关注
Anthony M. Pedley, Ph.D.
Anthony M. Pedley, Ph.D.
Assistant Professor | Carver College of Medicine, University of Iowa
在 uiowa.edu 的电子邮件经过验证 - 首页
标题
引用次数
引用次数
年份
A new view into the regulation of purine metabolism: the purinosome
AM Pedley, SJ Benkovic
Trends in biochemical sciences 42 (2), 141-154, 2017
5302017
Spatial colocalization and functional link of purinosomes with mitochondria
JB French, SA Jones, H Deng, AM Pedley, D Kim, CY Chan, H Hu, ...
Science 351 (6274), 733-737, 2016
2162016
Quantitative Analysis of Purine Nucleotides Indicates That Purinosomes Increase de Novo Purine Biosynthesis*♦
H Zhao, CR Chiaro, L Zhang, PB Smith, CY Chan, AM Pedley, RJ Pugh, ...
Journal of Biological Chemistry 290 (11), 6705-6713, 2015
1312015
Purinosome formation as a function of the cell cycle
CY Chan, H Zhao, RJ Pugh, AM Pedley, J French, SA Jones, X Zhuang, ...
Proceedings of the National Academy of Sciences 112 (5), 1368-1373, 2015
1162015
Human de novo purine biosynthesis
V Pareek, AM Pedley, SJ Benkovic
Critical reviews in biochemistry and molecular biology 56 (1), 1-16, 2021
992021
Microtubule-directed transport of purine metabolons drives their cytosolic transit to mitochondria
CY Chan, AM Pedley, D Kim, C Xia, X Zhuang, SJ Benkovic
Proceedings of the National Academy of Sciences 115 (51), 13009-13014, 2018
692018
Hypoxia drives the assembly of the multienzyme purinosome complex
C Doigneaux, AM Pedley, IN Mistry, M Papayova, SJ Benkovic, ...
Journal of Biological Chemistry 295 (28), 9551-9566, 2020
412020
The purinosome: a case study for a mammalian metabolon
AM Pedley, V Pareek, SJ Benkovic
Annual review of biochemistry 91 (1), 89-106, 2022
372022
Replication protein A dynamically regulates monoubiquitination of proliferating cell nuclear antigen
M Hedglin, M Aitha, A Pedley, SJ Benkovic
Journal of biological chemistry 294 (13), 5157-5168, 2019
312019
Purine biosynthetic enzymes assemble into liquid-like condensates dependent on the activity of chaperone protein HSP90
AM Pedley, JP Boylan, CY Chan, EL Kennedy, M Kyoung, SJ Benkovic
Journal of Biological Chemistry 298 (5), 2022
262022
Role of HSP90 in the Regulation of de Novo Purine Biosynthesis
AM Pedley, GI Karras, X Zhang, S Lindquist, SJ Benkovic
Biochemistry 57 (23), 3217-3221, 2018
232018
Flexibility of PCNA-protein interface accommodates differential binding partners
AM Pedley, MA Lill, VJ Davisson
PLoS One 9 (7), e102481, 2014
232014
Mapping post-translational modifications of de novo purine biosynthetic enzymes: implications for pathway regulation
C Liu, GM Knudsen, AM Pedley, J He, JL Johnson, TM Yaron, LC Cantley, ...
Journal of proteome research 18 (5), 2078-2087, 2019
182019
Conformational changes involving ammonia tunnel formation and allosteric control in GMP synthetase
JC Oliver, R Gudihal, JW Burgner, AM Pedley, AT Zwierko, VJ Davisson, ...
Archives of biochemistry and biophysics 545, 22-32, 2014
162014
Selective inhibition of STAT3 phosphorylation using a nuclear-targeted kinase inhibitor
MD Bartolowits, W Brown, R Ali, AM Pedley, Q Chen, KE Harvey, ...
ACS chemical biology 12 (9), 2371-2378, 2017
142017
The roles of molecular chaperones in regulating cell metabolism
MJ Binder, AM Pedley
FEBS letters 597 (13), 1681-1701, 2023
112023
Detecting purinosome metabolon formation with fluorescence microscopy
AM Pedley, SJ Benkovic
Protein Complex Assembly: Methods and Protocols, 279-289, 2018
92018
Identification of FAK substrate peptides via colorimetric screening of a one‐bead one‐peptide combinatorial library
LA Witucki, LS Borowicz, AM Pedley, J Curtis‐Fisk, EG Kuszpit
Journal of Peptide Science 21 (4), 302-311, 2015
32015
Evaluation of Proliferating Cell Nuclear Antigen as a Therapeutic Target in DNA Repair
AM Pedley
2013
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