AGGRESCAN: a server for the prediction and evaluation of" hot spots" of aggregation in polypeptides O Conchillo-Solé, NS de Groot, FX Avilés, J Vendrell, X Daura, S Ventura BMC bioinformatics 8, 1-17, 2007 | 1039 | 2007 |
Design, selection, and characterization of thioflavin-based intercalation compounds with metal chelating properties for application in Alzheimer’s disease C Rodríguez-Rodríguez, N Sanchez de Groot, A Rimola, ... Journal of the American Chemical Society 131 (4), 1436-1451, 2009 | 251 | 2009 |
Amyloid fibril formation by a partially structured intermediate state of α-chymotrypsin I Pallarès, J Vendrell, FX Avilés, S Ventura Journal of molecular biology 342 (1), 321-331, 2004 | 251 | 2004 |
Prediction of" hot spots" of aggregation in disease-linked polypeptides NS De Groot, I Pallarés, FX Avilés, J Vendrell, S Ventura BMC Structural Biology 5, 1-15, 2005 | 238 | 2005 |
Mutagenesis of the central hydrophobic cluster in Aβ42 Alzheimer's peptide: Side‐chain properties correlate with aggregation propensities NS De Groot, FX Aviles, J Vendrell, S Ventura The FEBS journal 273 (3), 658-668, 2006 | 198 | 2006 |
Metallocarboxypeptidases and their protein inhibitors: structure, function and biomedical properties J Vendrell, E Querol, FX Avilés Biochimica et Biophysica Acta (BBA)-Protein Structure and Molecular …, 2000 | 194 | 2000 |
Ile-Phe dipeptide self-assembly: clues to amyloid formation NS De Groot, T Parella, FX Aviles, J Vendrell, S Ventura Biophysical journal 92 (5), 1732-1741, 2007 | 153 | 2007 |
A carboxypeptidase inhibitor from the medical leech Hirudo medicinalis: Isolation, sequence analysis, cDNA cloning, recombinant expression, and characterization D Reverter, J Vendrell, F Canals, J Horstmann, FX Avilés, H Fritz, ... Journal of Biological Chemistry 273 (49), 32927-32933, 1998 | 136 | 1998 |
Metallocarboxypeptidases: emerging drug targets in biomedicine JL Arolas, J Vendrell, FX Aviles, LD Fricker Current pharmaceutical design 13 (4), 349-366, 2007 | 134 | 2007 |
Structure of human carboxypeptidase A4 with its endogenous protein inhibitor, latexin I Pallarès, R Bonet, R García-Castellanos, S Ventura, FX Avilés, ... Proceedings of the National Academy of Sciences 102 (11), 3978-3983, 2005 | 123 | 2005 |
Structure of a novel leech carboxypeptidase inhibitor determined free in solution and in complex with human carboxypeptidase A2 D Reverter, C Fernández-Catalán, R Baumgartner, R Pfänder, R Huber, ... Nature structural biology 7 (4), 322-328, 2000 | 120 | 2000 |
The three‐dimensional structure of human procarboxypeptidase A2. Deciphering the basis of the inhibition, activation and intrinsic activity of the zymogen I García‐Sáez, D Reverter, J Vendrell, FX Avilés, M Coll The EMBO journal, 1997 | 110 | 1997 |
Advances in metallo‐procarboxypeptidases: Emerging details on the inhibition mechanism and on the activation process FX AVILÉS, J VENDRELL, A GUASCH, M COLL, R HUBER European journal of biochemistry 211 (3), 381-389, 1993 | 108 | 1993 |
Complete amino acid analysis of proteins by dabsyl derivatization and reversed-phase liquid chromatogrphy J Vendrell, FX Avilés Journal of Chromatography A 358, 401-413, 1986 | 108 | 1986 |
Identification and characterization of three members of the human metallocarboxypeptidase gene family S Wei, S Segura, J Vendrell, FX Aviles, E Lanoue, R Day, Y Feng, ... Journal of Biological Chemistry 277 (17), 14954-14964, 2002 | 105 | 2002 |
The crystal structure of the inhibitor-complexed carboxypeptidase D domain II and the modeling of regulatory carboxypeptidases P Aloy, V Companys, J Vendrell, FX Aviles, LD Fricker, M Coll, ... Journal of Biological Chemistry 276 (19), 16177-16184, 2001 | 98 | 2001 |
Crystal structure of avian carboxypeptidase D domain II: a prototype for the regulatory metallocarboxypeptidase subfamily FX Gomis-Rüth, V Companys, Y Qian, LD Fricker, J Vendrell, FX Avilés, ... The EMBO journal 18 (21), 5817-5826, 1999 | 90 | 1999 |
Human procarboxypeptidase B: three-dimensional structure and implications for thrombin-activatable fibrinolysis inhibitor (TAFI) PJB Pereira, S Segura-Martın, B Oliva, C Ferrer-Orta, FX Aviles, M Coll, ... Journal of molecular biology 321 (3), 537-547, 2002 | 89 | 2002 |
Structural basis of the resistance of an insect carboxypeptidase to plant protease inhibitors A Bayés, M Comellas-Bigler, MR De La Vega, K Maskos, W Bode, ... Proceedings of the National Academy of Sciences 102 (46), 16602-16607, 2005 | 85 | 2005 |
Human kallikrein 6 activity is regulated via an autoproteolytic mechanism of activation/inactivation A Bayes, T Tsetsenis, S Ventura, J Vendrell, FX Aviles, G Sotiropoulou Walter de Gruyter 385 (6), 517-524, 2004 | 85 | 2004 |