| Neuroinflammation in Alzheimer's disease MT Heneka, MJ Carson, J El Khoury, GE Landreth, F Brosseron, ... The Lancet Neurology 14 (4), 388-405, 2015 | 5420 | 2015 |
| Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease JC Lambert, CA Ibrahim-Verbaas, D Harold, AC Naj, R Sims, ... Nature genetics 45 (12), 1452-1458, 2013 | 4405 | 2013 |
| Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease D Harold, R Abraham, P Hollingworth, R Sims, A Gerrish, ML Hamshere, ... Nature genetics 41 (10), 1088-1093, 2009 | 3319 | 2009 |
| Genetic meta-analysis of diagnosed Alzheimer’s disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing BW Kunkle, B Grenier-Boley, R Sims, JC Bis, V Damotte, AC Naj, ... Nature genetics 51 (3), 414-430, 2019 | 2258 | 2019 |
| Common variants at ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer's disease P Hollingworth, D Harold, R Sims, A Gerrish, JC Lambert, ... Nature genetics 43 (5), 429-435, 2011 | 2191 | 2011 |
| Long-term effects of Aβ42 immunisation in Alzheimer's disease: follow-up of a randomised, placebo-controlled phase I trial C Holmes, D Boche, D Wilkinson, G Yadegarfar, V Hopkins, A Bayer, ... The Lancet 372 (9634), 216-223, 2008 | 1849 | 2008 |
| Microglia in neurodegenerative disease VH Perry, JAR Nicoll, C Holmes Nature Reviews Neurology 6 (4), 193-201, 2010 | 1821 | 2010 |
| Neuropathology of human Alzheimer disease after immunization with amyloid-β peptide: a case report JAR Nicoll, D Wilkinson, C Holmes, P Steart, H Markham, RO Weller Nature medicine 9 (4), 448-452, 2003 | 1787 | 2003 |
| Systemic inflammation and disease progression in Alzheimer disease C Holmes, C Cunningham, E Zotova, J Woolford, C Dean, S Kerr, ... Neurology 73 (10), 768-774, 2009 | 1269 | 2009 |
| Systemic infections and inflammation affect chronic neurodegeneration VH Perry, C Cunningham, C Holmes Nature Reviews Immunology 7 (2), 161-167, 2007 | 1176 | 2007 |
| Microglial priming in neurodegenerative disease VH Perry, C Holmes Nature Reviews Neurology 10 (4), 217-224, 2014 | 1119 | 2014 |
| New insights into the genetic etiology of Alzheimer’s disease and related dementias C Bellenguez, F Küçükali, IE Jansen, L Kleineidam, S Moreno-Grau, ... Nature genetics 54 (4), 412-436, 2022 | 1007 | 2022 |
| The Montreal Cognitive Assessment: validity and utility in a memory clinic setting T Smith, N Gildeh, C Holmes The Canadian Journal of Psychiatry 52 (5), 329-332, 2007 | 996 | 2007 |
| Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease R Sims, SJ Van Der Lee, AC Naj, C Bellenguez, N Badarinarayan, ... Nature genetics 49 (9), 1373-1384, 2017 | 919 | 2017 |
| Donepezil and memantine for moderate-to-severe Alzheimer's disease R Howard, R McShane, J Lindesay, C Ritchie, A Baldwin, R Barber, ... New England Journal of Medicine 366 (10), 893-903, 2012 | 918 | 2012 |
| The epidemiology of DSM-III-R bipolar I disorder in a general population survey RC Kessler, DR Rubinow, C Holmes, JM Abelson, S Zhao Bipolar Disorder, 11-21, 2019 | 798 | 2019 |
| Sensitivity and specificity of dopamine transporter imaging with 123I-FP-CIT SPECT in dementia with Lewy bodies: a phase III, multicentre study I McKeith, J O'Brien, Z Walker, K Tatsch, J Booij, J Darcourt, A Padovani, ... The Lancet Neurology 6 (4), 305-313, 2007 | 744 | 2007 |
| Sertraline or mirtazapine for depression in dementia (HTA-SADD): a randomised, multicentre, double-blind, placebo-controlled trial S Banerjee, J Hellier, M Dewey, R Romeo, C Ballard, R Baldwin, ... The Lancet 378 (9789), 403-411, 2011 | 597 | 2011 |
| Rare coding variants in the phospholipase D3 gene confer risk for Alzheimer’s disease C Cruchaga, CM Karch, SC Jin, BA Benitez, Y Cai, R Guerreiro, O Harari, ... Nature 505 (7484), 550-554, 2014 | 525 | 2014 |
| Systemic inflammation and A lzheimer's disease C Holmes Neuropathology and applied neurobiology 39 (1), 51-68, 2013 | 500 | 2013 |
