Mixed micelles of the antihistaminic cationic drug diphenhydramine hydrochloride with anionic and non-ionic surfactants show improved solubility, drug release and cytotoxicity … A Srivastava, H Uchiyama, Y Wada, Y Hatanaka, Y Shirakawa, K Kadota, ... Journal of Molecular liquids 277, 349-359, 2019 | 63 | 2019 |
A strategy for co-former selection to design stable co-amorphous formations based on physicochemical properties of non-steroidal inflammatory drugs H Ueda, N Muranushi, S Sakuma, Y Ida, T Endoh, K Kadota, Y Tozuka Pharmaceutical research 33, 1018-1029, 2016 | 59 | 2016 |
Development of porous particles using dextran as an excipient for enhanced deep lung delivery of rifampicin K Kadota, Y Yanagawa, T Tachikawa, Y Deki, H Uchiyama, Y Shirakawa, ... International journal of pharmaceutics 555, 280-290, 2019 | 58 | 2019 |
Co-amorphous formation induced by combination of tranilast and diphenhydramine hydrochloride H Ueda, K Kadota, M Imono, T Ito, A Kunita, Y Tozuka Journal of Pharmaceutical Sciences 106 (1), 123-128, 2017 | 55 | 2017 |
Enhanced solubility of quercetin by forming composite particles with transglycosylated materials M Fujimori, K Kadota, K Shimono, Y Shirakawa, H Sato, Y Tozuka Journal of Food Engineering 149, 248-254, 2015 | 55 | 2015 |
Evaluation of highly branched cyclic dextrin in inhalable particles of combined antibiotics for the pulmonary delivery of anti-tuberculosis drugs K Kadota, A Senda, H Tagishi, JO Ayorinde, Y Tozuka International Journal of Pharmaceutics 517 (1-2), 8-18, 2017 | 49 | 2017 |
Anti-plasticizing effect of amorphous indomethacin induced by specific intermolecular interactions with PVA copolymer H Ueda, S Aikawa, Y Kashima, J Kikuchi, Y Ida, T Tanino, K Kadota, ... Journal of pharmaceutical sciences 103 (9), 2829-2838, 2014 | 49 | 2014 |
Raman mapping for kinetic analysis of crystallization of amorphous drug based on distributional images H Ueda, Y Ida, K Kadota, Y Tozuka International journal of pharmaceutics 462 (1-2), 115-122, 2014 | 45 | 2014 |
Kinetics of co-crystal formation with caffeine and citric acid via liquid-assisted grinding analyzed using the distinct element method K Shimono, K Kadota, Y Tozuka, A Shimosaka, Y Shirakawa, J Hidaka European Journal of Pharmaceutical Sciences 76, 217-224, 2015 | 44 | 2015 |
A particle technology approach toward designing dry-powder inhaler formulations for personalized medicine in respiratory diseases K Kadota, TR Sosnowski, S Tobita, I Tachibana, JY Tse, H Uchiyama, ... Advanced Powder Technology 31 (1), 219-226, 2020 | 42 | 2020 |
Preparation of composite particles of hydrophilic or hydrophobic drugs with highly branched cyclic dextrin via spray drying for dry powder inhalers K Kadota, T Nishimura, D Hotta, Y Tozuka Powder Technology 283, 16-23, 2015 | 41 | 2015 |
Formation and morphology of asymmetric NaCl particles precipitated at the liquid-liquid interface K Kadota, Y Shirakawa, I Matsumoto, A Shimosaka, J Hidaka Advanced Powder Technology 18 (6), 775-785, 2007 | 41 | 2007 |
The elucidation of key factors for oral absorption enhancement of nanocrystal formulations: In vitro–in vivo correlation of nanocrystals M Imono, H Uchiyama, S Yoshida, S Miyazaki, N Tamura, ... European Journal of Pharmaceutics and Biopharmaceutics 146, 84-92, 2020 | 39 | 2020 |
Delivering crocetin across the blood-brain barrier by using γ-cyclodextrin to treat Alzheimer’s disease KH Wong, Y Xie, X Huang, K Kadota, XS Yao, Y Yu, X Chen, A Lu, Z Yang Scientific reports 10 (1), 3654, 2020 | 38 | 2020 |
Absorption improvement of tranilast by forming highly soluble nano-size composite structures associated with α-glucosyl rutin via spray drying H Sato, M Fujimori, H Suzuki, K Kadota, Y Shirakawa, S Onoue, Y Tozuka European Journal of Pharmaceutics and Biopharmaceutics 92, 49-55, 2015 | 36 | 2015 |
Morphology control of amino acid particles in interfacial crystallization using inkjet nozzle H Tamura, K Kadota, Y Shirakawa, Y Tozuka, A Shimosaka, J Hidaka Advanced Powder Technology 25 (3), 847-852, 2014 | 36 | 2014 |
Effects of inhalation procedure on particle behavior and deposition in the airways analyzed by numerical simulation K Kadota, A Imanaka, M Shimazaki, T Takemiya, K Kubo, H Uchiyama, ... Journal of the Taiwan Institute of Chemical Engineers 90, 44-50, 2018 | 35 | 2018 |
Evaluation of the micellization mechanism of an amphipathic graft copolymer with enhanced solubility of ipriflavone S Tanida, T Kurokawa, H Sato, K Kadota, Y Tozuka Chemical and Pharmaceutical Bulletin 64 (1), 68-72, 2016 | 35 | 2016 |
Drug solubilization mechanism of α-glucosyl stevia by NMR spectroscopy J Zhang, K Higashi, K Ueda, K Kadota, Y Tozuka, W Limwikrant, ... International Journal of Pharmaceutics 465 (1-2), 255-261, 2014 | 34 | 2014 |
Production of asymmetrical particles in a crystallization process using liquid–liquid interfaces K Kadota, S Tanida, Y Shirakawa, A Shimosaka, J Hidaka Journal of Chemical Engineering of Japan 40 (3), 217-221, 2007 | 33 | 2007 |