The fission yeast pmk1+ gene encodes a novel mitogen-activated protein kinase homolog which regulates cell integrity and functions coordinately with the protein kinase C pathway T Toda, S Dhut, G Superti-Furga, Y Gotoh, E Nishida, R Sugiura, T Kuno Molecular and cellular biology, 1996 | 254 | 1996 |
pmp1+, a suppressor of calcineurin deficiency, encodes a novel MAP kinase phosphatase in fission yeast R Sugiura, T Toda, H Shuntoh, M Yanagida, T Kuno The EMBO journal, 1998 | 139 | 1998 |
ERK: a double-edged sword in cancer. ERK-dependent apoptosis as a potential therapeutic strategy for cancer R Sugiura, R Satoh, T Takasaki Cells 10 (10), 2509, 2021 | 132 | 2021 |
The MAPK kinase Pek1 acts as a phosphorylation-dependent molecular switch R Sugiura, T Toda, S Dhut, H Shuntoh, T Kuno, T Kuno Nature 399 (6735), 479-483, 1999 | 126 | 1999 |
Phosphatidylinositol 4-phosphate 5-kinase Its3 and calcineurin Ppb1 coordinately regulate cytokinesis in fission yeast Y Zhang, R Sugiura, Y Lu, M Asami, T Maeda, T Itoh, T Takenawa, ... Journal of Biological Chemistry 275 (45), 35600-35606, 2000 | 122 | 2000 |
Zinc finger protein Prz1 regulates Ca2+ but not Cl− homeostasis in fission yeast: identification of distinct branches of calcineurin signaling pathway in fission yeast S Hirayama, R Sugiura, Y Lu, T Maeda, K Kawagishi, M Yokoyama, ... Journal of Biological Chemistry 278 (20), 18078-18084, 2003 | 102 | 2003 |
Role of the Rab GTP-binding protein Ypt3 in the fission yeast exocytic pathway and its connection to calcineurin function H Cheng, R Sugiura, W Wu, M Fujita, Y Lu, SO Sio, R Kawai, K Takegawa, ... Molecular biology of the cell 13 (8), 2963-2976, 2002 | 99 | 2002 |
Molecular genetic analysis of the calcineurin signaling pathways R Sugiura, SO Sio, H Shuntoh, T Kuno* Cellular and Molecular Life Sciences CMLS 58, 278-288, 2001 | 98 | 2001 |
Loss of Apm1, the μ1 subunit of the clathrin-associated adaptor-protein-1 complex, causes distinct phenotypes and synthetic lethality with calcineurin deletion in fission yeast A Kita, R Sugiura, H Shoji, Y He, L Deng, Y Lu, SO Sio, K Takegawa, ... Molecular biology of the cell 15 (6), 2920-2931, 2004 | 92 | 2004 |
Feedback regulation of MAPK signalling by an RNA-binding protein R Sugiura, A Kita, Y Shimizu, H Shuntoh, SO Sio, T Kuno Nature 424 (6951), 961-965, 2003 | 90 | 2003 |
Downregulation of vascular soluble guanylate cyclase induced by high salt intake in spontaneously hypertensive rats S Kagota, A Tamashiro, Y Yamaguchi, R Sugiura, T Kuno, K Nakamura, ... British journal of pharmacology 134 (4), 737-744, 2001 | 88 | 2001 |
Rho2 is a target of the farnesyltransferase Cpp1 and acts upstream of Pmk1 mitogen-activated protein kinase signaling in fission yeast Y Ma, T Kuno, A Kita, Y Asayama, R Sugiura Molecular biology of the cell 17 (12), 5028-5037, 2006 | 85 | 2006 |
Calcineurin phosphatase in signal transduction: lessons from fission yeast R Sugiura, SO Sio, H Shuntoh, T Kuno Genes to Cells 7 (7), 619-627, 2002 | 75 | 2002 |
Atf1 is a target of the mitogen-activated protein kinase Pmk1 and regulates cell integrity in fission yeast H Takada, M Nishimura, Y Asayama, Y Mannse, S Ishiwata, A Kita, A Doi, ... Molecular biology of the cell 18 (12), 4794-4802, 2007 | 67 | 2007 |
Real-Time Monitoring of Calcineurin Activity in Living Cells: Evidence for Two Distinct Ca2+-dependent Pathways in Fission Yeast L Deng, R Sugiura, M Takeuchi, M Suzuki, H Ebina, T Takami, A Koike, ... Molecular biology of the cell 17 (11), 4790-4800, 2006 | 67 | 2006 |
Wobble inosine tRNA modification is essential to cell cycle progression in G1/S and G2/M transitions in fission yeast S Tsutsumi, R Sugiura, Y Ma, H Tokuoka, K Ohta, R Ohte, A Noma, ... Journal of biological chemistry 282 (46), 33459-33465, 2007 | 59 | 2007 |
Transient Receptor Potential (TRP) and Cch1-Yam8 Channels Play Key Roles in the Regulation of Cytoplasmic Ca2+ in Fission Yeast Y Ma, R Sugiura, A Koike, H Ebina, SO Sio, T Kuno PloS one 6 (7), e22421, 2011 | 58 | 2011 |
Its8, a fission yeast homolog of Mcd4 and Pig-n, is involved in GPI anchor synthesis and shares an essential function with calcineurin in cytokinesis T Yada, R Sugiura, A Kita, Y Itoh, Y Lu, Y Hong, T Kinoshita, H Shuntoh, ... Journal of Biological Chemistry 276 (17), 13579-13586, 2001 | 45 | 2001 |
Cation diffusion facilitator Cis4 is implicated in Golgi membrane trafficking via regulating zinc homeostasis in fission yeast Y Fang, R Sugiura, Y Ma, T Yada-Matsushima, H Umeno, T Kuno Molecular biology of the cell 19 (4), 1295-1303, 2008 | 44 | 2008 |
The role of the regulatory subunit of fission yeast calcineurin for in vivo activity and its relevance to FK506 sensitivity SO Sio, T Suehiro, R Sugiura, M Takeuchi, H Mukai, T Kuno Journal of Biological Chemistry 280 (13), 12231-12238, 2005 | 44 | 2005 |