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Paul DW Kirk
Paul DW Kirk
在 mrc-bsu.cam.ac.uk 的电子邮件经过验证 - 首页
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Community assessment to advance computational prediction of cancer drug combinations in a pharmacogenomic screen
MP Menden, D Wang, MJ Mason, B Szalai, KC Bulusu, Y Guan, T Yu, ...
Nature communications 10 (1), 2674, 2019
317*2019
A fast and efficient colocalization algorithm for identifying shared genetic risk factors across multiple traits
CN Foley, JR Staley, PG Breen, BB Sun, PDW Kirk, S Burgess, ...
Nature communications 12 (1), 764, 2021
2642021
Bayesian correlated clustering to integrate multiple datasets
P Kirk, JE Griffin, RS Savage, Z Ghahramani, DL Wild
Bioinformatics 28 (24), 3290-3297, 2012
2562012
A framework for parameter estimation and model selection from experimental data in systems biology using approximate Bayesian computation
J Liepe, P Kirk, S Filippi, T Toni, CP Barnes, MPH Stumpf
Nature protocols 9 (2), 439-456, 2014
2492014
ABC-SysBio—approximate Bayesian computation in Python with GPU support
J Liepe, C Barnes, E Cule, K Erguler, P Kirk, T Toni, MPH Stumpf
Bioinformatics 26 (14), 1797-1799, 2010
1822010
Model selection in systems and synthetic biology
P Kirk, T Thorne, MPH Stumpf
Current opinion in biotechnology 24 (4), 767-774, 2013
1482013
A comprehensive evaluation of nasal and bronchial cytokines and chemokines following experimental rhinovirus infection in allergic asthma: increased interferons (IFN-γ and IFN …
TT Hansel, T Tunstall, MB Trujillo-Torralbo, B Shamji, A Del-Rosario, ...
EBioMedicine 19, 128-138, 2017
1282017
Topological sensitivity analysis for systems biology
AC Babtie, P Kirk, MPH Stumpf
Proceedings of the National Academy of Sciences 111 (52), 18507-18512, 2014
1112014
Gaussian process regression bootstrapping: exploring the effects of uncertainty in time course data
PDW Kirk, MPH Stumpf
Bioinformatics 25 (10), 1300-1306, 2009
992009
The RNA landscape of the human placenta in health and disease
S Gong, F Gaccioli, J Dopierala, U Sovio, E Cook, PJ Volders, L Martens, ...
Nature Communications 12 (1), 2639, 2021
982021
Systems biology (un) certainties
PDW Kirk, AC Babtie, MPH Stumpf
Science 350 (6259), 386-388, 2015
912015
A general moment expansion method for stochastic kinetic models
A Ale, P Kirk, MPH Stumpf
The Journal of chemical physics 138 (17), 2013
842013
Network topology and parameter estimation: from experimental design methods to gene regulatory network kinetics using a community based approach
P Meyer, T Cokelaer, D Chandran, KH Kim, PR Loh, G Tucker, M Lipson, ...
BMC systems biology 8, 1-18, 2014
812014
Multivariate moment closure techniques for stochastic kinetic models
E Lakatos, A Ale, PDW Kirk, MPH Stumpf
The Journal of chemical physics 143 (9), 2015
802015
Bayesian hierarchical clustering for microarray time series data with replicates and outlier measurements
EJ Cooke, RS Savage, PDW Kirk, R Darkins, DL Wild
BMC bioinformatics 12, 1-12, 2011
792011
Model selection in systems biology depends on experimental design
D Silk, PDW Kirk, CP Barnes, T Toni, MPH Stumpf
PLoS computational biology 10 (6), e1003650, 2014
742014
Longitudinal proteomic profiling of dialysis patients with COVID-19 reveals markers of severity and predictors of death
J Gisby, CL Clarke, N Medjeral-Thomas, TH Malik, A Papadaki, ...
Elife 10, e64827, 2021
702021
Robustness of MEK-ERK dynamics and origins of cell-to-cell variability in MAPK signaling
S Filippi, CP Barnes, PDW Kirk, T Kudo, K Kunida, SS McMahon, ...
Cell reports 15 (11), 2524-2535, 2016
672016
MR-Clust: clustering of genetic variants in Mendelian randomization with similar causal estimates
CN Foley, AM Mason, PDW Kirk, S Burgess
Bioinformatics 37 (4), 531-541, 2021
612021
A Bayesian mixture modelling approach for spatial proteomics
OM Crook, CM Mulvey, PDW Kirk, KS Lilley, L Gatto
PLoS computational biology 14 (11), e1006516, 2018
602018
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