Alopecia areata is driven by cytotoxic T lymphocytes and is reversed by JAK inhibition L Xing, Z Dai, A Jabbari, JE Cerise, CA Higgins, W Gong, A De Jong, ... Nature medicine 20 (9), 1043-1049, 2014 | 909 | 2014 |
Microenvironmental reprogramming by three-dimensional culture enables dermal papilla cells to induce de novo human hair-follicle growth CA Higgins, JC Chen, JE Cerise, CAB Jahoda, AM Christiano Proceedings of the National Academy of Sciences 110 (49), 19679-19688, 2013 | 356 | 2013 |
Generation of 3D skin equivalents fully reconstituted from human induced pluripotent stem cells (iPSCs) M Itoh, N Umegaki-Arao, Z Guo, L Liu, CA Higgins, AM Christiano PloS one 8 (10), e77673, 2013 | 245 | 2013 |
Pharmacologic inhibition of JAK-STAT signaling promotes hair growth S Harel, CA Higgins, JE Cerise, Z Dai, JC Chen, R Clynes, AM Christiano Science Advances 1 (9), e1500973, 2015 | 219 | 2015 |
Hydrogel-coated microneedle arrays for minimally invasive sampling and sensing of specific circulating nucleic acids from skin interstitial fluid D Al Sulaiman, JYH Chang, NR Bennett, H Topouzi, CA Higgins, DJ Irvine, ... ACS nano 13 (8), 9620-9628, 2019 | 169 | 2019 |
FGF5 is a crucial regulator of hair length in humans CA Higgins, L Petukhova, S Harel, YY Ho, E Drill, L Shapiro, M Wajid, ... Proceedings of the National Academy of Sciences 111 (29), 10648-10653, 2014 | 154 | 2014 |
Modelling the hair follicle dermal papilla using spheroid cell cultures CA Higgins, GD Richardson, D Ferdinando, GE Westgate, CAB Jahoda Experimental dermatology 19 (6), 546-548, 2010 | 136 | 2010 |
From telogen to exogen: mechanisms underlying formation and subsequent loss of the hair club fiber CA Higgins, GE Westgate, CAB Jahoda Journal of Investigative Dermatology 129 (9), 2100-2108, 2009 | 131 | 2009 |
Melanin transfer in human 3D skin equivalents generated exclusively from induced pluripotent stem cells K Gledhill, Z Guo, N Umegaki-Arao, CA Higgins, M Itoh, AM Christiano PloS one 10 (8), e0136713, 2015 | 107 | 2015 |
Mechanotransduction in osteogenesis S Stewart, A Darwood, S Masouros, C Higgins, A Ramasamy Bone & joint research 9 (1), 1-14, 2020 | 82 | 2020 |
Methods for the isolation and 3D culture of dermal papilla cells from human hair follicles H Topouzi, NJ Logan, G Williams, CA Higgins Experimental dermatology 26 (6), 491-496, 2017 | 73 | 2017 |
Generation and characterization of multipotent stem cells from established dermal cultures RP Hill, K Gledhill, A Gardner, CA Higgins, H Crawford, C Lawrence, ... PLoS One 7 (11), e50742, 2012 | 60 | 2012 |
Subpopulations of dermal skin fibroblasts secrete distinct extracellular matrix: implications for using skin substitutes in the clinic M Ghetti, H Topouzi, G Theocharidis, V Papa, G Williams, E Bondioli, ... British Journal of Dermatology 179 (2), 381-393, 2018 | 53 | 2018 |
Morphology and composition play distinct and complementary roles in the tolerance of plantar skin to mechanical load CJ Boyle, M Plotczyk, SF Villalta, S Patel, S Hettiaratchy, SD Masouros, ... Science advances 5 (10), eaay0244, 2019 | 48 | 2019 |
Multifaceted role of hair follicle dermal cells in bioengineered skins CA Higgins, MF Roger, RP Hill, AS Ali‐Khan, JA Garlick, AM Christiano, ... British Journal of Dermatology 176 (5), 1259-1269, 2017 | 46 | 2017 |
Building a microphysiological skin model from induced pluripotent stem cells Z Guo, CA Higgins, BM Gillette, M Itoh, N Umegaki, K Gledhill, SK Sia, ... Stem cell research & therapy 4, 1-7, 2013 | 44 | 2013 |
The hair follicle: an underutilized source of cells and materials for regenerative medicine MT Kiani, CA Higgins, BD Almquist ACS biomaterials science & engineering 4 (4), 1193-1207, 2017 | 41 | 2017 |
Immune cell regulation of the hair cycle ECE Wang, CA Higgins Experimental dermatology 29 (3), 322-333, 2020 | 38 | 2020 |
Reprogramming of human hair follicle dermal papilla cells into induced pluripotent stem cells CA Higgins, M Itoh, K Inoue, GD Richardson, CAB Jahoda, AM Christiano The Journal of investigative dermatology 132 (6), 1725, 2012 | 36 | 2012 |
Regenerative medicine and hair loss: how hair follicle culture has advanced our understanding of treatment options for androgenetic alopecia CA Higgins, AM Christiano Regenerative medicine 9 (1), 101-111, 2014 | 35 | 2014 |