Resetting the epigenetic balance of Polycomb and COMPASS function at enhancers for cancer therapy L Wang, Z Zhao, PA Ozark, D Fantini, SA Marshall, EJ Rendleman, ... Nature medicine 24 (6), 758-769, 2018 | 159 | 2018 |
PAF1 regulation of promoter-proximal pause release via enhancer activation FX Chen, P Xie, CK Collings, K Cao, Y Aoi, SA Marshall, EJ Rendleman, ... Science 357 (6357), 1294-1298, 2017 | 139 | 2017 |
TET2 coactivates gene expression through demethylation of enhancers L Wang, PA Ozark, ER Smith, Z Zhao, SA Marshall, EJ Rendleman, ... Science advances 4 (11), eaau6986, 2018 | 117 | 2018 |
Targeting processive transcription elongation via SEC disruption for MYC-induced cancer therapy K Liang, ER Smith, Y Aoi, KL Stoltz, H Katagi, AR Woodfin, EJ Rendleman, ... Cell 175 (3), 766-779. e17, 2018 | 109 | 2018 |
Histone H3K4 methylation-dependent and-independent functions of Set1A/COMPASS in embryonic stem cell self-renewal and differentiation CC Sze, K Cao, CK Collings, SA Marshall, EJ Rendleman, PA Ozark, ... Genes & development 31 (17), 1732-1737, 2017 | 95 | 2017 |
An Mll4/COMPASS-Lsd1 epigenetic axis governs enhancer function and pluripotency transition in embryonic stem cells K Cao, CK Collings, MA Morgan, SA Marshall, EJ Rendleman, PA Ozark, ... Science advances 4 (1), eaap8747, 2018 | 75 | 2018 |
High-fat high-sugar diet induces polycystic ovary syndrome in a rodent model JS Roberts, RA Perets, KS Sarfert, JJ Bowman, PA Ozark, GB Whitworth, ... Biology of reproduction 96 (3), 551-562, 2017 | 60 | 2017 |
Epigenetic targeted therapy of stabilized BAP1 in ASXL1 gain-of-function mutated leukemia L Wang, NW Birch, Z Zhao, CM Nestler, A Kazmer, A Shilati, A Blake, ... Nature Cancer 2 (5), 515-526, 2021 | 54 | 2021 |
DOT1L-controlled cell-fate determination and transcription elongation are independent of H3K79 methylation K Cao, M Ugarenko, PA Ozark, J Wang, SA Marshall, EJ Rendleman, ... Proceedings of the National Academy of Sciences 117 (44), 27365-27373, 2020 | 52 | 2020 |
Coordinated regulation of cellular identity–associated H3K4me3 breadth by the COMPASS family CC Sze, PA Ozark, K Cao, M Ugarenko, S Das, LU Wang, SA Marshall, ... Science advances 6 (26), eaaz4764, 2020 | 47 | 2020 |
Tenascin-C expression contributes to pediatric brainstem glioma tumor phenotype and represents a novel biomarker of disease J Qi, DR Esfahani, T Huang, P Ozark, E Bartom, R Hashizume, ER Bonner, ... Acta neuropathologica communications 7, 1-19, 2019 | 33 | 2019 |
IFN-γ–inducible antiviral responses require ULK1-mediated activation of MLK3 and ERK5 D Saleiro, GT Blyth, EM Kosciuczuk, PA Ozark, B Majchrzak-Kita, ... Science signaling 11 (557), eaap9921, 2018 | 29 | 2018 |
A small UTX stabilization domain of Trr is conserved within mammalian MLL3-4/COMPASS and is sufficient to rescue loss of viability in null animals R Rickels, L Wang, M Iwanaszko, PA Ozark, MA Morgan, A Piunti, ... Genes & Development 34 (21-22), 1493-1502, 2020 | 19 | 2020 |
ETV6 represses inflammatory response genes and regulates HSPC function during stress hematopoiesis in mice M Bloom, N Oak, R Baskin-Doerfler, R Feng, I Iacobucci, P Baviskar, ... Blood Advances 7 (18), 5608-5623, 2023 | 7 | 2023 |
ATRT-02. THERAPEUTIC TARGETING OF EZH2 AND BET BRD4 IN AT/RT A Zhang, A Piunti, P Ozark, X He, H Katagi, T Sasaki, K Laurie, ... Neuro-Oncology 21 (Suppl 2), ii63, 2019 | 2 | 2019 |
ETV6 Represses TNF during Stress Hematopoiesis and Regulates HSC Self Renewal M Bloom, R Baskin-Doerfler, N Oak, R Feng, X Zhao, C Li, P Ozark, ... Blood 140 (Supplement 1), 2849-2850, 2022 | 1 | 2022 |
Effects of Diet‐induced Obesity and Estrogen on the Female Rat Fecal Microbiome PA Ozark, SN Blythe, N Toporikova, GB Whitworth The FASEB Journal 31, 138.2-138.2, 2017 | 1 | 2017 |
3036–ETV6 REPRESSES TNF EXPRESSION IN HSCS DURING STRESS HEMATOPOIESIS AND REGULATES HSC SELF-RENEWAL M Bloom, R Baskin-Doerfler, N Oak, R Feng, X Zhao, P Ozark, A Stroh, ... Experimental Hematology 111, S62-S63, 2022 | | 2022 |
3049–THROMBOCYTOPENIA 5-ASSOCIATED GERMLINE ETV6 VARIANT IMPAIRS THE HEMATOPOIETIC STEM AND PROGENITOR CELL STRESS RESPONSE AND INDUCES AN INFLAMMATORY GENE SIGNATURE M Bloom, R Baskin-Doerfler, N Oak, P Ozark, K Verbist, A Stroh, C Li, ... Experimental Hematology 100, S66, 2021 | | 2021 |
PDTM-31. INVESTIGATING THE EFFECT OF H3G34V MUTATION ON DISTINCT GENOMIC H3K36 METHYLATION PATTERNS IN PEDIATRIC GLIOMA T Huang, A Piunti, P Ozark, E Barton, J Qi, R Hashizume, A Shilatifard, ... Neuro-Oncology 21 (Suppl 6), vi194, 2019 | | 2019 |