| Comparison of polysorbate 80 hydrolysis and oxidation on the aggregation of a monoclonal antibody NR Larson, Y Wei, I Prajapati, A Chakraborty, B Peters, C Kalonia, ... Journal of Pharmaceutical Sciences 109 (1), 633-639, 2020 | 74 | 2020 |
| Glatiramer acetate persists at the injection site and draining lymph nodes via electrostatically-induced aggregation JY Song, NR Larson, S Thati, I Torres-Vazquez, N Martinez-Rivera, ... Journal of controlled release 293, 36-47, 2019 | 29 | 2019 |
| Molecular trajectories provide signatures of protein clustering and crowding at the oil/water interface AC McUmber, NR Larson, TW Randolph, DK Schwartz Langmuir 31 (21), 5882-5890, 2015 | 23 | 2015 |
| Improved fluorescence methods for high-throughput protein formulation screening Y Wei, NR Larson, SK Angalakurthi, C Russell Middaugh SLAS Technology: Translating Life Sciences Innovation 23 (6), 516-528, 2018 | 22 | 2018 |
| Optimization of RG1-VLP vaccine performance in mice with novel TLR4 agonists A Zacharia, E Harberts, SM Valencia, B Myers, C Sanders, A Jain, ... Vaccine 39 (2), 292-302, 2021 | 20 | 2021 |
| Soluble antigen arrays for selective desensitization of insulin-reactive B cells MA Leon, SM Wemlinger, NR Larson, JK Ruffalo, JO Sestak, ... Molecular pharmaceutics 16 (4), 1563-1572, 2019 | 20 | 2019 |
| pH-dependent phase behavior and stability of cationic lipid–mRNA nanoparticles NR Larson, G Hu, Y Wei, AD Tuesca, ML Forrest, CR Middaugh Journal of Pharmaceutical Sciences 111 (3), 690-698, 2022 | 17 | 2022 |
| Cis/trans isomerization of unsaturated fatty acids in polysorbate 80 during light exposure of a monoclonal antibody–containing formulation I Prajapati, BH Peters, NR Larson, Y Wei, S Choudhary, C Kalonia, ... Journal of Pharmaceutical Sciences 109 (1), 603-613, 2020 | 16 | 2020 |
| Label-free, direct measurement of protein concentrations in turbid solutions with a UV–visible integrating cavity absorbance spectrometer NR Larson, Y Wei, CR Middaugh Analytical chemistry 90 (8), 4982-4986, 2018 | 15 | 2018 |
| Effect of 2 emulsion-based adjuvants on the structure and thermal stability of staphylococcus aureus alpha-toxin Y Wei, J Xiong, NR Larson, V Iyer, G Sanyal, SB Joshi, DB Volkin, ... Journal of pharmaceutical sciences 107 (9), 2325-2334, 2018 | 12 | 2018 |
| Effects of glycan structure on the stability and receptor binding of an IgG4-Fc H Kang, NR Larson, DR White, CR Middaugh, T Tolbert, C Schöneich Journal of Pharmaceutical Sciences 109 (1), 677-689, 2020 | 9 | 2020 |
| ACUVRA: Anion-Exchange Chromatography UV-Ratio Analysis—A QC-Friendly Method for Monitoring Adeno-Associated Virus Empty Capsid Content to Support Process Development and GMP … R Frenkel, D Tribby, B Boumajny, N Larson, M Sampson, C Barney, ... The AAPS Journal 25 (1), 3, 2022 | 4 | 2022 |
| Rapid high-resolution size distribution protocol for adeno-associated virus using high speed SV-AUC SA Berkowitz, N Larson, G Bou-Assaf, T Laue Analytical Biochemistry 689, 115482, 2024 | 3 | 2024 |
| Synthetic Cationic Autoantigen Mimics Glatiramer Acetate Persistence at the Site of Injection and Is Efficacious Against Experimental Autoimmune Encephalomyelitis JY Song, JD Griffin, NR Larson, MA Christopher, CR Middaugh, ... Frontiers in Immunology 11, 603029, 2021 | 3 | 2021 |
| Conformational changes and drivers of monoclonal antibody liquid-liquid phase separation NR Larson, Y Wei, TA Cruz, R Esfandiary, CK Kalonia, ML Forrest, ... Journal of pharmaceutical sciences 112 (3), 680-690, 2023 | 2 | 2023 |
| Visible Light Degradation of a Monoclonal Antibody in a High-Concentration Formulation: Characterization of a Tryptophan-Derived Chromophoric Photo-product by Comparison to … I Prajapati, NR Larson, S Choudhary, C Kalonia, S Hudak, R Esfandiary, ... Molecular Pharmaceutics 18 (9), 3223-3234, 2021 | 2 | 2021 |
| Chapter 7: An Empirical Phase Diagram: High-Throughput Screening Approach to the Characterization and Formulation of Biopharmaceuticals Y Wei, SB Joshi, A Bhambhani, Y Zeng, NR Larson, G Hu, EJ Deeds, ... Development of Biopharmaceutical Drug-Device Products, 139-185, 2020 | 2 | 2020 |
| Development of UPLC-UV-ELSD Method for Fatty Acid Profiling in Polysorbate 80 and Confirmation of the Presence of Conjugated Fatty Acids by Mass Spectrometry, UV Absorbance and … M Doyle, A Barnes, NR Larson, H Liu, L Yi Journal of Pharmaceutical Sciences 112 (9), 2393-2403, 2023 | 1 | 2023 |
| Establishing stereochemical comparability in phosphorothioate oligonucleotides with nuclease P1 digestion coupled with LCMS analysis Z Li, F Tong, L Xiao, NR Larson, X Zhou, Y Zhang, JP Immel-Brown, ... Analyst 148 (21), 5361-5365, 2023 | 1 | 2023 |
| Subunit-based vaccines: challenges in developing protein-based vaccines SF Ausar, NR Larson, Y Wei, A Jain, CR Middaugh Practical Aspects of Vaccine Development, 79-135, 2022 | 1 | 2022 |
