A CXCL1 paracrine network links cancer chemoresistance and metastasis S Acharyya, T Oskarsson, S Vanharanta, S Malladi, J Kim, PG Morris, ... Cell 150 (1), 165-178, 2012 | 1149 | 2012 |
Breast cancer cells produce tenascin C as a metastatic niche component to colonize the lungs T Oskarsson, S Acharyya, XHF Zhang, S Vanharanta, SF Tavazoie, ... Nature medicine 17 (7), 867-874, 2011 | 965 | 2011 |
Origins of metastatic traits S Vanharanta, J Massagué Cancer cell 24 (4), 410-421, 2013 | 620 | 2013 |
The common colorectal cancer predisposition SNP rs6983267 at chromosome 8q24 confers potential to enhanced Wnt signaling S Tuupanen, M Turunen, R Lehtonen, O Hallikas, S Vanharanta, T Kivioja, ... Nature genetics 41 (8), 885-890, 2009 | 598 | 2009 |
Therapy-induced tumour secretomes promote resistance and tumour progression AC Obenauf, Y Zou, AL Ji, S Vanharanta, W Shu, H Shi, X Kong, ... Nature 520 (7547), 368-372, 2015 | 489 | 2015 |
Early-onset renal cell carcinoma as a novel extraparaganglial component of SDHB-associated heritable paraganglioma S Vanharanta, M Buchta, SR McWhinney, SK Virta, M Peçzkowska, ... The American Journal of Human Genetics 74 (1), 153-159, 2004 | 473 | 2004 |
Epigenetic expansion of VHL-HIF signal output drives multiorgan metastasis in renal cancer S Vanharanta, W Shu, F Brenet, AA Hakimi, A Heguy, A Viale, VE Reuter, ... Nature medicine 19 (1), 50-56, 2013 | 228 | 2013 |
Transcription factor PROX1 induces colon cancer progression by promoting the transition from benign to highly dysplastic phenotype TV Petrova, A Nykänen, C Norrmén, KI Ivanov, LC Andersson, C Haglund, ... Cancer cell 13 (5), 407-419, 2008 | 218 | 2008 |
Biallelic inactivation of fumarate hydratase (FH) occurs in nonsyndromic uterine leiomyomas but is rare in other tumors R Lehtonen, M Kiuru, S Vanharanta, J Sjöberg, LM Aaltonen, K Aittomäki, ... The American journal of pathology 164 (1), 17-22, 2004 | 205 | 2004 |
Serrated carcinomas form a subclass of colorectal cancer with distinct molecular basis P Laiho, A Kokko, S Vanharanta, R Salovaara, H Sammalkorpi, ... Oncogene 26 (2), 312-320, 2007 | 189 | 2007 |
Loss of the multifunctional RNA-binding protein RBM47 as a source of selectable metastatic traits in breast cancer S Vanharanta, CB Marney, W Shu, M Valiente, Y Zou, A Mele, RB Darnell, ... elife 3, e02734, 2014 | 161 | 2014 |
Acquired resistance to anti-MAPK targeted therapy confers an immune-evasive tumor microenvironment and cross-resistance to immunotherapy in melanoma L Haas, A Elewaut, CL Gerard, C Umkehrer, L Leiendecker, M Pedersen, ... Nature cancer 2 (7), 693-708, 2021 | 129 | 2021 |
Allelic Imbalance at rs6983267 Suggests Selection of the Risk Allele in Somatic Colorectal Tumor Evolution S Tuupanen, I Niittymäki, K Nousiainen, S Vanharanta, JP Mecklin, ... Cancer research 68 (1), 14-17, 2008 | 86 | 2008 |
Distinct expression profile in fumarate-hydratase-deficient uterine fibroids S Vanharanta, PJ Pollard, HJ Lehtonen, P Laiho, J Sjöberg, A Leminen, ... Human molecular genetics 15 (1), 97-103, 2006 | 80 | 2006 |
Expression profiling in progressive stages of fumarate-hydratase deficiency: the contribution of metabolic changes to tumorigenesis H Ashrafian, L O'Flaherty, J Adam, V Steeples, YL Chung, P East, ... Cancer research 70 (22), 9153-9165, 2010 | 77 | 2010 |
Metabolic profiling reveals a dependency of human metastatic breast cancer on mitochondrial serine and one-carbon unit metabolism AM Li, GS Ducker, Y Li, JA Seoane, Y Xiao, S Melemenidis, Y Zhou, L Liu, ... Molecular Cancer Research 18 (4), 599-611, 2022 | 72 | 2022 |
A KLF6-driven transcriptional network links lipid homeostasis and tumour growth in renal carcinoma SE Syafruddin, P Rodrigues, E Vojtasova, SA Patel, MN Zaini, J Burge, ... Nature communications 10 (1), 1152, 2019 | 72 | 2019 |
Epigenetic determinants of metastasis SA Patel, S Vanharanta Molecular oncology 11 (1), 79-96, 2017 | 65 | 2017 |
Metastatic competence can emerge with selection of preexisting oncogenic alleles without a need of new mutations LS Jacob, S Vanharanta, AC Obenauf, M Pirun, A Viale, ND Socci, ... Cancer research 75 (18), 3713-3719, 2015 | 65 | 2015 |
Field cancerization: something new under the sun S Vanharanta, J Massagué Cell 149 (6), 1179-1181, 2012 | 50 | 2012 |