The tripartite motif family identifies cell compartments A Reymond, G Meroni, A Fantozzi, G Merla, S Cairo, L Luzi, D Riganelli, ... The EMBO journal, 2001 | 1605 | 2001 |
Electron transfer between cytochrome c and p66Shc generates reactive oxygen species that trigger mitochondrial apoptosis M Giorgio, E Migliaccio, F Orsini, D Paolucci, M Moroni, C Contursi, ... Cell 122 (2), 221-233, 2005 | 1317 | 2005 |
Myc-binding-site recognition in the human genome is determined by chromatin context E Guccione, F Martinato, G Finocchiaro, L Luzi, L Tizzoni, V Dall'Olio, ... Nature cell biology 8 (7), 764-770, 2006 | 431 | 2006 |
Acute myeloid leukemia bearing cytoplasmic nucleophosmin (NPMc+ AML) shows a distinct gene expression profile characterized by up-regulation of genes … M Alcalay, E Tiacci, R Bergomas, B Bigerna, E Venturini, SP Minardi, ... Blood 106 (3), 899-902, 2005 | 418 | 2005 |
Complex loci in human and mouse genomes PG Engström, H Suzuki, N Ninomiya, A Akalin, L Sessa, G Lavorgna, ... PLoS genetics 2 (4), e47, 2006 | 354 | 2006 |
Acute myeloid leukemia fusion proteins deregulate genes involved in stem cell maintenance and DNA repair M Alcalay, N Meani, V Gelmetti, A Fantozzi, M Fagioli, A Orleth, ... The Journal of clinical investigation 112 (11), 1751-1761, 2003 | 334 | 2003 |
Evolution of Shc functions from nematode to human L Luzi, S Confalonieri, PP Di Fiore, PG Pelicci Current opinion in genetics & development 10 (6), 668-674, 2000 | 283 | 2000 |
Immunohistochemistry predicts nucleophosmin (NPM) mutations in acute myeloid leukemia B Falini, MP Martelli, N Bolli, R Bonasso, E Ghia, MT Pallotta, D Diverio, ... Blood 108 (6), 1999-2005, 2006 | 220 | 2006 |
The p66Shc longevity gene is silenced through epigenetic modifications of an alternative promoter A Ventura, L Luzi, S Pacini, CT Baldari, PG Pelicci Journal of Biological Chemistry 277 (25), 22370-22376, 2002 | 218 | 2002 |
Genome-wide mapping of human DNA-replication origins: levels of transcription at ORC1 sites regulate origin selection and replication timing GI Dellino, D Cittaro, R Piccioni, L Luzi, S Banfi, S Segalla, M Cesaroni, ... Genome research 23 (1), 1-11, 2013 | 205 | 2013 |
Delocalization and destabilization of the Arf tumor suppressor by the leukemia-associated NPM mutant E Colombo, P Martinelli, R Zamponi, DC Shing, P Bonetti, L Luzi, ... Cancer research 66 (6), 3044-3050, 2006 | 203 | 2006 |
Oxidative stress activates a specific p53 transcriptional response that regulates cellular senescence and aging V Gambino, G De Michele, O Venezia, P Migliaccio, V Dall'Olio, L Bernard, ... Aging cell 12 (3), 435-445, 2013 | 155 | 2013 |
Transcription factor binding sites are genetic determinants of retroviral integration in the human genome B Felice, C Cattoglio, D Cittaro, A Testa, A Miccio, G Ferrari, L Luzi, ... PloS one 4 (2), e4571, 2009 | 130 | 2009 |
Cytoplasmic localization of NPM in myeloid leukemias is dictated by gain-of-function mutations that create a functional nuclear export signal AR Mariano, E Colombo, L Luzi, P Martinelli, S Volorio, L Bernard, ... Oncogene 25 (31), 4376-4380, 2006 | 106 | 2006 |
Release of paused RNA polymerase II at specific loci favors DNA double-strand-break formation and promotes cancer translocations GI Dellino, F Palluzzi, AM Chiariello, R Piccioni, S Bianco, L Furia, ... Nature genetics 51 (6), 1011-1023, 2019 | 93 | 2019 |
RaLP, a new member of the Src homology and collagen family, regulates cell migration and tumor growth of metastatic melanomas E Fagiani, G Giardina, L Luzi, M Cesaroni, M Quarto, M Capra, ... Cancer research 67 (7), 3064-3073, 2007 | 87 | 2007 |
AML1/ETO oncoprotein is directed to AML1 binding regions and co-localizes with AML1 and HEB on its targets A Gardini, M Cesaroni, L Luzi, AJ Okumura, JR Biggs, SP Minardi, ... PLoS genetics 4 (11), e1000275, 2008 | 84 | 2008 |
p53 loss in breast cancer leads to Myc activation, increased cell plasticity, and expression of a mitotic signature with prognostic value A Santoro, T Vlachou, L Luzi, G Melloni, L Mazzarella, E D’Elia, X Aobuli, ... Cell reports 26 (3), 624-638. e8, 2019 | 69 | 2019 |
In Vivo Genetic Screens of Patient-Derived Tumors Revealed Unexpected Frailty of the Transformed Phenotype D Bossi, A Cicalese, GI Dellino, L Luzi, L Riva, C D'Alesio, GR Diaferia, ... Cancer discovery 6 (6), 650-663, 2016 | 69 | 2016 |
Cerebro: interactive visualization of scRNA-seq data R Hillje, PG Pelicci, L Luzi Bioinformatics 36 (7), 2311-2313, 2020 | 65 | 2020 |