| Cysteine proteases as therapeutic targets: does selectivity matter? A systematic review of calpain and cathepsin inhibitors M Siklos, M BenAissa, GRJ Thatcher Acta Pharmaceutica Sinica B 5 (6), 506-519, 2015 | 280 | 2015 |
| APOE‐modulated Aβ‐induced neuroinflammation in Alzheimer's disease: current landscape, novel data, and future perspective LM Tai, S Ghura, KP Koster, V Liakaite, M Maienschein‐Cline, P Kanabar, ... Journal of neurochemistry 133 (4), 465-488, 2015 | 175 | 2015 |
| APOE4 enhances age-dependent decline in cognitive function by down-regulating an NMDA receptor pathway in EFAD-Tg mice D Liu, X Pan, J Zhang, H Shen, NC Collins, AM Cole, KP Koster, ... Molecular neurodegeneration 10, 1-17, 2015 | 101 | 2015 |
| Amyloid-β pathology and APOE genotype modulate retinoid X receptor agonist activity in vivo LM Tai, KP Koster, J Luo, SH Lee, Y Wang, NC Collins, MB Aissa, ... Journal of Biological Chemistry 289 (44), 30538-30555, 2014 | 100 | 2014 |
| Soluble guanylyl cyclase is a critical regulator of migraine-associated pain M Ben Aissa, AF Tipton, Z Bertels, R Gandhi, LS Moye, M Novack, ... Cephalalgia 38 (8), 1471-1484, 2018 | 58 | 2018 |
| Pharmacological manipulation of cGMP and NO/cGMP in CNS drug discovery MA Hollas, MB Aissa, SH Lee, JM Gordon-Blake, GRJ Thatcher Nitric Oxide 82, 59-74, 2019 | 49 | 2019 |
| A multifunctional therapeutic approach to disease modification in multiple familial mouse models and a novel sporadic model of Alzheimer’s disease J Luo, SH Lee, L VandeVrede, Z Qin, M Ben Aissa, J Larson, AF Teich, ... Molecular Neurodegeneration 11, 1-14, 2016 | 44 | 2016 |
| A new type of scorpion Na+-channel-toxin-like polypeptide active on K+ channels N Srairi-Abid, JI Guijarro, R Benkhalifa, M Mantegazza, A Cheikh, ... Biochemical Journal 388 (2), 455-464, 2005 | 43 | 2005 |
| Targeting NO/cGMP Signaling in the CNS for Neurodegeneration and Alzheimer’s Disease MB aissa Current Medicinal Chemistry 23 (24), 19, 2016 | 41 | 2016 |
| Activation of Nrf2 and hypoxic adaptive response contribute to neuroprotection elicited by phenylhydroxamic acid selective HDAC6 inhibitors IN Gaisina, SH Lee, NA Kaidery, M Ben Aissa, M Ahuja, NN Smirnova, ... ACS chemical neuroscience 9 (5), 894-900, 2018 | 33 | 2018 |
| Discovery of nonlipogenic ABCA1 inducing compounds with potential in Alzheimer’s disease and type 2 diabetes M Ben Aissa, CT Lewandowski, KM Ratia, SH Lee, BT Layden, MJ LaDu, ... ACS Pharmacology & Translational Science 4 (1), 143-154, 2021 | 23 | 2021 |
| Interaction of oxidative stress and neurotrauma in ALDH2−/− mice causes significant and persistent behavioral and pro-inflammatory effects in a tractable model of mild … RC Knopp, SH Lee, M Hollas, E Nepomuceno, D Gonzalez, K Tam, ... Redox biology 32, 101486, 2020 | 23 | 2020 |
| Overexpression of quality control proteins reduces prion conversion in prion-infected cells S Thapa, B Abdulrahman, DH Abdelaziz, L Lu, MB Aissa, HM Schatzl Journal of Biological Chemistry 293 (41), 16069-16082, 2018 | 21 | 2018 |
| Re-engineering a neuroprotective, clinical drug as a procognitive agent with high in vivo potency and with GABAA potentiating activity for use in dementia J Luo, SH Lee, L VandeVrede, Z Qin, S Piyankarage, E Tavassoli, ... BMC neuroscience 16, 1-10, 2015 | 16 | 2015 |
| The Fanconi anemia group C protein interacts with uncoordinated 5A and delays apoptosis FF Huang, M Ben Aissa, A Magron, CC Huard, C Godin, G Levesque, ... PloS one 9 (3), e92811, 2014 | 14 | 2014 |
| Metabolomic analysis of a selective ABCA1 inducer in obesogenic challenge provides a rationale for therapeutic development CT Lewandowski, MW Khan, M BenAissa, O Dubrovskyi, ... EBioMedicine 66, 2021 | 11 | 2021 |
| Silencing of amyloid precursor protein expression using a new engineered delta ribozyme M Ben Aissa, MC April, LJ Bergeron, JP Perreault, G Levesque International Journal of Alzheimer’s Disease 2012 (1), 947147, 2012 | 6 | 2012 |
| P1‐083: NOVEL NAMPT ACTIVATORS ATTENUATE NEUROTOXICITY AND NEUROINFLAMMATION ASSOCIATED WITH NEURODEGENERATION J Gordon-Blake, B Karumudi, K Ratia, RC Knopp, K Dye, M Ben Aissa, ... Alzheimer's & Dementia 15, P266-P267, 2019 | 4 | 2019 |
| FANCC localizes with UNC5A at neurite outgrowth and promotes neuritogenesis FF Huang, M Ben Aissa, G Lévesque, M Carreau BMC Research Notes 11, 1-7, 2018 | 4 | 2018 |
| Compounds, compositions, and methods for treating type 2 diabetes and dementia GR Thatcher, CT Lewandowski, MBEN AISSA, B Layden, YJ Shaw, ... US Patent App. 18/280,531, 2024 | | 2024 |
