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Leland Taylor
Leland Taylor
National Human Genome Research Institute - University of Cambridge
在 nih.gov 的电子邮件经过验证 - 首页
标题
引用次数
引用次数
年份
Chromatin stretch enhancer states drive cell-specific gene regulation and harbor human disease risk variants
SCJ Parker, ML Stitzel, DL Taylor, JM Orozco, MR Erdos, JA Akiyama, ...
Proceedings of the National Academy of Sciences 110 (44), 17921-17926, 2013
711*2013
Genetic regulatory signatures underlying islet gene expression and type 2 diabetes
A Varshney, LJ Scott, RP Welch, MR Erdos, PS Chines, N Narisu, ...
Proceedings of the National Academy of Sciences 114 (9), 2301-2306, 2017
1972017
The genetic regulatory signature of type 2 diabetes in human skeletal muscle
LJ Scott, MR Erdos, JR Huyghe, RP Welch, AT Beck, BN Wolford, ...
Nature communications 7 (1), 11764, 2016
1262016
Integrative analysis of gene expression, DNA methylation, physiological traits, and genetic variation in human skeletal muscle
DL Taylor, AU Jackson, N Narisu, G Hemani, MR Erdos, PS Chines, ...
Proceedings of the National Academy of Sciences 116 (22), 10883-10888, 2019
1092019
BoostMe accurately predicts DNA methylation values in whole-genome bisulfite sequencing of multiple human tissues
LS Zou, MR Erdos, DL Taylor, PS Chines, A Varshney, ...
BMC genomics 19, 1-15, 2018
422018
Interactions between genetic variation and cellular environment in skeletal muscle gene expression
DL Taylor, DA Knowles, LJ Scott, AH Ramirez, FP Casale, BN Wolford, ...
PLoS One 13 (4), e0195788, 2018
222018
Human pancreatic islet microRNAs implicated in diabetes and related traits by large-scale genetic analysis
HJ Taylor, YH Hung, N Narisu, MR Erdos, M Kanke, T Yan, CM Grenko, ...
Proceedings of the National Academy of Sciences 120 (7), e2206797120, 2023
122023
Calcification of the abdominal aorta is an under-appreciated cardiovascular disease risk factor in the general population
A Sethi, DL Taylor, JG Ruby, J Venkataraman, E Sorokin, M Cule, ...
Frontiers in Cardiovascular Medicine 9, 1003246, 2022
12*2022
The promise and reality of therapeutic discovery from large cohorts
E Melamud, DL Taylor, A Sethi, M Cule, A Baryshnikova, D Saleheen, ...
The Journal of Clinical Investigation 130 (2), 575-581, 2020
102020
Bacterial Logic Devices Reveal Unexpected Behavior of Frameshift Suppressor tRNAs
EM Sawyer, C Barta, R Clemente, M Conn, C Davis, C Doyle, M Gearing, ...
Interdisciplinary Bio Central 4 (10), 2012
52012
Illuminating the Black Box of Genome Sequence Assembly: A Free Online Tool to Introduce Students to Bioinformatics
DL Taylor, AM Campbell, LJ Heyer
The American Biology Teacher 75 (8), 572-577, 2013
32013
Functional interrogation of twenty type 2 diabetes associated genes using isogenic hESC-derived β-like cells
D Xue, N Narisu, DL Taylor, M Zhang, C Grenko, HJ Taylor, T Yan, X Tang, ...
bioRxiv, 2023.05. 07.539774, 2023
2*2023
An integrative single-cell multi-omics profiling of human pancreatic islets identifies T1D associated genes and regulatory signals
Z Zhao, RDO Albanus, H Taylor, X Tang, Y Han, P Orchard, A Varshney, ...
Research Square, 2023
12023
Modeling islet enhancers using deep learning identifies candidate causal variants at loci associated with T2D and glycemic traits
S Hudaiberdiev, DL Taylor, W Song, N Narisu, RM Bhuiyan, HJ Taylor, ...
Proceedings of the National Academy of Sciences 120 (35), e2206612120, 2023
12023
Single-cell transcriptomic profiling of human pancreatic islets reveals genes responsive to glucose exposure over 24 hours
CM Grenko, LL Bonnycastle, HJ Taylor, T Yan, AJ Swift, CC Robertson, ...
bioRxiv, 2023
2023
Single-cell RNA sequencing reveals dysregulated cellular programmes in the inflamed epithelium of Crohn's disease patients.
M Krzak, T Alegbe, DL Taylor, MH Ghouraba, M Strickland, R Satti, ...
medRxiv, 2023.09. 06.23295056, 2023
2023
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