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Gael Menasche
Gael Menasche
INSERU U1163/ Institut Imagine
在 inserm.fr 的电子邮件经过验证 - 首页
标题
引用次数
引用次数
年份
Mutations in RAB27A cause Griscelli syndrome associated with haemophagocytic syndrome
G Ménasché, E Pastural, J Feldmann, S Certain, F Ersoy, S Dupuis, ...
Nature genetics 25 (2), 173-176, 2000
10872000
Molecular mechanisms of biogenesis and exocytosis of cytotoxic granules
G de Saint Basile, G Ménasché, A Fischer
Nature Reviews Immunology 10 (8), 568-579, 2010
5192010
Munc18-2 deficiency causes familial hemophagocytic lymphohistiocytosis type 5 and impairs cytotoxic granule exocytosis in patient NK cells
M Côte, MM Ménager, A Burgess, N Mahlaoui, C Picard, C Schaffner, ...
The Journal of clinical investigation 119 (12), 3765-3773, 2009
4172009
Griscelli syndrome restricted to hypopigmentation results from a melanophilin defect (GS3) or a MYO5A F-exon deletion (GS1)
G Ménasché, CH Ho, O Sanal, J Feldmann, I Tezcan, F Ersoy, ...
The Journal of clinical investigation 112 (3), 450-456, 2003
3892003
Secretory cytotoxic granule maturation and exocytosis require the effector protein hMunc13-4
MM Ménager, G Ménasché, M Romao, P Knapnougel, CH Ho, M Garfa, ...
Nature immunology 8 (3), 257-267, 2007
3102007
Primary hemophagocytic syndromes point to a direct link between lymphocyte cytotoxicity and homeostasis
G Ménasché, J Feldmann, A Fischer, G De Saint Basile
Immunological reviews 203 (1), 165-179, 2005
2202005
Inherited defects in lymphocyte cytotoxic activity
JP Schmid, M Côte, MM Ménager, A Burgess, N Nehme, G Ménasché, ...
Immunological reviews 235 (1), 10-23, 2010
2032010
Rab27A and its effector MyRIP link secretory granules to F-actin and control their motion towards release sites
C Desnos, JS Schonn, S Huet, VS Tran, A El-Amraoui, G Raposo, ...
The Journal of cell biology 163 (3), 559-570, 2003
1962003
The ADAP/SKAP55 signaling module regulates T-cell receptor-mediated integrin activation through plasma membrane targeting of Rap1
S Kliche, D Breitling, M Togni, R Pusch, K Heuer, X Wang, C Freund, ...
Molecular and cellular biology 26 (19), 7130-7144, 2006
1542006
RIAM links the ADAP/SKAP-55 signaling module to Rap1, facilitating T-cell-receptor-mediated integrin activation
G Ménasché, S Kliche, EJH Chen, TEB Stradal, B Schraven, G Koretzky
Molecular and cellular biology, 2007
1362007
Terminal transport of lytic granules to the immune synapse is mediated by the kinesin-1/Slp3/Rab27a complex
M Kurowska, N Goudin, NT Nehme, M Court, J Garin, A Fischer, ...
Blood, The Journal of the American Society of Hematology 119 (17), 3879-3889, 2012
1282012
Biochemical and functional characterization of Rab27a mutations occurring in Griscelli syndrome patients
G Ménasché, J Feldmann, A Houdusse, C Desaymard, A Fischer, B Goud, ...
Blood, The Journal of the American Society of Hematology 101 (7), 2736-2742, 2003
1122003
Griscelli disease: genotype–phenotype correlation in an array of clinical heterogeneity
O Sanal, F Ersoy, I Tezcan, A Metin, L Yel, G Ménasché, A Gürgey, ...
Journal of clinical immunology 22, 237-243, 2002
1052002
Severe and progressive encephalitis as a presenting manifestation of a novel missense perforin mutation and impaired cytolytic activity
J Feldmann, G Ménasché, I Callebaut, V Minard-Colin, B Bader-Meunier, ...
Blood 105 (7), 2658-2663, 2005
1002005
A novel immunoregulatory role for NK-cell cytotoxicity in protection from HLH-like immunopathology in mice
FE Sepulveda, S Maschalidi, CAJ Vosshenrich, A Garrigue, M Kurowska, ...
Blood, The Journal of the American Society of Hematology 125 (9), 1427-1434, 2015
942015
Distinct severity of HLH in both human and murine mutants with complete loss of cytotoxic effector PRF1, RAB27A, and STX11
FE Sepulveda, F Debeurme, G Ménasché, M Kurowska, M Côte, ...
Blood, The Journal of the American Society of Hematology 121 (4), 595-603, 2013
892013
LYST controls the biogenesis of the endosomal compartment required for secretory lysosome function
FE Sepulveda, A Burgess, X Heiligenstein, N Goudin, MM Ménager, ...
Traffic 16 (2), 191-203, 2015
852015
Griscelli Syndrome: Characterization of a New Mutation and Rescue of T-Cytotoxic Activity by Retroviral Transfer of RAB27A Gene
JCS Bizario, J Feldmann, FA Castro, G Ménasché, CMA Jacob, ...
Journal of clinical immunology 24, 397-410, 2004
722004
A newly identified isoform of Slp2a associates with Rab27a in cytotoxic T cells and participates to cytotoxic granule secretion
G Ménasché, MM Ménager, JM Lefebvre, E Deutsch, R Athman, ...
Blood, The Journal of the American Society of Hematology 112 (13), 5052-5062, 2008
702008
Polygenic mutations in the cytotoxicity pathway increase susceptibility to develop HLH immunopathology in mice
FE Sepulveda, A Garrigue, S Maschalidi, M Garfa-Traore, G Ménasché, ...
Blood, The Journal of the American Society of Hematology 127 (17), 2113-2121, 2016
662016
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