Expression of hepatic drug-metabolizing cytochrome p450 enzymes and their intercorrelations: a meta-analysis B Achour, J Barber, A Rostami-Hodjegan Drug Metabolism and Disposition 42 (8), 1349-1356, 2014 | 242 | 2014 |
Simultaneous quantification of the abundance of several cytochrome P450 and uridine 5'-diphospho-glucuronosyltransferase enzymes in human liver microsomes using multiplexed … B Achour, MR Russell, J Barber, A Rostami-Hodjegan Drug Metabolism and Disposition 42 (4), 500-510, 2014 | 185 | 2014 |
Variability in mass spectrometry-based quantification of clinically relevant drug transporters and drug metabolizing enzymes C Wegler, FZ Gaugaz, TB Andersson, JR Wiśniewski, D Busch, C Gröer, ... Molecular Pharmaceutics 14 (9), 3142-3151, 2017 | 111 | 2017 |
Model-Informed Precision Dosing: Background, Requirements, Validation, Implementation, and Forward Trajectory of Individualizing Drug Therapy AS Darwich, TM Polasek, JK Aronson, K Ogungbenro, DFB Wright, ... Annual Review of Pharmacology and Toxicology 61 (1), 225-245, 2021 | 104 | 2021 |
Proteomic quantification of human blood–brain barrier SLC and ABC transporters in healthy individuals and dementia patients ZM Al-Majdoub, H Al Feteisi, B Achour, S Warwood, S Neuhoff, ... Molecular Pharmaceutics 16 (3), 1220-1233, 2019 | 101 | 2019 |
Meta-analysis of expression of hepatic organic anion–transporting polypeptide (OATP) transporters in cellular systems relative to human liver tissue J Badée, B Achour, A Rostami-Hodjegan, A Galetin Drug Metabolism and Disposition 43 (4), 424-432, 2015 | 100 | 2015 |
Toward a Consensus on Applying Quantitative Liquid Chromatography‐Tandem Mass Spectrometry Proteomics in Translational Pharmacology Research: A White Paper B Prasad, B Achour, P Artursson, CECA Hop, Y Lai, PC Smith, J Barber, ... Clinical Pharmacology & Therapeutics 106 (3), 525-543, 2019 | 96 | 2019 |
Cytochrome P450 pig liver pie: determination of individual cytochrome P450 isoform contents in microsomes from two pig livers using liquid chromatography in conjunction with … B Achour, J Barber, A Rostami-Hodjegan Drug Metabolism and Disposition 39 (11), 2130-2134, 2011 | 95 | 2011 |
Quantitative proteomics of clinically relevant drug-metabolizing enzymes and drug transporters and their intercorrelations in the human small intestine N Couto, ZM Al-Majdoub, S Gibson, PJ Davies, B Achour, MD Harwood, ... Drug Metabolism and Disposition 48 (4), 245-254, 2020 | 87 | 2020 |
Identification and quantification of blood–brain barrier transporters in isolated rat brain microvessels H Al Feteisi, ZM Al‐Majdoub, B Achour, N Couto, A Rostami‐Hodjegan, ... Journal of Neurochemistry 146 (6), 670-685, 2018 | 75 | 2018 |
Quantification of proteins involved in drug metabolism and disposition in the human liver using label-free global proteomics N Couto, ZM Al-Majdoub, B Achour, PC Wright, A Rostami-Hodjegan, ... Molecular Pharmaceutics 16 (2), 632-647, 2019 | 71 | 2019 |
Liquid Biopsy Enables Quantification of the Abundance and Interindividual Variability of Hepatic Enzymes and Transporters B Achour, ZM Al‐Majdoub, A Grybos‐Gajniak, K Lea, P Kilford, M Zhang, ... Clinical Pharmacology & Therapeutics 109 (1), 222-232, 2021 | 67 | 2021 |
Application of an LC–MS/MS method for the simultaneous quantification of human intestinal transporter proteins absolute abundance using a QconCAT technique MD Harwood, B Achour, MR Russell, GL Carlson, G Warhurst, ... Journal of Pharmaceutical and Biomedical Analysis 110, 27-33, 2015 | 65 | 2015 |
Alternative fusion protein strategies to express recalcitrant QconCAT proteins for quantitative proteomics of human drug metabolizing enzymes and transporters MR Russell, B Achour, EA Mckenzie, R Lopez, MD Harwood, ... Journal of Proteome Research 12 (12), 5934-5942, 2013 | 64 | 2013 |
In vitro–in vivo extrapolation scaling factors for intestinal P-glycoprotein and breast cancer resistance protein: part I: a cross-laboratory comparison of transporter-protein … MD Harwood, B Achour, S Neuhoff, MR Russell, G Carlson, G Warhurst, ... Drug Metabolism and Disposition 44 (3), 297-307, 2016 | 55 | 2016 |
Protein expression of various hepatic uridine 5′‐diphosphate glucuronosyltransferase (UGT) enzymes and their inter‐correlations: a meta‐analysis B Achour, A Rostami‐Hodjegan, J Barber Biopharmaceutics and Drug Disposition 35 (6), 353-361, 2014 | 55 | 2014 |
Quantitative characterization of major hepatic UDP-glucuronosyltransferase enzymes in human liver microsomes: comparison of two proteomic methods and correlation with catalytic … B Achour, A Dantonio, M Niosi, JJ Novak, JK Fallon, J Barber, PC Smith, ... Drug Metabolism and Disposition 45 (10), 1102-1112, 2017 | 53 | 2017 |
Choice of LC-MS methods for the absolute quantification of drug-metabolizing enzymes and transporters in human tissue: a comparative cost analysis H Al Feteisi, B Achour, J Barber, A Rostami-Hodjegan The AAPS Journal 17 (2), 438-446, 2015 | 48 | 2015 |
Global Proteomic Analysis of Human Liver Microsomes: Rapid Characterization and Quantification of Hepatic Drug-Metabolizing Enzymes B Achour, H Al-Feteisi, F Lanucara, A Rostami-Hodjegan, J Barber Drug Metabolism and Disposition 45 (6), 666-675, 2017 | 46 | 2017 |
Non-uniformity of changes in drug-metabolizing enzymes and transporters in liver cirrhosis: implications for drug dosage adjustment E El-Khateeb, B Achour, ZM Al-Majdoub, J Barber, A Rostami-Hodjegan Molecular pharmaceutics 18 (9), 3563-3577, 2021 | 40 | 2021 |