Manganese deposition in basal ganglia structures results from both portal-systemic shunting and liver dysfunction C Rose, RF Butterworth, J Zayed, L Normandin, K Todd, A Michalak, ... Gastroenterology 117 (3), 640-644, 1999 | 344 | 1999 |
Hepatic encephalopathy: Novel insights into classification, pathophysiology and therapy CF Rose, P Amodio, JS Bajaj, RK Dhiman, S Montagnese, ... Journal of hepatology 73 (6), 1526-1547, 2020 | 322 | 2020 |
Identifying the direct effects of ammonia on the brain CR Bosoi, CF Rose Metabolic brain disease 24, 95-102, 2009 | 274 | 2009 |
Ammonia toxicity: from head to toe? S Dasarathy, RP Mookerjee, V Rackayova, V Rangroo Thrane, ... Metabolic brain disease 32, 529-538, 2017 | 237 | 2017 |
Astrocyte glutamine synthetase: pivotal in health and disease CF Rose, A Verkhratsky, V Parpura Biochemical Society Transactions 41 (6), 1518-1524, 2013 | 223 | 2013 |
Decreased glutamate transporter (GLT-1) expression in frontal cortex of rats with acute liver failure K Knecht, A Michalak, C Rose, JD Rothstein, RF Butterworth Neuroscience letters 229 (3), 201-203, 1997 | 209 | 1997 |
Neuroactive amino acids and glutamate (NMDA) receptors in frontal cortex of rats with experimental acute liver failure A Michalak, C Rose, J Butterworth, RF Butterworth Hepatology 24 (4), 908-913, 1996 | 205 | 1996 |
Myosteatosis and sarcopenia are associated with hepatic encephalopathy in patients with cirrhosis RA Bhanji, C Moctezuma-Velazquez, A Duarte-Rojo, M Ebadi, S Ghosh, ... Hepatology international 12, 377-386, 2018 | 202 | 2018 |
L‐Ornithine‐L‐aspartate lowers plasma and cerebrospinal fluid ammonia and prevents brain edema in rats with acute liver failure C Rose, A Michalak, KV Rao, G Quack, G Kircheis, RF Butterworth Hepatology 30 (3), 636-640, 1999 | 194 | 1999 |
Ammonia‐lowering strategies for the treatment of hepatic encephalopathy CF Rose Clinical Pharmacology & Therapeutics 92 (3), 321-331, 2012 | 162 | 2012 |
Mild hypothermia delays the onset of coma and prevents brain edema and extracellular brain glutamate accumulation in rats with acute liver failure C Rose, A Michalak, M Pannunzio, N Chatauret, A Rambaldi, ... Hepatology 31 (4), 872-877, 2000 | 156 | 2000 |
Acute insult of ammonia leads to calcium-dependent glutamate release from cultured astrocytes, an effect of pH C Rose, W Kresse, H Kettenmann Journal of biological chemistry 280 (22), 20937-20944, 2005 | 144 | 2005 |
Effects of hypothermia on brain glucose metabolism in acute liver failure: a 1H/13C-nuclear magnetic resonance study N Chatauret, C Zwingmann, C Rose, D Leibfritz, RF Butterworth Gastroenterology 125 (3), 815-824, 2003 | 123 | 2003 |
L-ornithine-L-aspartate in experimental portal-systemic encephalopathy: therapeutic efficacy and mechanism of action C Rose, A Michalak, P Pannunzio, G Therrien, G Quack, G Kircheis, ... Metabolic brain disease 13, 147-157, 1998 | 119 | 1998 |
Oxidative stress: a systemic factor implicated in the pathogenesis of hepatic encephalopathy CR Bosoi, CF Rose Metabolic brain disease 28, 175-178, 2013 | 114 | 2013 |
Role of manganese in the pathogenesis of portal-systemic encephalopathy GP Layrargues, C Rose, L Spahr, J Zayed, L Normandin, RF Butterworth Metabolic brain disease 13, 311-317, 1998 | 110 | 1998 |
L‐ornithine phenylacetate attenuates increased arterial and extracellular brain ammonia and prevents intracranial hypertension in pigs with acute liver failure LM Ytrebø, RG Kristiansen, H Mæhre, OM Fuskevåg, T Kalstad, ... Hepatology 50 (1), 165-174, 2009 | 108 | 2009 |
Systemic oxidative stress is implicated in the pathogenesis of brain edema in rats with chronic liver failure. CR Bosoi, X Yang, J Huynh, C Parent-Robitaille, W Jiang, M Tremblay, ... Free radical biology & medicine 52 (7), 1228-1235, 2012 | 106 | 2012 |
Effect of portacaval anastomosis on glutamine synthetase protein and gene expression in brain, liver and skeletal muscle P Desjardins, KVR Rao, A Michalak, C Rose, RF Butterworth Metabolic brain disease 14, 273-280, 1999 | 106 | 1999 |
Induction of astrocytic cyclooxygenase-2 in epileptic patients with hippocampal sclerosis P Desjardins, A Sauvageau, A Bouthillier, D Navarro, AS Hazell, C Rose, ... Neurochemistry international 42 (4), 299-303, 2003 | 105 | 2003 |