| Mechanism and inhibition of the papain‐like protease, PLpro, of SARS‐CoV‐2 T Klemm, G Ebert, DJ Calleja, CC Allison, LW Richardson, JP Bernardini, ... The EMBO journal 39 (18), e106275, 2020 | 409 | 2020 |
| Eliminating hepatitis B by antagonizing cellular inhibitors of apoptosis G Ebert, C Allison, S Preston, J Cooney, JG Toe, MD Stutz, S Ojaimi, ... Proceedings of the National Academy of Sciences 112 (18), 5803-5808, 2015 | 141 | 2015 |
| Nanobody cocktails potently neutralize SARS-CoV-2 D614G N501Y variant and protect mice P Pymm, A Adair, LJ Chan, JP Cooney, FL Mordant, CC Allison, E Lopez, ... Proceedings of the National Academy of Sciences 118 (19), e2101918118, 2021 | 121 | 2021 |
| Cellular inhibitor of apoptosis proteins prevent clearance of hepatitis B virus G Ebert, S Preston, C Allison, J Cooney, JG Toe, MD Stutz, S Ojaimi, ... Proceedings of the National Academy of Sciences 112 (18), 5797-5802, 2015 | 112 | 2015 |
| Interferon-γ primes macrophages for pathogen ligand-induced killing via a caspase-8 and mitochondrial cell death pathway DS Simpson, J Pang, A Weir, IY Kong, M Fritsch, M Rashidi, JP Cooney, ... Immunity 55 (3), 423-441. e9, 2022 | 82 | 2022 |
| ARIH2 is essential for embryogenesis, and its hematopoietic deficiency causes lethal activation of the immune system AE Lin, G Ebert, Y Ow, SP Preston, JG Toe, JP Cooney, HW Scott, ... Nature immunology 14 (1), 27-33, 2013 | 42 | 2013 |
| Epigenetic silencing of RIPK3 in hepatocytes prevents MLKL-mediated necroptosis from contributing to liver pathologies SP Preston, MD Stutz, CC Allison, U Nachbur, Q Gouil, BM Tran, ... Gastroenterology 163 (6), 1643-1657. e14, 2022 | 39 | 2022 |
| Programmed cell death: the pathways to severe COVID-19? SM Bader, JP Cooney, M Pellegrini, M Doerflinger Biochemical Journal 479 (5), 609-628, 2022 | 39 | 2022 |
| Landscape of human antibody recognition of the SARS-CoV-2 receptor binding domain AK Wheatley, P Pymm, R Esterbauer, MH Dietrich, WS Lee, D Drew, ... Cell Reports 37 (2), 2021 | 38 | 2021 |
| Insights into drug Repurposing, as well as specificity and compound properties of piperidine-based SARS-CoV-2 PLpro inhibitors DJ Calleja, N Kuchel, BGC Lu, RW Birkinshaw, T Klemm, M Doerflinger, ... Frontiers in Chemistry 10, 861209, 2022 | 19 | 2022 |
| Caspase-8 has dual roles in regulatory T cell homeostasis balancing immunity to infection and collateral inflammatory damage CE Teh, SP Preston, AK Robbins, MD Stutz, J Cooney, MP Clark, ... Science Immunology 7 (69), eabn8041, 2022 | 13 | 2022 |
| Venetoclax, alone and in combination with the BH3 mimetic S63845, depletes HIV-1 latently infected cells and delays rebound in humanized mice P Arandjelovic, Y Kim, JP Cooney, SP Preston, M Doerflinger, ... Cell Reports Medicine 4 (9), 2023 | 10 | 2023 |
| Rapid detection of monkeypox virus using a CRISPR-Cas12a mediated assay: a laboratory validation and evaluation study SJ Low, M T O'Neill, WJ Kerry, M Krysiak, G Papadakis, LW Whitehead, ... The Lancet Microbe 4 (10), e800-e810, 2023 | 8 | 2023 |
| SARS-CoV-2 mouse adaptation selects virulence mutations that cause TNF-driven age-dependent severe disease with human correlates SM Bader, JP Cooney, D Sheerin, G Taiaroa, L Harty, KC Davidson, ... Proceedings of the National Academy of Sciences 120 (32), e2301689120, 2023 | 8 | 2023 |
| Therapeutic manipulation of host cell death pathways to facilitate clearance of persistent viral infections J Cooney, C Allison, S Preston, M Pellegrini Journal of Leukocyte Biology 103 (2), 287-293, 2018 | 8 | 2018 |
| Broad immunity to SARS-CoV-2 variants of concern mediated by a SARS-CoV-2 receptor-binding domain protein vaccine G Deliyannis, NA Gherardin, CY Wong, SL Grimley, JP Cooney, ... EBioMedicine 92, 2023 | 7 | 2023 |
| The role of MKK4 in T‐cell development and immunity to viral infections SP Preston, M Doerflinger, HW Scott, CC Allison, M Horton, J Cooney, ... Immunology and cell biology 99 (4), 428-435, 2021 | 7 | 2021 |
| Fc engineered ACE2-Fc is a potent multifunctional agent targeting SARS-CoV2 BD Wines, L Kurtovic, HM Trist, S Esparon, E Lopez, K Chappin, LJ Chan, ... Frontiers in immunology 13, 889372, 2022 | 6 | 2022 |
| Necroptosis does not drive disease pathogenesis in a mouse infective model of SARS-CoV-2 in vivo S M. Bader, JP Cooney, R Bhandari, L Mackiewicz, M Dayton, D Sheerin, ... Cell Death & Disease 15 (1), 100, 2024 | 4 | 2024 |
| Biparatopic nanobodies targeting the receptor binding domain efficiently neutralize SARS-CoV-2 P Pymm, SJ Redmond, O Dolezal, F Mordant, E Lopez, JP Cooney, ... Iscience 25 (11), 2022 | 4 | 2022 |
