Human lung cancer harbors spatially organized stem-immunity hubs associated with response to immunotherapy JH Chen, LT Nieman, M Spurrell, V Jorgji, L Elmelech, P Richieri, KH Xu, ... Nature Immunology 25 (4), 644-658, 2024 | 40 | 2024 |
Spatial analysis of human lung cancer reveals organized immune hubs enriched for stem-like CD8 T cells and associated with immunotherapy response JH Chen, LT Nieman, M Spurrell, V Jorgji, P Richieri, KH Xu, R Madhu, ... BioRxiv, 2023.04. 04.535379, 2023 | 17 | 2023 |
Early Immune Remodeling Steers Clinical Response to First-Line Chemoimmunotherapy in Advanced Gastric Cancer M An, A Mehta, BH Min, YJ Heo, SJ Wright, M Parikh, L Bi, H Lee, TJ Kim, ... Cancer Discovery 14 (5), 766-785, 2024 | 14 | 2024 |
Plasma proteomic biomarkers identify non-responders and reveal biological insights about the tumor microenvironment in melanoma patients after PD1 blockade A Mehta, M Rucevic, E Sprecher, M Parikh, J Chen, DT Frederick, ... bioRxiv, 2022.02. 02.478819, 2022 | 5 | 2022 |
Sequential pembrolizumab cooperates with platinum/5FU to remodel the tumor microenvironment in advanced gastric cancer: a phase II chemoimmunotherapy trial M An, A Mehta, BH Min, YJ Heo, M Parikh, L Bi, R Cristescu, H Lee, T Kim, ... medRxiv, 2023.04. 03.23288062, 2023 | 2 | 2023 |
Sequential pembrolizumab cooperates with platinum/5FU to remodel the tumor immune microenvironment in advanced gastric cancer: a phase II chemoimmunotherapy trial S Klempner, J Lee, A Mehta, M An, BH Min, YJ Heo, M Parikh, L Bi, ... | 1 | 2023 |
150 Circulatory plasma proteomic biomarkers predict response to immunotherapy in melanoma patients and reveal biological insights into the tumor microenvironment A Mehta, M Rucevic, E Sprecher, N Hacohen, G Boland, M Parikh, J Chen, ... Journal for ImmunoTherapy of Cancer 10 (Suppl 2), 2022 | 1 | 2022 |
Abstract B052: Plasma proteomic biomarkers reveal biological insights about the tumor microenvironment in melanoma patients after PD1 blockade SJ Wright, I Zamora, M Parikh, D Yeramosu, L Bi, S Kang, M Rucevic, ... Clinical Cancer Research 30 (21_Supplement), B052-B052, 2024 | | 2024 |
Abstract PR018: Plasma proteomic biomarkers reveal biological insights about the tumor microenvironment in melanoma patients after PD1 blockade SJ Wright, I Zamora, M Parikh, D Yeramosu, L Bi, S Kang, M Rucevic, ... Clinical Cancer Research 30 (21_Supplement), PR018-PR018, 2024 | | 2024 |
Abstract A010: Tumor-reactive T cell clonal dynamics across treatment time points drive resistance and progression to frontline chemoimmunotherapy in advanced gastric cancer SJ Wright, M An, BH Min, YJ Heo, M Parikh, L Bi, H Lee, T Kim, SY Lee, ... Cancer Immunology Research 12 (10_Supplement), A010-A010, 2024 | | 2024 |
Characterization of cell states in biliary tract cancers identifies mechanisms of therapeutic resistance in a phase II trial of DKN-01/nivolumab RJ Park, M Parikh, L Pappas, M Sade-Feldman, AS Kulkarni, L Bi, ... medRxiv, 2024 | | 2024 |
Abstract C065: PlastiNet: Understanding the Epithelial-Mesenchymal Transition Through Graphical Attention in Spatial Transcriptomics IL Zamora, M Parikh, S Wright, L Bi, B Patel, D Pe’er, D Ting, N Hacohen, ... Cancer Research 84 (17_Supplement_2), C065-C065, 2024 | | 2024 |
Abstract NG08: Dissecting and quantifying pancreatic cancer plasticity using single-cell multiomics, lineage tracing and functional genomics reveals novel mediators of therapy … A Mehta, L Bi, D Yeramosu, M Bogaev, M Jankowiak, A Collins, ... Cancer Research 84 (7_Supplement), NG08-NG08, 2024 | | 2024 |
Understanding spatial organization of cellular plasticity in pancreatic ductal adenocarcinoma I Zamora, M Parikh, BK Patel, L Bi, D Haviv, J Cao, C Shiau, M Hemberg, ... Cancer Research 84 (6_Supplement), 3873-3873, 2024 | | 2024 |
Understanding radiation and immunotherapy induced cell state shifts in the pancreatic tumor microenvironment M Parikh, R Park, AR Parikh, JL Koenig, L Pappas, M Sade-Feldman, L Bi, ... Cancer Research 84 (6_Supplement), 1194-1194, 2024 | | 2024 |
Spatial organization and cellular composition of immunity hubs in human colorectal cancer MG Palshikar, M Spurrell, J Demaray, H Chen, S Engels, R Madhu, ... Cancer Research 84 (6_Supplement), 5492-5492, 2024 | | 2024 |
The transcriptional and epigenetic regulation of epithelial-mesenchymal plasticity in patient-derived pancreatic cancer cell lines D Yeramosu, L Bi, A Collins, M Bogaev, M Jankowiak, A Al’Khafaji, ... Cancer Research 84 (6_Supplement), 6940-6940, 2024 | | 2024 |
Tumor cell metaplastic programs and failure of T cell remodeling drive resistance and progression to frontline chemoimmunotherapy in advanced gastric cancer SJ Wright, M An, BH Min, YJ Heo, M Parikh, L Bi, H Lee, T Kim, SY Lee, ... Cancer Research 84 (6_Supplement), 6846-6846, 2024 | | 2024 |
Plasma proteomic biomarkers identify non-responders and reveal biological insights about the tumor microenvironment in melanoma patients after PD1 blockade SJ Wright, D Yeramosu, M Parikh, M Rucevic, N Nguyen, RW Jenkins, ... Cancer Research 84 (6_Supplement), 1854-1854, 2024 | | 2024 |
Quantifying and dissecting pancreatic cancer cell phenotypic plasticity using lineage tracing, single-cell multiomics and CRISPR perturbations reveals novel regulators of … A Mehta, L Bi, A Al'Khafaji, M Jankowiak, M Parikh, M Babadi, ... CANCER RESEARCH 82 (22), 67-67, 2022 | | 2022 |