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Codruta Ignea
Codruta Ignea
Assistant Professor of Bioengineering, McGill University
在 mcgill.ca 的电子邮件经过验证 - 首页
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Engineering monoterpene production in yeast using a synthetic dominant negative geranyl diphosphate synthase
C Ignea, M Pontini, ME Maffei, AM Makris, SC Kampranis
ACS synthetic biology 3 (5), 298-306, 2014
2172014
Transforming yeast peroxisomes into microfactories for the efficient production of high-value isoprenoids
S Dusséaux, WT Wajn, Y Liu, C Ignea, SC Kampranis
Proceedings of the National Academy of Sciences 117 (50), 31789-31799, 2020
1442020
Improving yeast strains using recyclable integration cassettes, for the production of plant terpenoids
C Ignea, I Cvetkovic, S Loupassaki, P Kefalas, CB Johnson, ...
Microbial Cell Factories 10, 1-18, 2011
1322011
Efficient diterpene production in yeast by engineering Erg20p into a geranylgeranyl diphosphate synthase
C Ignea, FA Trikka, AK Nikolaidis, P Georgantea, E Ioannou, ...
Metabolic engineering 27, 65-75, 2015
1262015
Carnosic acid biosynthesis elucidated by a synthetic biology platform
C Ignea, A Athanasakoglou, E Ioannou, P Georgantea, FA Trikka, ...
Proceedings of the National Academy of Sciences 113 (13), 3681-3686, 2016
1072016
Synthesis of 11-carbon terpenoids in yeast using protein and metabolic engineering
C Ignea, M Pontini, MS Motawia, ME Maffei, AM Makris, SC Kampranis
Nature Chemical Biology 14 (12), 1090-1098, 2018
922018
Orthogonal monoterpenoid biosynthesis in yeast constructed on an isomeric substrate
C Ignea, MH Raadam, MS Motawia, AM Makris, CE Vickers, ...
Nature communications 10 (1), 3799, 2019
912019
Reconstructing the chemical diversity of labdane-type diterpene biosynthesis in yeast
C Ignea, E Ioannou, P Georgantea, S Loupassaki, FA Trikka, AK Kanellis, ...
Metabolic engineering 28, 91-103, 2015
762015
Iterative carotenogenic screens identify combinations of yeast gene deletions that enhance sclareol production
FA Trikka, A Nikolaidis, A Athanasakoglou, A Andreadelli, C Ignea, ...
Microbial Cell Factories 14, 1-19, 2015
622015
Positive genetic interactors of HMG2 identify a new set of genetic perturbations for improving sesquiterpene production in Saccharomyces cerevisiae
C Ignea, FA Trikka, I Kourtzelis, A Argiriou, AK Kanellis, SC Kampranis, ...
Microbial cell factories 11, 1-16, 2012
522012
Combined metabolome and transcriptome profiling provides new insights into diterpene biosynthesis in S. pomifera glandular trichomes
FA Trikka, A Nikolaidis, C Ignea, A Tsaballa, LA Tziveleka, E Ioannou, ...
BMC genomics 16, 1-19, 2015
492015
Modulation of the antioxidant/pro-oxidant balance, cytotoxicity and antiviral actions of grape seed extracts
C Ignea, CM Dorobanţu, CP Mintoff, N Branza-Nichita, MR Ladomery, ...
Food Chemistry 141 (4), 3967-3976, 2013
392013
Integrating pathway elucidation with yeast engineering to produce polpunonic acid the precursor of the anti-obesity agent celastrol
NL Hansen, K Miettinen, Y Zhao, C Ignea, A Andreadelli, MH Raadam, ...
Microbial Cell Factories 19, 1-17, 2020
362020
Use of the de novo transcriptome analysis of silver-leaf nightshade (Solanum elaeagnifolium) to identify gene expression changes associated with wounding and …
A Tsaballa, A Nikolaidis, F Trikka, C Ignea, SC Kampranis, AM Makris, ...
BMC genomics 16, 1-15, 2015
342015
Expanding the terpene biosynthetic code with non-canonical 16 carbon atom building blocks
C Ignea, MH Raadam, A Koutsaviti, Y Zhao, YT Duan, M Harizani, ...
Nature Communications 13 (1), 5188, 2022
302022
The downregulation of GFI1 by the EZH2-NDY1/KDM2B-JARID2 axis and by human cytomegalovirus (HCMV) associated factors allows the activation of the HCMV major IE promoter and the …
G Sourvinos, A Morou, I Sanidas, I Codruta, SA Ezell, C Doxaki, ...
PLoS pathogens 10 (5), e1004136, 2014
222014
Production of the forskolin precursor 11β-hydroxy-manoyl oxide in yeast using surrogate enzymatic activities
C Ignea, E Ioannou, P Georgantea, FA Trikka, A Athanasakoglou, ...
Microbial cell factories 15, 1-11, 2016
202016
Isoprenoid biosynthesis in the diatom Haslea ostrearia
A Athanasakoglou, E Grypioti, S Michailidou, C Ignea, AM Makris, ...
New Phytologist 222 (1), 230-243, 2019
192019
Overcoming the plasticity of plant specialized metabolism for selective diterpene production in yeast
C Ignea, A Athanasakoglou, A Andreadelli, M Apostolaki, M Iakovides, ...
Scientific Reports 7 (1), 8855, 2017
182017
Widespread biosynthesis of 16-carbon terpenoids in bacteria
YT Duan, A Koutsaviti, M Harizani, C Ignea, V Roussis, Y Zhao, E Ioannou, ...
Nature Chemical Biology 19 (12), 1532-1539, 2023
152023
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