Phosphodiesterase type 5 is highly expressed in the hypertrophied human right ventricle, and acute inhibition of phosphodiesterase type 5 improves contractility J Nagendran, SL Archer, D Soliman, V Gurtu, R Moudgil, A Haromy, ... Circulation 116 (3), 238-248, 2007 | 621 | 2007 |
Genome‐wide hypermutation in a subpopulation of stationary‐phase cells underlies recombination‐dependent adaptive mutation J Torkelson, RS Harris, MJ Lombardo, J Nagendran, C Thulin, ... The EMBO journal, 1997 | 301 | 1997 |
Inhibition of pyruvate dehydrogenase kinase improves pulmonary arterial hypertension in genetically susceptible patients ED Michelakis, V Gurtu, L Webster, G Barnes, G Watson, L Howard, ... Science translational medicine 9 (413), eaao4583, 2017 | 265 | 2017 |
A metabolic remodeling in right ventricular hypertrophy is associated with decreased angiogenesis and a transition from a compensated to a decompensated state in pulmonary … G Sutendra, P Dromparis, R Paulin, S Zervopoulos, A Haromy, ... Journal of molecular medicine 91, 1315-1327, 2013 | 234 | 2013 |
Normothermic ex-vivo preservation with the portable Organ Care System Lung device for bilateral lung transplantation (INSPIRE): a randomised, open-label, non-inferiority, phase … G Warnecke, D Van Raemdonck, MA Smith, G Massard, J Kukreja, F Rea, ... The Lancet Respiratory Medicine 6 (5), 357-367, 2018 | 186 | 2018 |
Dehydroepiandrosterone reverses systemic vascular remodeling through the inhibition of the Akt/GSK3-β/NFAT axis S Bonnet, R Paulin, G Sutendra, P Dromparis, M Roy, KO Watson, ... Circulation 120 (13), 1231-1240, 2009 | 153 | 2009 |
CD36 expression contributes to age-induced cardiomyopathy in mice DPY Koonen, M Febbraio, S Bonnet, J Nagendran, ME Young, ... Circulation 116 (19), 2139-2147, 2007 | 147 | 2007 |
A dynamic and chamber-specific mitochondrial remodeling in right ventricular hypertrophy can be therapeutically targeted J Nagendran, V Gurtu, DZ Fu, JRB Dyck, A Haromy, DB Ross, ... the Journal of thoracic and cardiovascular surgery 136 (1), 168-178. e3, 2008 | 121 | 2008 |
Pretreatment with angiotensin-converting enzyme inhibitor improves doxorubicin-induced cardiomyopathy via preservation of mitochondrial function A Hiona, AS Lee, J Nagendran, X Xie, AJ Connolly, RC Robbins, JC Wu The Journal of thoracic and cardiovascular surgery 142 (2), 396-403. e3, 2011 | 102 | 2011 |
Transplantation of hearts donated after circulatory death CW White, SJ Messer, SR Large, J Conway, DH Kim, DJ Kutsogiannis, ... Frontiers in cardiovascular medicine 5, 8, 2018 | 101 | 2018 |
Coronary artery bypass surgery improves outcomes in patients with diabetes and left ventricular dysfunction J Nagendran, SJ Bozso, CM Norris, FA McAlister, JJ Appoo, MC Moon, ... Journal of the American College of Cardiology 71 (8), 819-827, 2018 | 96 | 2018 |
An anesthesiologist's guide to hypoxic pulmonary vasoconstriction: implications for managing single-lung anesthesia and atelectasis J Nagendran, K Stewart, M Hoskinson, SL Archer Current Opinion in Anesthesiology 19 (1), 34-43, 2006 | 86 | 2006 |
Assessment of donor heart viability during ex vivo heart perfusion CW White, E Ambrose, A Müller, Y Li, H Le, B Hiebert, R Arora, TW Lee, ... Canadian journal of physiology and pharmacology 93 (10), 893-901, 2015 | 85 | 2015 |
Endothelin axis is upregulated in human and rat right ventricular hypertrophy J Nagendran, G Sutendra, I Paterson, HC Champion, L Webster, B Chiu, ... Circulation research 112 (2), 347-354, 2013 | 77 | 2013 |
Physiologic changes in the heart following cessation of mechanical ventilation in a porcine model of donation after circulatory death: implications for cardiac transplantation CW White, R Lillico, J Sandha, D Hasanally, F Wang, E Ambrose, A Müller, ... American Journal of Transplantation 16 (3), 783-793, 2016 | 72 | 2016 |
Is mitral valve surgery safe in octogenarians? J Nagendran, C Norris, A Maitland, A Koshal, DB Ross European journal of cardio-thoracic surgery 28 (1), 83-87, 2005 | 69 | 2005 |
Negative pressure ventilation decreases inflammation and lung edema during normothermic ex-vivo lung perfusion NS Aboelnazar, S Himmat, S Hatami, CW White, MS Burhani, ... The Journal of Heart and Lung Transplantation 37 (4), 520-530, 2018 | 58 | 2018 |
Predicting cardiovascular intensive care unit readmission after cardiac surgery: derivation and validation of the Alberta Provincial Project for Outcomes Assessment in Coronary … S van Diepen, MM Graham, J Nagendran, CM Norris Critical Care 18, 1-9, 2014 | 58 | 2014 |
Elevation of plasma homocysteine levels associated with acute myocardial infarction MPJ Senaratne, J Griffiths, J Nagendran Clinical and investigative medicine 23 (4), 220-226, 2000 | 54 | 2000 |
Feasibility of direct discharge from the coronary/intermediate care unit after acute myocardial infarction MPJ Senaratne, ME Irwin, S Shaben, J Griffiths, J Nagendran, L Kasza, ... Journal of the American college of Cardiology 33 (4), 1040-1046, 1999 | 48 | 1999 |