PRC2 facilitates the regulatory topology required for poised enhancer function during pluripotent stem cell differentiation S Cruz-Molina, P Respuela, C Tebartz, P Kolovos, M Nikolic, R Fueyo, ... Cell stem cell 20 (5), 689-705. e9, 2017 | 245 | 2017 |
Butyrate mediates decrease of histone acetylation centered on transcription start sites and down-regulation of associated genes A Rada-Iglesias, S Enroth, A Ameur, CM Koch, GK Clelland, ... Genome research 17 (6), 708-719, 2007 | 188 | 2007 |
Histone acetylation and methylation at sites initiating divergent polycistronic transcription in Trypanosoma cruzi P Respuela, M Ferella, A Rada-Iglesias, L Åslund Journal of Biological Chemistry 283 (23), 15884-15892, 2008 | 127 | 2008 |
Foxd3 promotes exit from naive pluripotency through enhancer decommissioning and inhibits germline specification P Respuela, M Nikolić, M Tan, P Frommolt, Y Zhao, J Wysocka, ... Cell stem cell 18 (1), 118-133, 2016 | 87 | 2016 |
Orphan CpG islands amplify poised enhancer regulatory activity and determine target gene responsiveness T Pachano, V Sánchez-Gaya, T Ealo, M Mariner-Faulí, T Bleckwehl, ... Nature genetics 53 (7), 1036-1049, 2021 | 80 | 2021 |
The Short Non-Coding Transcriptome of the Protozoan Parasite Trypanosoma cruzi O Franzen, E Arner, M Ferella, D Nilsson, P Respuela, P Carninci, ... PLoS neglected tropical diseases 5 (8), e1283, 2011 | 61 | 2011 |
Enhancer-associated H3K4 methylation safeguards in vitro germline competence T Bleckwehl, G Crispatzu, K Schaaf, P Respuela, M Bartusel, L Benson, ... Nature Communications 12 (1), 5771, 2021 | 41 | 2021 |
Orphan CpG islands boost the regulatory activity of poised enhancers and dictate the responsiveness of their target genes T Pachano, V Sánchez-Gaya, M Mariner-Faulí, T Ealo, HG Asenjo, ... biorxiv, 2020.08. 05.237768, 2020 | 8 | 2020 |
Characterization of a Trypanosoma cruzi acetyltransferase: cellular location, activity and structure S Ochaya, P Respuela, M Simonsson, A Saraswathi, C Branche, J Lee, ... Molecular and biochemical parasitology 152 (2), 123-131, 2007 | 7 | 2007 |
Synergistic insulation of regulatory domains by developmental genes and clusters of CTCF sites T Ealo, V Sanchez-Gaya, P Respuela, MMS Martín, E Martin-Batista, ... bioRxiv, 2023.12. 15.571760, 2023 | 6 | 2023 |
Cooperative insulation of regulatory domains by CTCF-dependent physical insulation and promoter competition T Ealo, V Sanchez-Gaya, P Respuela, M Muñoz-San Martín, ... Nature Communications 15 (1), 7258, 2024 | 2 | 2024 |
Enhancer Remodeling During Early Mammalian Embryogenesis: Lessons for Somatic Reprogramming, Rejuvenation, and Aging P Respuela, A Rada-Iglesias Current Stem Cell Reports 2, 263-272, 2016 | 1 | 2016 |
DNA methylation patterns in the parasite Trypanosoma cruzi P Respuela, M Ferella, L Åslund | | 2009 |
Characterization of a Trypanosoma cruzi polypyrimidine tract binding protein interacting with single-stranded forming DNA P Respuela, AN Tran, I D’Orso, AM Nyström, L Åslund | | 2009 |
Distinct histone modification profiles at transcription start sites during development of the parasite Trypanosoma cruzi. P Respuela, M Ferella, L Åslund | | 2009 |
Gene Regulation and Epigenetic Mechanisms in the Parasite Trypanosoma cruzi P Respuela Acta Universitatis Upsaliensis, 2009 | | 2009 |