension 45 (5), 828-833, 2005 | 446 | 2005 |
| Suppression of diacylglycerol acyltransferase-2 (DGAT2), but not DGAT1, with antisense oligonucleotides reverses diet-induced hepatic steatosis and insulin resistance CS Choi, DB Savage, A Kulkarni, XX Yu, ZX Liu, K Morino, S Kim, ... Journal of Biological Chemistry 282 (31), 22678-22688, 2007 | 440 | 2007 |
| Genetic variation near IRS1 associates with reduced adiposity and an impaired metabolic profile TO Kilpeläinen, MC Zillikens, A Stančákova, FM Finucane, JS Ried, ... Nature genetics 43 (8), 753-760, 2011 | 431 | 2011 |
| Genetic predisposition to an impaired metabolism of the branched-chain amino acids and risk of type 2 diabetes: a Mendelian randomisation analysis LA Lotta, RA Scott, SJ Sharp, S Burgess, J Luan, T Tillin, AF Schmidt, ... PLoS medicine 13 (11), e1002179, 2016 | 425 | 2016 |
| Postreceptor insulin resistance contributes to human dyslipidemia and hepatic steatosis RK Semple, A Sleigh, PR Murgatroyd, CA Adams, L Bluck, S Jackson, ... The Journal of clinical investigation 119 (2), 315-322, 2009 | 404 | 2009 |
| Genetic syndromes of severe insulin resistance RK Semple, DB Savage, EK Cochran, P Gorden, S O'Rahilly Endocrine reviews 32 (4), 498-514, 2011 | 402 | 2011 |
| GDF15 provides an endocrine signal of nutritional stress in mice and humans S Patel, A Alvarez-Guaita, A Melvin, D Rimmington, A Dattilo, ... Cell metabolism 29 (3), 707-718. e8, 2019 | 392 | 2019 |
| Association between low-density lipoprotein cholesterol–lowering genetic variants and risk of type 2 diabetes: a meta-analysis LA Lotta, SJ Sharp, S Burgess, JRB Perry, ID Stewart, SM Willems, J Luan, ... Jama 316 (13), 1383-1391, 2016 | 392 | 2016 |
| Continuous fat oxidation in acetyl–CoA carboxylase 2 knockout mice increases total energy expenditure, reduces fat mass, and improves insulin sensitivity CS Choi, DB Savage, L Abu-Elheiga, ZX Liu, S Kim, A Kulkarni, ... Proceedings of the National Academy of Sciences 104 (42), 16480-16485, 2007 | 375 | 2007 |
| Correlation of the leptin: adiponectin ratio with measures of insulin resistance in non-diabetic individuals FM Finucane, J Luan, NJ Wareham, SJ Sharp, S O’rahilly, B Balkau, ... Diabetologia 52, 2345-2349, 2009 | 372 | 2009 |
| Seipin is required for converting nascent to mature lipid droplets H Wang, M Becuwe, BE Housden, C Chitraju, AJ Porras, MM Graham, ... elife 5, e16582, 2016 | 359 | 2016 |
