| BRAF-V600E expression in precursor versus differentiated dendritic cells defines clinically distinct LCH risk groups ML Berres, KPH Lim, T Peters, J Price, H Takizawa, H Salmon, J Idoyaga, ... The Journal of experimental medicine 211 (4), 669, 2014 | 443 | 2014 |
| Mutually exclusive recurrent somatic mutations in MAP2K1 and BRAF support a central role for ERK activation in LCH pathogenesis R Chakraborty, OA Hampton, X Shen, SJ Simko, A Shih, H Abhyankar, ... Blood, The Journal of the American Society of Hematology 124 (19), 3007-3015, 2014 | 441 | 2014 |
| Alternative genetic mechanisms of BRAF activation in Langerhans cell histiocytosis R Chakraborty, TM Burke, OA Hampton, DJ Zinn, KPH Lim, H Abhyankar, ... Blood, The Journal of the American Society of Hematology 128 (21), 2533-2537, 2016 | 152 | 2016 |
| Differentiating skin-limited and multisystem Langerhans cell histiocytosis SJ Simko, B Garmezy, H Abhyankar, PJ Lupo, R Chakraborty, KPH Lim, ... The Journal of pediatrics 165 (5), 990-996, 2014 | 121 | 2014 |
| Redox regulation of interleukin-4 signaling P Sharma, R Chakraborty, L Wang, B Min, ML Tremblay, T Kawahara, ... Immunity 29 (4), 551-564, 2008 | 114 | 2008 |
| CNS Langerhans cell histiocytosis: common hematopoietic origin for LCH‐associated neurodegeneration and mass lesions KL McClain, J Picarsic, R Chakraborty, D Zinn, H Lin, H Abhyankar, ... Cancer 124 (12), 2607-2620, 2018 | 107 | 2018 |
| Langerhans Cell Histiocytosis: Emerging Insights and Clinical Implications. DJ Zinn, R Chakraborty, CE Allen Oncology (Williston Park, NY) 30 (2), 122-32, 139, 2016 | 96 | 2016 |
| Activation of Wnt signaling arrests effector differentiation in human peripheral and cord blood-derived T lymphocytes S Muralidharan, PJ Hanley, E Liu, R Chakraborty, C Bollard, E Shpall, ... The Journal of Immunology 187 (10), 5221-5232, 2011 | 74 | 2011 |
| RAF/MEK/extracellular signal–related kinase pathway suppresses dendritic cell migration and traps dendritic cells in Langerhans cell histiocytosis lesions B Hogstad, ML Berres, R Chakraborty, J Tang, C Bigenwald, ... The Journal of experimental medicine 215 (1), 319, 2018 | 73 | 2018 |
| BRAFV600E-induced senescence drives Langerhans cell histiocytosis pathophysiology C Bigenwald, J Le Berichel, CM Wilk, R Chakraborty, ST Chen, ... Nature medicine 27 (5), 851-861, 2021 | 53 | 2021 |
| BRAF-V600E expression in precursor versus differentiated dendritic cells defines clinically distinct LCH risk groups ML Berres, KPH Lim, T Peters, J Price, H Takizawa, H Salmon, J Idoyaga, ... Journal of Experimental Medicine 212 (2), 281-281, 2015 | 51 | 2015 |
| New somatic BRAF splicing mutation in Langerhans cell histiocytosis S Héritier, Z Hélias-Rodzewicz, R Chakraborty, AG Sengal, ... Molecular Cancer 16, 1-5, 2017 | 48 | 2017 |
| Robust and cost effective expansion of human regulatory T cells highly functional in a xenograft model of graft-versus-host disease R Chakraborty, A Mahendravada, SK Perna, CM Rooney, HE Heslop, ... haematologica 98 (4), 533, 2013 | 39 | 2013 |
| Activating MAPK1 (ERK2) mutation in an aggressive case of disseminated juvenile xanthogranuloma R Chakraborty, OA Hampton, H Abhyankar, DJ Zinn, A Grimes, B Skull, ... Oncotarget 8 (28), 46065, 2017 | 32 | 2017 |
| IFN-γ signature in the plasma proteome distinguishes pediatric hemophagocytic lymphohistiocytosis from sepsis and SIRS H Lin, BP Scull, BR Goldberg, HA Abhyankar, OE Eckstein, DJ Zinn, ... Blood advances 5 (17), 3457-3467, 2021 | 31 | 2021 |
| Overcoming T-cell exhaustion in LCH: PD-1 blockade and targeted MAPK inhibition are synergistic in a mouse model of LCH A Sengal, J Velazquez, M Hahne, TM Burke, H Abhyankar, R Reyes, ... Blood, The Journal of the American Society of Hematology 137 (13), 1777-1791, 2021 | 31 | 2021 |
| Circulating CD1c+ myeloid dendritic cells are potential precursors to LCH lesion CD1a+ CD207+ cells KPH Lim, P Milne, M Poidinger, K Duan, H Lin, N McGovern, H Abhyankar, ... Blood advances 4 (1), 87-99, 2020 | 30 | 2020 |
| p53 nongenotoxic activation and mTORC1 inhibition lead to effective combination for neuroblastoma therapy M Moreno-Smith, A Lakoma, Z Chen, L Tao, KA Scorsone, L Schild, ... Clinical Cancer Research 23 (21), 6629-6639, 2017 | 27 | 2017 |
| A genome-wide association study of LCH identifies a variant in SMAD6 associated with susceptibility EC Peckham-Gregory, R Chakraborty, ME Scheurer, JW Belmont, ... Blood, The Journal of the American Society of Hematology 130 (20), 2229-2232, 2017 | 20 | 2017 |
| Changes in chemokine receptor expression of regulatory T cells after ex vivo culture R Chakraborty, C Rooney, G Dotti, B Savoldo Journal of Immunotherapy 35 (4), 329-336, 2012 | 20 | 2012 |
