Dopamine neurons derived from human ES cells efficiently engraft in animal models of Parkinson’s disease S Kriks, JW Shim, J Piao, YM Ganat, DR Wakeman, Z Xie, L Carrillo-Reid, ... Nature 480 (7378), 547-551, 2011 | 2161 | 2011 |
Behavioral improvement in a primate Parkinson's model is associated with multiple homeostatic effects of human neural stem cells DE Redmond Jr, KB Bjugstad, YD Teng, V Ourednik, J Ourednik, ... Proceedings of the National Academy of Sciences 104 (29), 12175-12180, 2007 | 432 | 2007 |
Cryopreservation maintains functionality of human iPSC dopamine neurons and rescues parkinsonian phenotypes in vivo DR Wakeman, BM Hiller, DJ Marmion, CW McMahon, GT Corbett, ... Stem cell reports 9 (1), 149-161, 2017 | 85 | 2017 |
Cell transplantation and gene therapy in Parkinson's disease DR Wakeman, HB Dodiya, JH Kordower Mount Sinai Journal of Medicine: A Journal of Translational and Personalized …, 2011 | 71 | 2011 |
Microarray-based transcriptional and epigenetic profiling of matrix metalloproteinases, collagens, and related genes in cancer AV Chernov, S Baranovskaya, VS Golubkov, DR Wakeman, EY Snyder, ... Journal of Biological Chemistry 285 (25), 19647-19659, 2010 | 63 | 2010 |
Adhesive interactions between human neural stem cells and inflamed human vascular endothelium are mediated by integrins FJ Mueller, N Serobyan, IU Schraufstatter, R DiScipio, D Wakeman, ... Stem cells 24 (11), 2367-2372, 2006 | 62 | 2006 |
Functional multipotency of stem cells: a conceptual review of neurotrophic factor-based evidence and its role in translational research Y D Teng, D Yu, A E Ropper, J Li, S Kabatas, D R Wakeman, J Wang, ... Current neuropharmacology 9 (4), 574-585, 2011 | 58 | 2011 |
Human neural stem cells survive long term in the midbrain of dopamine-depleted monkeys after GDNF overexpression and project neurites toward an appropriate target DR Wakeman, DE Redmond Jr, HB Dodiya, JR Sladek Jr, C Leranth, ... Stem cells translational medicine 3 (6), 692-701, 2014 | 55 | 2014 |
Peripheral alpha‐synuclein and Parkinson's disease CW Olanow, DR Wakeman, JH Kordower Movement Disorders 29 (8), 963-966, 2014 | 50 | 2014 |
The future of GDNF in Parkinson's disease FP Manfredsson, NK Polinski, T Subramanian, N Boulis, DR Wakeman, ... Frontiers in aging neuroscience 12, 593572, 2020 | 44 | 2020 |
Neonatal immune-tolerance in mice does not prevent xenograft rejection VB Mattis, DR Wakeman, C Tom, HB Dodiya, SY Yeung, AH Tran, ... Experimental neurology 254, 90-98, 2014 | 37 | 2014 |
Large animal models are critical for rationally advancing regenerative therapies DR Wakeman, AM Crain, EY Snyder Regenerative medicine 1 (4), 405-413, 2006 | 37 | 2006 |
Survival and integration of neurons derived from human embryonic stem cells in MPTP-lesioned primates DR Wakeman, S Weiss, JR Sladek Jr, JD Elsworth, B Bauereis, C Leranth, ... Cell transplantation 23 (8), 981-994, 2014 | 29 | 2014 |
Cellular repair in the parkinsonian nonhuman primate brain DE Redmond Jr, S Weiss, JD Elsworth, RH Roth, DR Wakeman, ... Rejuvenation Research 13 (2-3), 188-194, 2010 | 29 | 2010 |
Culture system for rodent and human oligodendrocyte specification, lineage progression, and maturation A Espinosa‐Jeffrey, DR Wakeman, SU Kim, EY Snyder, J de Vellis Current protocols in stem cell biology 10 (1), 2D. 4.1-2D. 4.26, 2009 | 29 | 2009 |
Mitomycin-C treatment during differentiation of induced pluripotent stem cell-derived dopamine neurons reduces proliferation without compromising survival or function in vivo BM Hiller, DJ Marmion, RM Gross, CA Thompson, CA Chavez, P Brundin, ... Stem cells translational medicine 10 (2), 278-290, 2021 | 20 | 2021 |
Long‐term multilayer adherent network (MAN) expansion, maintenance, and characterization, chemical and genetic manipulation, and transplantation of human fetal forebrain neural … DR Wakeman, MR Hofmann, DE Redmond Jr, YD Teng, EY Snyder Current Protocols in Stem Cell Biology 9 (1), 2D. 3.1-2D. 3.77, 2009 | 18 | 2009 |
Chemical mutagenesis of a GPCR ligand: Detoxifying “inflammo-attraction” to direct therapeutic stem cell migration JP Lee, R Zhang, M Yan, S Duggineni, DR Wakeman, WL Niles, Y Feng, ... Proceedings of the National Academy of Sciences 117 (49), 31177-31188, 2020 | 12 | 2020 |
Intrathecal amyloid‐beta oligomer administration increases tau phosphorylation in the medial temporal lobe in the African green monkey: A nonhuman primate model of Alzheimer's … DR Wakeman, MR Weed, SE Perez, EN Cline, KL Viola, KC Wilcox, ... Neuropathology and applied neurobiology 48 (4), e12800, 2022 | 11 | 2022 |
Homing of neural stem cells from the venous compartment into a brain infarct does not involve conventional interactions with vascular endothelium V Goncharova, S Das, W Niles, I Schraufstatter, AK Wong, T Povaly, ... Stem cells translational medicine 3 (2), 229-240, 2014 | 11 | 2014 |