The OncoPPi network of cancer-focused protein–protein interactions to inform biological insights and therapeutic strategies Z Li, AA Ivanov, R Su, V Gonzalez-Pecchi, Q Qi, S Liu, P Webber, ... Nature communications 8 (1), 14356, 2017 | 278 | 2017 |
An expanded universe of cancer targets WC Hahn, JS Bader, TP Braun, A Califano, PA Clemons, BJ Druker, ... Cell 184 (5), 1142-1155, 2021 | 160 | 2021 |
Dual gene activation and knockout screen reveals directional dependencies in genetic networks M Boettcher, R Tian, JA Blau, E Markegard, RT Wagner, D Wu, X Mo, ... Nature biotechnology 36 (2), 170-178, 2018 | 146 | 2018 |
Development of a miniaturized 3D organoid culture platform for ultra-high-throughput screening Y Du, X Li, Q Niu, X Mo, M Qui, T Ma, CJ Kuo, H Fu Journal of Molecular Cell Biology 12 (8), 630-643, 2020 | 83 | 2020 |
Activation of MAPK by inverse agonists in six naturally occurring constitutively active mutant human melanocortin-4 receptors XL Mo, YX Tao Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1832 (12 …, 2013 | 62 | 2013 |
Functions of transmembrane domain 3 of human melanocortin-4 receptor XL Mo, R Yang, YX Tao Journal of Molecular Endocrinology 49 (3), 221-235, 2012 | 54 | 2012 |
Association of block copolymer in nonselective solvent F Ke, X Mo, R Yang, Y Wang, D Liang Macromolecules 42 (14), 5339-5344, 2009 | 54 | 2009 |
The OncoPPi Portal: an integrative resource to explore and prioritize protein–protein interactions for cancer target discovery AA Ivanov, B Revennaugh, L Rusnak, V Gonzalez-Pecchi, X Mo, ... Bioinformatics 34 (7), 1183-1191, 2018 | 51 | 2018 |
In vivo screening identifies GATAD2B as a metastasis driver in KRAS-driven lung cancer CL Grzeskowiak, ST Kundu, X Mo, AA Ivanov, O Zagorodna, H Lu, ... Nature communications 9 (1), 2732, 2018 | 41 | 2018 |
HTiP: high-throughput immunomodulator phenotypic screening platform to reveal IAP antagonists as anti-cancer immune enhancers X Mo, C Tang, Q Niu, T Ma, Y Du, H Fu Cell chemical biology 26 (3), 331-339. e3, 2019 | 39 | 2019 |
Enabling systematic interrogation of protein–protein interactions in live cells with a versatile ultra-high-throughput biosensor platform XL Mo, Y Luo, AA Ivanov, R Su, JJ Havel, Z Li, FR Khuri, Y Du, H Fu Journal of molecular cell biology 8 (3), 271-281, 2016 | 38 | 2016 |
BRET: NanoLuc-based bioluminescence resonance energy transfer platform to monitor protein-protein interactions in live cells XL Mo, H Fu High throughput screening: methods and protocols, 263-271, 2016 | 37 | 2016 |
Free fatty acid receptor GPR120 and pathogenesis of obesity and type 2 diabetes mellitus XL Mo, HK Wei, J Peng, YX Tao Progress in molecular biology and translational science 114, 251-276, 2013 | 34 | 2013 |
AKT1, LKB1, and YAP1 revealed as MYC interactors with NanoLuc-based protein-fragment complementation assay X Mo, Q Qi, AA Ivanov, Q Niu, Y Luo, J Havel, R Goetze, S Bell, ... Molecular pharmacology 91 (4), 339-347, 2017 | 32 | 2017 |
OncoPPi-informed discovery of mitogen-activated protein kinase kinase 3 as a novel binding partner of c-Myc AA Ivanov, V Gonzalez-Pecchi, LF Khuri, Q Niu, Y Wang, Y Xu, Y Bai, ... Oncogene 36 (42), 5852-5860, 2017 | 30 | 2017 |
Systematic discovery of mutation-directed neo-protein-protein interactions in cancer X Mo, Q Niu, AA Ivanov, YH Tsang, C Tang, C Shu, Q Li, K Qian, ... Cell 185 (11), 1974-1985. e12, 2022 | 24 | 2022 |
Targeting GPR119 for the potential treatment of type 2 diabetes mellitus XL Mo, Z Yang, YX Tao Progress in molecular biology and translational science 121, 95-131, 2014 | 24 | 2014 |
Effect of Overlap Concentration and Persistence Length on DNA Separation in Polymer Solutions by Electrophoresis F Ke, X Mo, D Liang Chinese Journal of Polymer Science 27 (05), 601-610, 2009 | 20 | 2009 |
Hypomorph mutation-directed small-molecule protein-protein interaction inducers to restore mutant SMAD4-suppressed TGF-β signaling C Tang, X Mo, Q Niu, A Wahafu, X Yang, M Qui, AA Ivanov, Y Du, H Fu Cell chemical biology 28 (5), 636-647. e5, 2021 | 18 | 2021 |
Development of a time-resolved fluorescence resonance energy transfer ultrahigh-throughput screening assay for targeting the NSD3 and MYC interaction J Xiong, VG Pecchi, M Qui, AA Ivanov, X Mo, Q Niu, X Chen, H Fu, Y Du Assay and drug development technologies 16 (2), 96-106, 2018 | 16 | 2018 |