The different roles of ER subtypes in cancer biology and therapy C Thomas, JÅ Gustafsson Nature Reviews Cancer 11 (8), 597-608, 2011 | 801 | 2011 |
ERβ1 represses basal-like breast cancer epithelial to mesenchymal transition by destabilizing EGFR C Thomas, G Rajapaksa, F Nikolos, R Hao, A Katchy, CW McCollum, ... Breast cancer research 14, 1-15, 2012 | 113 | 2012 |
Pharmaceutical agents known to produce disulfiram-like reaction: effects on hepatic ethanol metabolism and brain monoamines PN Karamanakos, P Pappas, VA Boumba, C Thomas, M Malamas, ... International journal of toxicology 26 (5), 423-432, 2007 | 106 | 2007 |
Estrogen receptor mutations and functional consequences for breast cancer C Thomas, JÅ Gustafsson Trends in Endocrinology & Metabolism 26 (9), 467-476, 2015 | 97 | 2015 |
Estrogen-dependent DLL1-mediated Notch signaling promotes luminal breast cancer S Kumar, DW Srivastav RK, Wilkes, R Taylor, S Kim, J Kowalski, S Chatla, ... Oncogene, 2018 | 78 | 2018 |
The two-pore domain potassium channel KCNK5: induction by estrogen receptor α and role in proliferation of breast cancer cells CP Alvarez-Baron, P Jonsson, C Thomas, SE Dryer, C Williams Molecular Endocrinology 25 (8), 1326-1336, 2011 | 68 | 2011 |
Estrogen receptor beta decreases survival of p53-defective cancer cells after DNA damage by impairing G2/M checkpoint signaling CG Thomas, A Strom, K Lindberg, JA Gustafsson Breast cancer research and treatment 127, 417-427, 2011 | 64 | 2011 |
ERβ decreases breast cancer cell survival by regulating the IRE1/XBP-1 pathway G Rajapaksa, F Nikolos, I Bado, R Clarke, JÅ Gustafsson, C Thomas Oncogene 34 (31), 4130-4141, 2015 | 57 | 2015 |
ERβ decreases the invasiveness of triple-negative breast cancer cells by regulating mutant p53 oncogenic function I Bado, F Nikolos, G Rajapaksa, JÅ Gustafsson, C Thomas Oncotarget 7 (12), 13599, 2016 | 53 | 2016 |
ERdj5 sensitizes neuroblastoma cells to endoplasmic reticulum stress-induced apoptosis CG Thomas, G Spyrou Journal of Biological Chemistry 284 (10), 6282-6290, 2009 | 51 | 2009 |
Bcl-2 blocks 2-methoxyestradiol induced leukemia cell apoptosis by a p27Kip1-dependent G1/S cell cycle arrest in conjunction with NF-κB activation C Batsi, S Markopoulou, E Kontargiris, C Charalambous, C Thomas, ... Biochemical pharmacology 78 (1), 33-44, 2009 | 50 | 2009 |
Vitamin C transiently arrests cancer cell cycle progression in S phase and G2/M boundary by modulating the kinetics of activation and the subcellular localization of … CG Thomas, PE Vezyraki, VP Kalfakakou, AM Evangelou Journal of cellular physiology 205 (2), 310-318, 2005 | 37 | 2005 |
Estrogen signaling and unfolded protein response in breast cancer G Rajapaksa, C Thomas, JÅ Gustafsson The Journal of steroid biochemistry and molecular biology 163, 45-50, 2016 | 34 | 2016 |
Progesterone receptor-estrogen receptor crosstalk: a novel insight C Thomas, JÅ Gustafsson Trends in Endocrinology & Metabolism 26 (9), 453-454, 2015 | 33 | 2015 |
Rosmarinic acid failed to suppress hydrogen peroxide-mediated apoptosis but induced apoptosis of Jurkat cells which was suppressed by Bcl-2 E Kolettas, C Thomas, E Leneti, I Skoufos, C Mbatsi, C Sisoula, G Manos, ... Molecular and cellular biochemistry 285, 111-120, 2006 | 31 | 2006 |
Somatic loss of estrogen receptor beta and p53 synergize to induce breast tumorigenesis I Bado, F Nikolos, G Rajapaksa, W Wu, J Castaneda, S Krishnamurthy, ... Breast Cancer Research 19, 1-10, 2017 | 28 | 2017 |
Combination of CHEK1/2 inhibition and ionizing radiation results in abscopal tumor response through increased micronuclei formation HH Chao, IV Karagounis, C Thomas, NB François, A Facciabene, ... Oncogene 39 (22), 4344-4357, 2020 | 27 | 2020 |
ERβ regulates NSCLC phenotypes by controlling oncogenic RAS signaling F Nikolos, C Thomas, G Rajapaksa, I Bado, JÅ Gustafsson Molecular Cancer Research 12 (6), 843-854, 2014 | 27 | 2014 |
Targeting PES1 for restoring the ERα/ERβ ratio in breast cancer C Thomas, JÅ Gustafsson The Journal of Clinical Investigation 122 (8), 2012 | 23 | 2012 |
Dll1-mediated notch signaling drives tumor cell cross-talk with cancer-associated fibroblasts to promote radioresistance in breast cancer A Nandi, R Debnath, A Nayak, TKJ To, G Thacker, M Reilly, S Gumber, ... Cancer research 82 (20), 3718-3733, 2022 | 21 | 2022 |