| Tracing the origin and evolution of pseudokinases across the tree of life A Kwon, S Scott, R Taujale, W Yeung, KJ Kochut, PA Eyers, N Kannan Sci. Signal. 12 (578), eaav3810, 2019 | 86 | 2019 |
| mTORC2 controls the activity of PKC and Akt by phosphorylating a conserved TOR interaction motif TR Baffi, G Lordén, JM Wozniak, A Feichtner, W Yeung, AP Kornev, ... Science signaling 14 (678), eabe4509, 2021 | 77 | 2021 |
| Covalent inhibitors of EGFR family protein kinases induce degradation of human Tribbles 2 (TRIB2) pseudokinase in cancer cells DM Foulkes, DP Byrne, W Yeung, S Shrestha, FP Bailey, S Ferries, ... Sci. Signal. 11 (549), eaat7951, 2018 | 75 | 2018 |
| In vitro selection of diversely functionalized aptamers D Kong, W Yeung, R Hili Journal of the American Chemical Society 139 (40), 13977-13980, 2017 | 72 | 2017 |
| Deep evolutionary analysis reveals the design principles of fold A glycosyltransferases R Taujale, A Venkat, LC Huang, Z Zhou, W Yeung, K Rasheed, S Li, ... Elife, 2020 | 69 | 2020 |
| Conformational interconversion of MLKL and disengagement from RIPK3 precede cell death by necroptosis SE Garnish, Y Meng, A Koide, JJ Sandow, E Denbaum, AV Jacobsen, ... Nature communications 12 (1), 2211, 2021 | 62 | 2021 |
| Distinct pseudokinase domain conformations underlie divergent activation mechanisms among vertebrate MLKL orthologues KA Davies, C Fitzgibbon, SN Young, SE Garnish, W Yeung, D Coursier, ... Nature communications 11 (1), 3060, 2020 | 49 | 2020 |
| Mapping the glycosyltransferase fold landscape using interpretable deep learning R Taujale, Z Zhou, W Yeung, KW Moremen, S Li, N Kannan Nature communications 12 (1), 5656, 2021 | 28 | 2021 |
| Enzymatic Synthesis of Sequence‐Defined Synthetic Nucleic Acid Polymers with Diverse Functional Groups D Kong, Y Lei, W Yeung, R Hili Angewandte Chemie International Edition 55 (42), 13164-13168, 2016 | 28 | 2016 |
| The crystal structure of the protein kinase HIPK2 reveals a unique architecture of its CMGC-insert region C Agnew, L Liu, S Liu, W Xu, L You, W Yeung, N Kannan, D Jablons, ... Journal of Biological Chemistry 294 (37), 13545-13559, 2019 | 27 | 2019 |
| Emerging roles of the αC‐β4 loop in protein kinase structure, function, evolution, and disease W Yeung, Z Ruan, N Kannan IUBMB life 72 (6), 1189-1202, 2020 | 22 | 2020 |
| Lipid-targeting pleckstrin homology domain turns its autoinhibitory face toward the TEC kinases N Amatya, TE Wales, A Kwon, W Yeung, RE Joseph, DB Fulton, ... Proceedings of the National Academy of Sciences 116 (43), 21539-21544, 2019 | 18 | 2019 |
| Evolution of functional diversity in the holozoan tyrosine kinome W Yeung, A Kwon, R Taujale, C Bunn, A Venkat, N Kannan Molecular biology and evolution, 2021 | 13 | 2021 |
| Generation of synthetic copolymer libraries by combinatorial assembly on nucleic acid templates D Kong, W Yeung, R Hili ACS combinatorial science 18 (7), 355-370, 2016 | 13 | 2016 |
| KinOrtho: a method for mapping human kinase orthologs across the tree of life and illuminating understudied kinases LC Huang, R Taujale, N Gravel, A Venkat, W Yeung, DP Byrne, PA Eyers, ... BMC bioinformatics 22, 1-25, 2021 | 12 | 2021 |
| Quantitative Structure–Mutation–Activity Relationship Tests (QSMART) model for protein kinase inhibitor response prediction LC Huang, W Yeung, Y Wang, H Cheng, A Venkat, S Li, P Ma, K Rasheed, ... BMC bioinformatics 21, 1-22, 2020 | 12 | 2020 |
| Alignment-free estimation of sequence conservation for identifying functional sites using protein sequence embeddings W Yeung, Z Zhou, S Li, N Kannan Briefings in Bioinformatics 24 (1), bbac599, 2023 | 10 | 2023 |
| Phosformer: an explainable transformer model for protein kinase-specific phosphorylation predictions Z Zhou, W Yeung, N Gravel, M Salcedo, S Soleymani, S Li, N Kannan Bioinformatics 39 (2), btad046, 2023 | 9 | 2023 |
| A comprehensive in vivo screen of yeast farnesyltransferase activity reveals broad reactivity across a majority of CXXX sequences JH Kim, ER Hildebrandt, A Sarkar, W Yeung, LRA Waldon, N Kannan, ... G3: Genes, Genomes, Genetics 13 (7), jkad094, 2023 | 8 | 2023 |
| Evolutionary Outcomes of Diversely Functionalized Aptamers Isolated from in Vitro Evolution D Kong, M Movahedi, Y Mahdavi-Amiri, W Yeung, T Tiburcio, D Chen, ... ACS Synthetic Biology 9 (1), 43-52, 2019 | 7 | 2019 |
Natarajan KannanProfessor of Biochemistry and Bioinformatics, University of Georgia在 uga.edu 的电子邮件经过验证
