Bismuth antimicrobial drugs serve as broad-spectrum metallo-β-lactamase inhibitors R Wang, TP Lai, P Gao, H Zhang, PL Ho, PCY Woo, G Ma, RYT Kao, H Li, ... Nature communications 9 (1), 439, 2018 | 229 | 2018 |
HKOCl-3: a fluorescent hypochlorous acid probe for live-cell and in vivo imaging and quantitative application in flow cytometry and a 96-well microplate assay JJ Hu, NK Wong, MY Lu, X Chen, S Ye, AQ Zhao, P Gao, RYT Kao, ... Chemical science 7 (3), 2094-2099, 2016 | 149 | 2016 |
Multi-target mode of action of silver against Staphylococcus aureus endows it with capability to combat antibiotic resistance H Wang, M Wang, X Xu, P Gao, Z Xu, Q Zhang, H Li, A Yan, RYT Kao, ... Nature communications 12 (1), 3331, 2021 | 129 | 2021 |
Suppression of Staphylococcus aureus virulence by a small-molecule compound P Gao, PL Ho, B Yan, KH Sze, J Davies, RYT Kao Proceedings of the National Academy of Sciences 115 (31), 8003-8008, 2018 | 57 | 2018 |
Dehydrosqualene Desaturase as a Novel Target for Anti-Virulence Therapy against Staphylococcus aureus P Gao, J Davies, RYT Kao MBio 8 (5), 10.1128/mbio. 01224-17, 2017 | 53 | 2017 |
Natural products triptolide, celastrol, and withaferin A inhibit the chaperone activity of peroxiredoxin I Q Zhao, Y Ding, Z Deng, OY Lee, P Gao, P Chen, RJ Rose, H Zhao, ... Chemical science 6 (7), 4124-4130, 2015 | 51 | 2015 |
A discovery of novel Mycobacterium tuberculosis pantothenate synthetase inhibitors based on the molecular mechanism of actinomycin D inhibition Y Yang, P Gao, Y Liu, X Ji, M Gan, Y Guan, X Hao, Z Li, C Xiao Bioorganic & medicinal chemistry letters 21 (13), 3943-3946, 2011 | 42 | 2011 |
Methylation of daptomycin leading to the discovery of kynomycin, a cyclic lipodepsipeptide active against resistant pathogens HY Chow, KHL Po, P Gao, P Blasco, X Wang, C Li, L Ye, K Jin, K Chen, ... Journal of Medicinal Chemistry 63 (6), 3161-3171, 2020 | 33 | 2020 |
Identification and validation of a novel lead compound targeting 4-diphosphocytidyl-2-C-methylerythritol synthetase (IspD) of mycobacteria P Gao, Y Yang, C Xiao, Y Liu, M Gan, Y Guan, X Hao, J Meng, S Zhou, ... European journal of pharmacology 694 (1-3), 45-52, 2012 | 30 | 2012 |
A tailored positively-charged hydrophobic surface reduces the risk of implant associated infections J Shen, P Gao, S Han, RYT Kao, S Wu, X Liu, S Qian, PK Chu, ... Acta Biomaterialia 114, 421-430, 2020 | 27 | 2020 |
Adenosine synthase A contributes to recurrent Staphylococcus aureus infection by dampening protective immunity J Deng, B Zhang, H Chu, X Wang, Y Wang, HR Gong, R Li, D Yang, C Li, ... EBioMedicine 70, 2021 | 17 | 2021 |
Construction of a Multiplex Promoter Reporter Platform to Monitor Staphylococcus aureus Virulence Gene Expression and the Identification of Usnic Acid as a Potent … P Gao, Y Wang, I Villanueva, PL Ho, J Davies, RYT Kao Frontiers in microbiology 7, 1344, 2016 | 13 | 2016 |
Subinhibitory concentrations of antibiotics exacerbate staphylococcal infection by inducing bacterial virulence P Gao, Y Wei, RE Wan, KW Wong, HTV Iu, SSC Tai, Y Li, HCB Yam, ... Microbiology Spectrum 10 (4), e00640-22, 2022 | 9 | 2022 |
Broad and effective protection against Staphylococcus aureus is elicited by a multivalent vaccine formulated with novel antigens J Deng, X Wang, BZ Zhang, P Gao, Q Lin, RYT Kao, K Gustafsson, ... Msphere 4 (5), 10.1128/msphere. 00362-19, 2019 | 9 | 2019 |
Isolation, purification, identification of structure and study of bioactivity of anti-TB active component 9005B Z Zhang, P Gao, Y Guan, CL Xiao, XQ Hao Chinese Journal of Antibiotics, 2009 | 9 | 2009 |
Digging Deeper to Save the Old Anti-Tuberculosis Target: D-Alanine–D-Alanine Ligase with a Novel Inhibitor, IMB-0283 J Meng, P GAO, X Wang, Y Guan, Y Liu, C Xiao Frontiers in Microbiology 10, 3017, 2020 | 7 | 2020 |
Linoleic acid metabolism activation in macrophages promotes the clearing of intracellular Staphylococcus aureus B Yan, K Fung, S Ye, PM Lai, YX Wei, KH Sze, D Yang, P Gao, RY Kao Chemical Science 13, 12445-12460, 2022 | 6 | 2022 |
Screening repurposed antiviral small molecules as antimycobacterial compounds by a lux-based phoP promoter-reporter platform L Zhu, AWT Lee, KKL Wu, P Gao, KKG Tam, R Rajwani, GC Chaburte, ... Antibiotics 11 (3), 369, 2022 | 5 | 2022 |
Antivirulence Agent as an Adjuvant of β-Lactam Antibiotics in Treating Staphylococcal Infections P Gao, Y Wei, SSC Tai, P Halebeedu Prakash, HTV Iu, Y Li, HCB Yam, ... s Note: MDPI stays neu-tral with regard to jurisdictional claims in …, 2022 | 3 | 2022 |
A cell-based screening system for detection of inhibitors toward mycobacterial cell wall core P Gao, Y Guan, D Song, C Xiao The Journal of Antibiotics 62 (6), 315-318, 2009 | 3 | 2009 |