Engineering monoterpene production in yeast using a synthetic dominant negative geranyl diphosphate synthase C Ignea, M Pontini, ME Maffei, AM Makris, SC Kampranis ACS synthetic biology 3 (5), 298-306, 2014 | 217 | 2014 |
Transforming yeast peroxisomes into microfactories for the efficient production of high-value isoprenoids S Dusséaux, WT Wajn, Y Liu, C Ignea, SC Kampranis Proceedings of the National Academy of Sciences 117 (50), 31789-31799, 2020 | 144 | 2020 |
Improving yeast strains using recyclable integration cassettes, for the production of plant terpenoids C Ignea, I Cvetkovic, S Loupassaki, P Kefalas, CB Johnson, ... Microbial Cell Factories 10, 1-18, 2011 | 132 | 2011 |
Efficient diterpene production in yeast by engineering Erg20p into a geranylgeranyl diphosphate synthase C Ignea, FA Trikka, AK Nikolaidis, P Georgantea, E Ioannou, ... Metabolic engineering 27, 65-75, 2015 | 126 | 2015 |
Carnosic acid biosynthesis elucidated by a synthetic biology platform C Ignea, A Athanasakoglou, E Ioannou, P Georgantea, FA Trikka, ... Proceedings of the National Academy of Sciences 113 (13), 3681-3686, 2016 | 107 | 2016 |
Synthesis of 11-carbon terpenoids in yeast using protein and metabolic engineering C Ignea, M Pontini, MS Motawia, ME Maffei, AM Makris, SC Kampranis Nature Chemical Biology 14 (12), 1090-1098, 2018 | 92 | 2018 |
Orthogonal monoterpenoid biosynthesis in yeast constructed on an isomeric substrate C Ignea, MH Raadam, MS Motawia, AM Makris, CE Vickers, ... Nature communications 10 (1), 3799, 2019 | 91 | 2019 |
Reconstructing the chemical diversity of labdane-type diterpene biosynthesis in yeast C Ignea, E Ioannou, P Georgantea, S Loupassaki, FA Trikka, AK Kanellis, ... Metabolic engineering 28, 91-103, 2015 | 76 | 2015 |
Iterative carotenogenic screens identify combinations of yeast gene deletions that enhance sclareol production FA Trikka, A Nikolaidis, A Athanasakoglou, A Andreadelli, C Ignea, ... Microbial Cell Factories 14, 1-19, 2015 | 62 | 2015 |
Positive genetic interactors of HMG2 identify a new set of genetic perturbations for improving sesquiterpene production in Saccharomyces cerevisiae C Ignea, FA Trikka, I Kourtzelis, A Argiriou, AK Kanellis, SC Kampranis, ... Microbial cell factories 11, 1-16, 2012 | 52 | 2012 |
Combined metabolome and transcriptome profiling provides new insights into diterpene biosynthesis in S. pomifera glandular trichomes FA Trikka, A Nikolaidis, C Ignea, A Tsaballa, LA Tziveleka, E Ioannou, ... BMC genomics 16, 1-19, 2015 | 49 | 2015 |
Modulation of the antioxidant/pro-oxidant balance, cytotoxicity and antiviral actions of grape seed extracts C Ignea, CM Dorobanţu, CP Mintoff, N Branza-Nichita, MR Ladomery, ... Food Chemistry 141 (4), 3967-3976, 2013 | 39 | 2013 |
Integrating pathway elucidation with yeast engineering to produce polpunonic acid the precursor of the anti-obesity agent celastrol NL Hansen, K Miettinen, Y Zhao, C Ignea, A Andreadelli, MH Raadam, ... Microbial Cell Factories 19, 1-17, 2020 | 36 | 2020 |
Use of the de novo transcriptome analysis of silver-leaf nightshade (Solanum elaeagnifolium) to identify gene expression changes associated with wounding and … A Tsaballa, A Nikolaidis, F Trikka, C Ignea, SC Kampranis, AM Makris, ... BMC genomics 16, 1-15, 2015 | 34 | 2015 |
Expanding the terpene biosynthetic code with non-canonical 16 carbon atom building blocks C Ignea, MH Raadam, A Koutsaviti, Y Zhao, YT Duan, M Harizani, ... Nature Communications 13 (1), 5188, 2022 | 30 | 2022 |
The downregulation of GFI1 by the EZH2-NDY1/KDM2B-JARID2 axis and by human cytomegalovirus (HCMV) associated factors allows the activation of the HCMV major IE promoter and the … G Sourvinos, A Morou, I Sanidas, I Codruta, SA Ezell, C Doxaki, ... PLoS pathogens 10 (5), e1004136, 2014 | 22 | 2014 |
Production of the forskolin precursor 11β-hydroxy-manoyl oxide in yeast using surrogate enzymatic activities C Ignea, E Ioannou, P Georgantea, FA Trikka, A Athanasakoglou, ... Microbial cell factories 15, 1-11, 2016 | 20 | 2016 |
Isoprenoid biosynthesis in the diatom Haslea ostrearia A Athanasakoglou, E Grypioti, S Michailidou, C Ignea, AM Makris, ... New Phytologist 222 (1), 230-243, 2019 | 19 | 2019 |
Overcoming the plasticity of plant specialized metabolism for selective diterpene production in yeast C Ignea, A Athanasakoglou, A Andreadelli, M Apostolaki, M Iakovides, ... Scientific Reports 7 (1), 8855, 2017 | 18 | 2017 |
Widespread biosynthesis of 16-carbon terpenoids in bacteria YT Duan, A Koutsaviti, M Harizani, C Ignea, V Roussis, Y Zhao, E Ioannou, ... Nature Chemical Biology 19 (12), 1532-1539, 2023 | 15 | 2023 |