The role of cellular reactive oxygen species in cancer chemotherapy H Yang, RM Villani, H Wang, MJ Simpson, MS Roberts, M Tang, X Liang Journal of experimental & clinical cancer research 37, 1-10, 2018 | 748 | 2018 |
Patched1 inhibits epidermal progenitor cell expansion and basal cell carcinoma formation by limiting Igfbp2 activity RM Villani, C Adolphe, J Palmer, MJ Waters, BJ Wainwright Cancer Prevention Research 3 (10), 1222-1234, 2010 | 60 | 2010 |
The Hedgehog receptor Patched1 regulates myeloid and lymphoid progenitors by distinct cell-extrinsic mechanisms SL Siggins, NYN Nguyen, MP McCormack, S Vasudevan, R Villani, ... Blood, The Journal of the American Society of Hematology 114 (5), 995-1004, 2009 | 49 | 2009 |
Patched 1 and patched 2 redundancy has a key role in regulating epidermal differentiation C Adolphe, E Nieuwenhuis, R Villani, ZJ Li, P Kaur, C Hui, BJ Wainwright Journal of Investigative Dermatology 134 (7), 1981-1990, 2014 | 47 | 2014 |
Temporal regulation of natural killer T cell interferon gamma responses by β-catenin-dependent and-independent Wnt signaling JC Kling, MA Jordan, LA Pitt, J Meiners, T Thanh-Tran, LS Tran, ... Frontiers in immunology 9, 483, 2018 | 25 | 2018 |
Transgenic flash mice for in vivo quantitative monitoring of canonical Wnt signaling to track hair follicle cycle dynamics SS Hodgson, Z Neufeld, RM Villani, E Roy, K Khosrotehrani Journal of Investigative Dermatology 134 (6), 1519-1526, 2014 | 20 | 2014 |
Dominant-negative Sox18 function inhibits dermal papilla maturation and differentiation in all murine hair types R Villani, S Hodgson, J Legrand, J Greaney, HY Wong, ... Development 144 (10), 1887-1895, 2017 | 19 | 2017 |
Subtype-specific analyses reveal infiltrative basal cell carcinomas are highly interactive with their environment R Villani, V Murigneux, J Alexis, SL Sim, M Wagels, N Saunders, ... Journal of Investigative Dermatology 141 (10), 2380-2390, 2021 | 14 | 2021 |
Regional variation in epidermal susceptibility to UV-induced carcinogenesis reflects proliferative activity of epidermal progenitors E Roy, HY Wong, R Villani, T Rouille, B Salik, SL Sim, V Murigneux, ... Cell Reports 31 (9), 2020 | 12 | 2020 |
Keratinocyte Sonic Hedgehog Upregulation Drives the Development of Giant Congenital Nevi via Paracrine Endothelin-1áSecretion A Chitsazan, B Ferguson, R Villani, HY Handoko, P Mukhopadhyay, ... Journal of Investigative Dermatology 138 (4), 893-902, 2018 | 11 | 2018 |
Ectopic expression of SOX18 in Basal cell carcinoma negatively regulates tumour progression R Villani, SL Sim, E Roy, B Wainwright, M Francois, K Khosrotehrani Journal of Dermatological Science 98 (3), 179-185, 2020 | 6 | 2020 |
Differential effects of ultraviolet irradiation in neonatal versus adult mice are not explained by defective macrophage or neutrophil infiltration MP Rodero, HY Handoko, RM Villani, GJ Walker, K Khosrotehrani Journal of Investigative Dermatology 134 (7), 1991-1997, 2014 | 5 | 2014 |
Murine basal cell carcinoma leads to tumor-mediated alterations in endocrine Igf1 signaling RM Villani, MJ Waters, BJ Wainwright Endocrine-Related Cancer 20 (3), 273-281, 2013 | 4 | 2013 |
Murine dorsal hair type is genetically determined by polymorphisms in candidate genes that influence BMP and WNT signalling RM Villani, A Johnson, JA Galbraith, B Baz, HY Handoko, GJ Walker, ... Experimental Dermatology 29 (5), 450-461, 2020 | 3 | 2020 |
219 STAT5 activation in the dermal papilla is important for hair follicle growth phase induction, hair follicle regeneration and wound healing J Legrand, R Villani, E Roy, K Khosrotehrani Journal of Investigative Dermatology 136 (9), S198, 2016 | 2 | 2016 |
Integration of functional data to classify BRCA1/2 missense variants: An ENIGMA project P Lyra, L Dalcolmo, M Parsons, T Nepomuceno, S Brito, NPN Nguyen, ... Cancer Research 84 (6_Supplement), 7325-7325, 2024 | 1 | 2024 |
Analysis of bulge stem cells from the epidermis using flow cytometry RM Villani, MD Akyuz, MT Niessen, CM Niessen Skin Stem Cells: Methods and Protocols, 33-43, 2013 | 1 | 2013 |
Regional-specific calibration enables application of computational evidence for clinical classification of 5′ cis-regulatory variants in Mendelian disease RM Villani, ME McKenzie, AL Davidson, AB Spurdle The American Journal of Human Genetics, 2024 | | 2024 |
Regional-specific calibration enables application of bioinformatic evidence for clinical classification of 5 prime cis-regulatory variants in Mendelian disease RM Villani, ME McKenzie, AL Davidson, AB Spurdle | | 2023 |
Regional-specific calibration enables application of bioinformatic evidence for clinical classification of 5’cis-regulatory variants in Mendelian disease RM Villani, ME McKenzie, AL Davidson, AB Spurdle medRxiv, 2023.12. 21.23300413, 2023 | | 2023 |