| A cross-population atlas of genetic associations for 220 human phenotypes S Sakaue, M Kanai, Y Tanigawa, J Karjalainen, M Kurki, S Koshiba, ... Nature genetics 53 (10), 1415-1424, 2021 | 1060 | 2021 |
| Suppression of autophagic activity by Rubicon is a signature of aging S Nakamura, M Oba, M Suzuki, A Takahashi, T Yamamuro, M Fujiwara, ... Nature communications 10 (1), 847, 2019 | 180 | 2019 |
| Multi-ancestry genome-wide association analyses identify novel genetic mechanisms in rheumatoid arthritis K Ishigaki, S Sakaue, C Terao, Y Luo, K Sonehara, K Yamaguchi, ... Nature genetics 54 (11), 1640-1651, 2022 | 162 | 2022 |
| LC3 lipidation is essential for TFEB activation during the lysosomal damage response to kidney injury S Nakamura, S Shigeyama, S Minami, T Shima, S Akayama, T Matsuda, ... Nature cell biology 22 (10), 1252-1263, 2020 | 156 | 2020 |
| A high-resolution HLA reference panel capturing global population diversity enables multi-ancestry fine-mapping in HIV host response Y Luo, M Kanai, W Choi, X Li, S Sakaue, K Yamamoto, K Ogawa, ... Nature genetics 53 (10), 1504-1516, 2021 | 116 | 2021 |
| Genetic and phenotypic landscape of the major histocompatibilty complex region in the Japanese population J Hirata, K Hosomichi, S Sakaue, M Kanai, H Nakaoka, K Ishigaki, ... Nature genetics 51 (3), 470-480, 2019 | 93 | 2019 |
| DOCK2 is involved in the host genetics and biology of severe COVID-19 H Namkoong, R Edahiro, T Takano, H Nishihara, Y Shirai, K Sonehara, ... Nature 609 (7928), 754-760, 2022 | 64 | 2022 |
| Metagenome-wide association study revealed disease-specific landscape of the gut microbiome of systemic lupus erythematosus in Japanese Y Tomofuji, Y Maeda, E Oguro-Igashira, T Kishikawa, K Yamamoto, ... Annals of the Rheumatic Diseases 80 (12), 1575-1583, 2021 | 58 | 2021 |
| Whole gut virome analysis of 476 Japanese revealed a link between phage and autoimmune disease Y Tomofuji, T Kishikawa, Y Maeda, K Ogawa, T Nii, T Okuno, ... Annals of the rheumatic diseases 81 (2), 278-288, 2022 | 54 | 2022 |
| Integration of genetics and miRNA–target gene network identified disease biology implicated in tissue specificity S Sakaue, J Hirata, Y Maeda, E Kawakami, T Nii, T Kishikawa, K Ishigaki, ... Nucleic acids research 46 (22), 11898-11909, 2018 | 45 | 2018 |
| A metagenome-wide association study of gut microbiome in patients with multiple sclerosis revealed novel disease pathology T Kishikawa, K Ogawa, D Motooka, A Hosokawa, M Kinoshita, K Suzuki, ... Frontiers in cellular and infection microbiology 10, 585973, 2020 | 36 | 2020 |
| Genetic and phenotypic landscape of the mitochondrial genome in the Japanese population K Yamamoto, S Sakaue, K Matsuda, Y Murakami, Y Kamatani, K Ozono, ... Communications Biology 3 (1), 104, 2020 | 31 | 2020 |
| Genetic determinants of risk in autoimmune pulmonary alveolar proteinosis S Sakaue, E Yamaguchi, Y Inoue, M Takahashi, J Hirata, K Suzuki, S Ito, ... Nature communications 12 (1), 1032, 2021 | 30 | 2021 |
| A global atlas of genetic associations of 220 deep phenotypes S Sakaue, M Kanai, Y Tanigawa, J Karjalainen, M Kurki, S Koshiba, ... MedRxiv, 2020.10. 23.20213652, 2020 | 25 | 2020 |
| Genetic architecture of microRNA expression and its link to complex diseases in the Japanese population K Sonehara, S Sakaue, Y Maeda, J Hirata, T Kishikawa, K Yamamoto, ... Human molecular genetics 31 (11), 1806-1820, 2022 | 22 | 2022 |
| Large-scale plasma-metabolome analysis identifies potential biomarkers of psoriasis and its clinical subtypes T Kishikawa, N Arase, S Tsuji, Y Maeda, T Nii, J Hirata, K Suzuki, ... Journal of Dermatological Science 102 (2), 78-84, 2021 | 21 | 2021 |
| The whole blood transcriptional regulation landscape in 465 COVID-19 infected samples from Japan COVID-19 Task Force QS Wang, R Edahiro, H Namkoong, T Hasegawa, Y Shirai, K Sonehara, ... Nature communications 13 (1), 4830, 2022 | 20 | 2022 |
| Prokaryotic and viral genomes recovered from 787 Japanese gut metagenomes revealed microbial features linked to diets, populations, and diseases Y Tomofuji, T Kishikawa, Y Maeda, K Ogawa, Y Otake-Kasamoto, ... Cell Genomics 2 (12), 2022 | 16 | 2022 |
| Whole genome sequence analyses of eGFR in 23,732 people representing multiple ancestries in the NHLBI trans-omics for precision medicine (TOPMed) consortium BM Lin, KE Grinde, JA Brody, CE Breeze, LM Raffield, JC Mychaleckyj, ... EBioMedicine 63, 2021 | 16 | 2021 |
| Genotype–phenotype analysis, and assessment of the importance of the zinc-binding site in PHEX in Japanese patients with X-linked hypophosphatemic rickets using 3D structure … Y Ishihara, Y Ohata, S Takeyari, T Kitaoka, M Fujiwara, Y Nakano, ... Bone 153, 116135, 2021 | 15 | 2021 |
Yukinori OkadaProfessor, Osaka University, Japan在 broadinstitute.org 的电子邮件经过验证
