The two allele sequences of a common polymorphism in the promoter of the plasminogen activator inhibitor-1 (PAI-1) gene respond differently to interleukin-1 in HepG2 cells SJ Dawson, B Wiman, A Hamsten, F Green, S Humphries, AM Henney Journal of Biological Chemistry 268 (15), 10739-10745, 1993 | 837 | 1993 |
Genetic variation at the plasminogen activator inhibitor-1 locus is associated with altered levels of plasma plasminogen activator inhibitor-1 activity. S Dawson, A Hamsten, B Wiman, A Henney, S Humphries Arteriosclerosis and thrombosis: a journal of vascular biology 11 (1), 183-190, 1991 | 447 | 1991 |
The 4G/5G genetic polymorphism in the promoter of the plasminogen activator inhibitor-1 (PAI-1) gene is associated with differences in plasma PAI-1 activity but not with risk … S Ye, FR Green, PY Scarabin, V Nicaud, L Bara, SJ Dawson, ... Thrombosis and haemostasis 74 (09), 837-841, 1995 | 323 | 1995 |
The status of PAI-1 as a risk factor for arterial and thrombotic disease: a review S Dawson, A Henney Atherosclerosis 95 (2-3), 105-117, 1992 | 296 | 1992 |
Age-related hearing loss MR Bowl, SJ Dawson Cold Spring Harbor perspectives in medicine 9 (8), a033217, 2019 | 265 | 2019 |
Activation of fibroblast procollagen α1 (I) transcription by mechanical strain is transforming growth factor-β-dependent and involves increased binding of CCAAT-binding factor … GE Lindahl, RC Chambers, J Papakrivopoulou, SJ Dawson, ... Journal of Biological Chemistry 277 (8), 6153-6161, 2002 | 155 | 2002 |
GWAS identifies 44 independent associated genomic loci for self-reported adult hearing difficulty in UK Biobank HRR Wells, MB Freidin, FNZ Abidin, A Payton, P Dawes, KJ Munro, ... The American Journal of Human Genetics 105 (4), 788-802, 2019 | 139 | 2019 |
Fibrinogen, factor VII and PAI-1 genotypes and the risk of coronary and peripheral atherosclerosis: Edinburgh Artery Study AJ Lee, FGR Fowkes, GDO Lowe, JM Connor, A Rumley Thrombosis and haemostasis 81 (04), 553-560, 1999 | 125 | 1999 |
The epidemiology of otosclerosis in a British cohort M Crompton, BA Cadge, JL Ziff, AJ Mowat, R Nash, JA Lavy, HRF Powell, ... Otology & Neurotology 40 (1), 22-30, 2019 | 104 | 2019 |
Genetic variation on chromosome 16 is associated with abdominal aortic aneurysm JT Powell, A Bashir, S Dawson, N Vine, AM Henney, SE Humphries, ... Clinical Science 78 (1), 13-16, 1990 | 100 | 1990 |
The mouse as a model for age-related hearing loss-a mini-review MR Bowl, SJ Dawson Gerontology 61 (2), 149-157, 2015 | 98 | 2015 |
transcription by mechanical strain is transforming growth factor-beta-dependent and involves increased binding of CCAAT-binding factor (CBF/NF-Y) at the proximal promoter GE Lindahl, RC Chambers, J Papakrivopoulou, SJ Dawson, ... J Biol Chem 277 (8), 6153-6161, 2002 | 98 | 2002 |
Mouse screen reveals multiple new genes underlying mouse and human hearing loss NJ Ingham, SA Pearson, VE Vancollie, V Rook, MA Lewis, J Chen, ... PLoS biology 17 (4), e3000194, 2019 | 94 | 2019 |
High-frequency audiometry reveals high prevalence of aminoglycoside ototoxicity in children with cystic fibrosis G Al-Malky, SJ Dawson, T Sirimanna, E Bagkeris, R Suri Journal of Cystic Fibrosis 14 (2), 248-254, 2015 | 91 | 2015 |
A common 4G allele in the promoter of the plasminogen activator inhibitor-1 (PAI-1) gene as a risk factor for pulmonary embolism and arterial thrombosis in hereditary protein S … B Zöller, PG de Frutos, B Dahlbäck Thrombosis and haemostasis 79 (04), 802-807, 1998 | 89 | 1998 |
The Brn-3a transcription factor induces neuronal process outgrowth and the coordinate expression of genes encoding synaptic proteins MD Smith, SJ Dawson, DS Latchman Molecular and cellular biology 17 (1), 345-354, 1997 | 80 | 1997 |
Estrogen-related receptor gamma and hearing function: evidence of a role in humans and mice LS Nolan, H Maier, I Hermans-Borgmeyer, G Girotto, R Ecob, N Pirastu, ... Neurobiology of aging 34 (8), 2077. e1-2077. e9, 2013 | 78 | 2013 |
The DFNA15 deafness mutation affects POU4F3 protein stability, localization, and transcriptional activity S Weiss, I Gottfried, I Mayrose, SL Khare, M Xiang, SJ Dawson, ... Molecular and cellular biology 23 (22), 7957-7964, 2003 | 71 | 2003 |
Coordinate induction of the three neurofilament genes by the Brn-3a transcription factor MD Smith, PJ Morris, SJ Dawson, ML Schwartz, WW Schlaepfer, ... Journal of Biological Chemistry 272 (34), 21325-21333, 1997 | 62 | 1997 |
Whole exome sequencing in adult-onset hearing loss reveals a high load of predicted pathogenic variants in known deafness-associated genes and identifies new candidate genes MA Lewis, LS Nolan, BA Cadge, LJ Matthews, BA Schulte, JR Dubno, ... BMC medical genomics 11, 1-12, 2018 | 61 | 2018 |