Exome sequencing in amyotrophic lateral sclerosis identifies risk genes and pathways ET Cirulli, BN Lasseigne, S Petrovski, PC Sapp, PA Dion, CS Leblond, ... Science 347 (6229), 1436-1441, 2015 | 1012 | 2015 |
Exome sequencing in amyotrophic lateral sclerosis identifies risk genes and pathways ET Cirulli, BN Lasseigne, S Petrovski, PC Sapp, PA Dion, CS Leblond, ... Science 347 (6229), 1436-1441, 2015 | 1012 | 2015 |
Genome-wide analyses identify KIF5A as a novel ALS gene A Nicolas, KP Kenna, AE Renton, N Ticozzi, F Faghri, R Chia, ... Neuron 97 (6), 1267-1288, 2018 | 609 | 2018 |
LARP7 is a stable component of the 7SK snRNP while P-TEFb, HEXIM1 and hnRNP A1 are reversibly associated BJ Krueger, C Jeronimo, BB Roy, A Bouchard, C Barrandon, SA Byers, ... Nucleic acids research 36 (7), 2219-2229, 2008 | 269 | 2008 |
The mechanism of release of P-TEFb and HEXIM1 from the 7SK snRNP by viral and cellular activators includes a conformational change in 7SK BJ Krueger, K Varzavand, JJ Cooper, DH Price PloS one 5 (8), e12335, 2010 | 138 | 2010 |
A KSHV microRNA directly targets G protein-coupled receptor kinase 2 to promote the migration and invasion of endothelial cells by inducing CXCR2 and activating AKT signaling M Hu, C Wang, W Li, W Lu, Z Bai, D Qin, Q Yan, J Zhu, BJ Krueger, ... PLoS pathogens 11 (9), e1005171, 2015 | 82 | 2015 |
Virus-Encoded MicroRNAs Facilitate Gammaherpesvirus Latency and Pathogenesis In Vivo ER Feldman, M Kara, CB Coleman, KR Grau, LM Oko, BJ Krueger, ... MBio 5 (3), 10.1128/mbio. 00981-14, 2014 | 74 | 2014 |
Epileptic encephalopathy-causing mutations in DNM1 impair synaptic vesicle endocytosis RS Dhindsa, SS Bradrick, X Yao, EL Heinzen, S Petrovski, BJ Krueger, ... Neurology: Genetics 1 (1), e4, 2015 | 57 | 2015 |
A KSHV microRNA enhances viral latency and induces angiogenesis by targeting GRK2 to activate the CXCR2/AKT pathway W Li, X Jia, C Shen, M Zhang, J Xu, Y Shang, K Zhu, M Hu, Q Yan, D Qin, ... Oncotarget 7 (22), 32286, 2016 | 51 | 2016 |
The SH3BGR/STAT3 pathway regulates cell migration and angiogenesis induced by a gammaherpesvirus microRNA W Li, Q Yan, X Ding, C Shen, M Hu, Y Zhu, D Qin, H Lu, BJ Krueger, ... PLoS pathogens 12 (4), e1005605, 2016 | 51 | 2016 |
Human mesenchymal stem cells of diverse origins support persistent infection with Kaposi’s sarcoma-associated herpesvirus and manifest distinct angiogenic, invasive, and … MS Lee, H Yuan, H Jeon, Y Zhu, S Yoo, S Shi, B Krueger, R Renne, C Lu, ... MBio 7 (1), 10.1128/mbio. 02109-15, 2016 | 48 | 2016 |
Kaposi’s sarcoma-associated herpesvirus (KSHV) induces the oncogenic miR-17-92 cluster and down-regulates TGF-β signaling HS Choi, V Jain, B Krueger, V Marshall, CH Kim, JL Shisler, D Whitby, ... PLoS pathogens 11 (11), e1005255, 2015 | 47 | 2015 |
KSHV miRNAs Decrease Expression of Lytic Genes in Latently Infected PEL and Endothelial Cells by Targeting Host Transcription Factors K Plaisance-Bonstaff, HS Choi, T Beals, BJ Krueger, IW Boss, LA Gay, ... Viruses 6 (10), 4005-4023, 2014 | 46 | 2014 |
The Drosophila 7SK snRNP and the essential role of dHEXIM in development D Nguyen, BJ Krueger, SC Sedore, JE Brogie, JT Rogers, TK Rajendra, ... Nucleic acids research 40 (12), 5283-5297, 2012 | 43 | 2012 |
A gammaherpesvirus noncoding RNA is essential for hematogenous dissemination and establishment of peripheral latency ER Feldman, M Kara, LM Oko, KR Grau, BJ Krueger, J Zhang, P Feng, ... MSphere 1 (2), 10.1128/msphere. 00105-15, 2016 | 36 | 2016 |
Identification of the physiological gene targets of the essential lytic replicative Kaposi's sarcoma-associated herpesvirus ORF57 protein D Verma, DJ Li, B Krueger, R Renne, S Swaminathan Journal of virology 89 (3), 1688-1702, 2015 | 36 | 2015 |
A Toolbox for Herpesvirus miRNA Research: Construction of a Complete Set of KSHV miRNA Deletion Mutants V Jain, K Plaisance-Bonstaff, R Sangani, C Lanier, A Dolce, J Hu, ... Viruses 8 (2), 54, 2016 | 35 | 2016 |
Clinical application of whole-genome sequencing in patients with primary immunodeficiency T Mousallem, TJ Urban, KM McSweeney, SE Kleinstein, M Zhu, M Adeli, ... Journal of Allergy and Clinical Immunology 136 (2), 476-479. e6, 2015 | 31 | 2015 |
A viral microRNA downregulates metastasis suppressor CD82 and induces cell invasion and angiogenesis by activating the c-Met signaling W Li, M Hu, C Wang, H Lu, F Chen, J Xu, Y Shang, F Wang, J Qin, Q Yan, ... Oncogene 36 (38), 5407-5420, 2017 | 30 | 2017 |
Exome sequencing results in successful riboflavin treatment of a rapidly progressive neurological condition S Petrovski, V Shashi, S Petrou, K Schoch, KM McSweeney, RS Dhindsa, ... Molecular Case Studies 1 (1), a000257, 2015 | 27 | 2015 |