Novel approach to inhibit asthma-mediated lung inflammation using anti-CD147 intervention WM Gwinn, JM Damsker, R Falahati, I Okwumabua, A Kelly-Welch, ... The Journal of Immunology 177 (7), 4870-4879, 2006 | 162 | 2006 |
Receptor‐stimulated oxidation of SHP‐2 promotes T‐cell adhesion through SLP‐76–ADAP J Kwon, CK Qu, JS Maeng, R Falahati, C Lee, MS Williams The EMBO journal 24 (13), 2331-2341, 2005 | 151 | 2005 |
AK002, a humanized sialic acid-binding immunoglobulin-like lectin-8 antibody that induces antibody-dependent cell-mediated cytotoxicity against human eosinophils and inhibits … BA Youngblood, EC Brock, J Leung, R Falahati, PJ Bryce, J Bright, ... International Archives of Allergy and Immunology 180 (2), 91-102, 2019 | 91 | 2019 |
Siglec-8 antibody reduces eosinophils and mast cells in a transgenic mouse model of eosinophilic gastroenteritis BA Youngblood, EC Brock, J Leung, R Falahati, BS Bochner, ... Jci Insight 4 (19), 2019 | 89 | 2019 |
Humanized mouse model of mast cell–mediated passive cutaneous anaphylaxis and passive systemic anaphylaxis PJ Bryce, R Falahati, LL Kenney, J Leung, C Bebbington, N Tomasevic, ... Journal of Allergy and Clinical Immunology 138 (3), 769-779, 2016 | 87 | 2016 |
Discovery, function, and therapeutic targeting of Siglec-8 BA Youngblood, J Leung, R Falahati, J Williams, J Schanin, EC Brock, ... Cells 10 (1), 19, 2020 | 64 | 2020 |
A monoclonal antibody to Siglec-8 suppresses non-allergic airway inflammation and inhibits IgE-independent mast cell activation J Schanin, S Gebremeskel, W Korver, R Falahati, M Butuci, TJ Haw, ... Mucosal immunology 14 (2), 366-376, 2021 | 63 | 2021 |
CD45‐associated protein promotes the response of primary CD4 T cells to low‐potency T‐cell receptor (TCR) stimulation and facilitates CD45 association with CD3/TCR and lck D Leitenberg, R Falahati, DD Lu, A Takeda Immunology 121 (4), 545-554, 2007 | 35 | 2007 |
Ganglioside‐exposed dendritic cells inhibit T‐cell effector function by promoting regulatory cell activity A Jales, R Falahati, E Mari, EJ Stemmy, W Shen, C Southammakosane, ... Immunology 132 (1), 134-143, 2011 | 33 | 2011 |
Changes in the role of the CD45 protein tyrosine phosphatase in regulating Lck tyrosine phosphorylation during thymic development R Falahati, D Leitenberg The Journal of Immunology 178 (4), 2056-2064, 2007 | 31 | 2007 |
Modulation of CD4 Th cell differentiation by ganglioside GD1a in vitro W Shen, R Falahati, R Stark, D Leitenberg, S Ladisch The Journal of Immunology 175 (8), 4927-4934, 2005 | 30 | 2005 |
Suppression of HLA expression by lentivirus-mediated gene transfer of siRNA cassettes and in vivo chemoselection to enhance hematopoietic stem cell transplantation K Hacke, R Falahati, L Flebbe-Rehwaldt, N Kasahara, KML Gaensler Immunologic research 44, 112-126, 2009 | 23 | 2009 |
Role of antigen-specific regulatory CD4+ CD25+ T cells in tolerance induction after neonatal IP administration of AAV-hF. IX Y Shi, R Falahati, J Zhang, L Flebbe-Rehwaldt, KML Gaensler Gene therapy 20 (10), 987-996, 2013 | 16 | 2013 |
Chemoselection of allogeneic HSC after murine neonatal transplantation without myeloablation or post-transplant immunosuppression R Falahati, J Zhang, L Flebbe-Rehwaldt, Y Shi, SL Gerson, KML Gaensler Molecular Therapy 20 (11), 2180-2189, 2012 | 15 | 2012 |
Selective regulation of TCR signaling pathways by the CD45 protein tyrosine phosphatase during thymocyte development R Falahati, D Leitenberg The Journal of Immunology 181 (9), 6082-6091, 2008 | 15 | 2008 |
Anti-Siglec-8 antibodies and methods of use thereof CR Bebbington, R Falahati, CRS Fernandes, DJ Matthews, N Tomasevic, ... US Patent 9,546,215, 2017 | 12 | 2017 |
Methods and compositions for treating fibrotic diseases CR Bebbington, N Tomasevic, R Falahati, BA Youngblood US Patent 10,774,145, 2020 | 4 | 2020 |
Methods and compositions for treating systemic mastocytosis CR Bebbington, N Tomasevic, R Falahati US Patent 10,604,577, 2020 | 4 | 2020 |
Methods and compositions for treating Siglec-8 associated diseases CR Bebbington, N Tomasevic, R Falahati US Patent 10,183,996, 2019 | 4 | 2019 |
AK002, a novel humanized monoclonal antibody to siglec-8, inhibits mast cell activity and depletes eosinophils in ex vivo bone marrow tissue from patients with systemic … BA Youngblood, EC Brock, J Leung, AT Chang, C Bebbington, ... Blood 132 (Supplement 1), 1104-1104, 2018 | 4 | 2018 |