Robust prediction of response to immune checkpoint blockade therapy in metastatic melanoma N Auslander, G Zhang, JS Lee, DT Frederick, B Miao, T Moll, T Tian, ... Nature medicine 24 (10), 1545-1549, 2018 | 591 | 2018 |
Genomic determinants of pathogenicity in SARS-CoV-2 and other human coronaviruses AB Gussow*, N Auslander*, G Faure, YI Wolf, F Zhang, EV Koonin Proceedings of the National Academy of Sciences, 2020 | 253 | 2020 |
Urea cycle dysregulation generates clinically relevant genomic and biochemical signatures JS Lee, L Adler, H Karathia, N Carmel, S Rabinovich, N Auslander, ... Cell 174 (6), 1559-1570. e22, 2018 | 223 | 2018 |
Chemoradiotherapy resistance in colorectal cancer cells is mediated by Wnt/β-catenin signaling G Emons, M Spitzner, S Reineke, J Möller, N Auslander, F Kramer, Y Hu, ... Molecular Cancer Research 15 (11), 1481-1490, 2017 | 132 | 2017 |
Harnessing synthetic lethality to predict the response to cancer treatment JS Lee, A Das, L Jerby-Arnon, R Arafeh, N Auslander, M Davidson, ... Nature communications 9 (1), 2546, 2018 | 119 | 2018 |
The microbiome-derived metabolite TMAO drives immune activation and boosts responses to immune checkpoint blockade in pancreatic cancer G Mirji, A Worth, SA Bhat, M El Sayed, T Kannan, AR Goldman, HY Tang, ... Science immunology 7 (75), eabn0704, 2022 | 102 | 2022 |
Seeker: alignment-free identification of bacteriophage genomes by deep learning N Auslander, AB Gussow, S Benler, YI Wolf, EV Koonin Nucleic acids research 48 (21), e121-e121, 2020 | 97 | 2020 |
Incorporating machine learning into established bioinformatics frameworks N Auslander, AB Gussow, EV Koonin International journal of molecular sciences 22 (6), 2903, 2021 | 76 | 2021 |
Co-targeting the tumor endothelium and P-selectin-expressing glioblastoma cells leads to a remarkable therapeutic outcome S Ferber, G Tiram, A Sousa-Herves, A Eldar-Boock, A Krivitsky, ... Elife 6, e25281, 2017 | 73 | 2017 |
A joint analysis of transcriptomic and metabolomic data uncovers enhanced enzyme-metabolite coupling in breast cancer N Auslander, K Yizhak, A Weinstock, A Budhu, W Tang, XW Wang, ... Scientific reports 6 (1), 29662, 2016 | 55 | 2016 |
An integrated computational and experimental study uncovers FUT 9 as a metabolic driver of colorectal cancer N Auslander, CE Cunningham, BM Toosi, EJ McEwen, K Yizhak, ... Molecular Systems Biology 13 (12), 956, 2017 | 44 | 2017 |
Predicting complete remission of acute myeloid leukemia: machine learning applied to gene expression O Gal, N Auslander, Y Fan, D Meerzaman Cancer informatics 18, 1176935119835544, 2019 | 42 | 2019 |
Pyrvinium pamoate induces death of triple-negative breast cancer stem–like cells and reduces metastases through effects on lipid anabolism R Dattilo, C Mottini, E Camera, A Lamolinara, N Auslander, G Doglioni, ... Cancer research 80 (19), 4087-4102, 2020 | 40 | 2020 |
Interplay between DNA damage repair and apoptosis shapes cancer evolution through aneuploidy and microsatellite instability N Auslander, YI Wolf, EV Koonin Nature communications 11 (1), 1234, 2020 | 28 | 2020 |
Prediction of the incubation period for COVID-19 and future virus disease outbreaks AB Gussow*, N Auslander*, YI Wolf, EV Koonin BMC biology 18 (1), 1-12, 2020 | 26* | 2020 |
In silico learning of tumor evolution through mutational time series N Auslander, YI Wolf, EV Koonin Proceedings of the National Academy of Sciences 116 (19), 9501-9510, 2019 | 26 | 2019 |
Mutated processes predict immune checkpoint inhibitor therapy benefit in metastatic melanoma A Patterson, N Auslander Nature Communications 13 (1), 5151, 2022 | 19 | 2022 |
Hard wiring of normal tissue-specific chromosome-wide gene expression levels is an additional factor driving cancer type-specific aneuploidies S Patkar, K Heselmeyer-Haddad*, N Auslander*, D Hirsch, J Camps, ... Genome medicine 13 (1), 1-16, 2021 | 19* | 2021 |
Functional genomic complexity defines intratumor heterogeneity and tumor aggressiveness in liver cancer SM Kwon, A Budhu, HG Woo, J Chaisaingmongkol, H Dang, M Forgues, ... Scientific Reports 9 (1), 16930, 2019 | 19 | 2019 |
Single-Cell–Derived Primary Rectal Carcinoma Cell Lines Reflect Intratumor Heterogeneity Associated with Treatment Response R Braun, L Anthuber, D Hirsch, D Wangsa, J Lack, NE McNeil, ... Clinical Cancer Research 26 (13), 3468-3480, 2020 | 17 | 2020 |