Mutations in RAB27A cause Griscelli syndrome associated with haemophagocytic syndrome G Ménasché, E Pastural, J Feldmann, S Certain, F Ersoy, S Dupuis, ... Nature genetics 25 (2), 173-176, 2000 | 1087 | 2000 |
Molecular mechanisms of biogenesis and exocytosis of cytotoxic granules G de Saint Basile, G Ménasché, A Fischer Nature Reviews Immunology 10 (8), 568-579, 2010 | 519 | 2010 |
Munc18-2 deficiency causes familial hemophagocytic lymphohistiocytosis type 5 and impairs cytotoxic granule exocytosis in patient NK cells M Côte, MM Ménager, A Burgess, N Mahlaoui, C Picard, C Schaffner, ... The Journal of clinical investigation 119 (12), 3765-3773, 2009 | 417 | 2009 |
Griscelli syndrome restricted to hypopigmentation results from a melanophilin defect (GS3) or a MYO5A F-exon deletion (GS1) G Ménasché, CH Ho, O Sanal, J Feldmann, I Tezcan, F Ersoy, ... The Journal of clinical investigation 112 (3), 450-456, 2003 | 389 | 2003 |
Secretory cytotoxic granule maturation and exocytosis require the effector protein hMunc13-4 MM Ménager, G Ménasché, M Romao, P Knapnougel, CH Ho, M Garfa, ... Nature immunology 8 (3), 257-267, 2007 | 310 | 2007 |
Primary hemophagocytic syndromes point to a direct link between lymphocyte cytotoxicity and homeostasis G Ménasché, J Feldmann, A Fischer, G De Saint Basile Immunological reviews 203 (1), 165-179, 2005 | 220 | 2005 |
Inherited defects in lymphocyte cytotoxic activity JP Schmid, M Côte, MM Ménager, A Burgess, N Nehme, G Ménasché, ... Immunological reviews 235 (1), 10-23, 2010 | 203 | 2010 |
Rab27A and its effector MyRIP link secretory granules to F-actin and control their motion towards release sites C Desnos, JS Schonn, S Huet, VS Tran, A El-Amraoui, G Raposo, ... The Journal of cell biology 163 (3), 559-570, 2003 | 196 | 2003 |
The ADAP/SKAP55 signaling module regulates T-cell receptor-mediated integrin activation through plasma membrane targeting of Rap1 S Kliche, D Breitling, M Togni, R Pusch, K Heuer, X Wang, C Freund, ... Molecular and cellular biology 26 (19), 7130-7144, 2006 | 154 | 2006 |
RIAM links the ADAP/SKAP-55 signaling module to Rap1, facilitating T-cell-receptor-mediated integrin activation G Ménasché, S Kliche, EJH Chen, TEB Stradal, B Schraven, G Koretzky Molecular and cellular biology, 2007 | 136 | 2007 |
Terminal transport of lytic granules to the immune synapse is mediated by the kinesin-1/Slp3/Rab27a complex M Kurowska, N Goudin, NT Nehme, M Court, J Garin, A Fischer, ... Blood, The Journal of the American Society of Hematology 119 (17), 3879-3889, 2012 | 128 | 2012 |
Biochemical and functional characterization of Rab27a mutations occurring in Griscelli syndrome patients G Ménasché, J Feldmann, A Houdusse, C Desaymard, A Fischer, B Goud, ... Blood, The Journal of the American Society of Hematology 101 (7), 2736-2742, 2003 | 112 | 2003 |
Griscelli disease: genotype–phenotype correlation in an array of clinical heterogeneity O Sanal, F Ersoy, I Tezcan, A Metin, L Yel, G Ménasché, A Gürgey, ... Journal of clinical immunology 22, 237-243, 2002 | 105 | 2002 |
Severe and progressive encephalitis as a presenting manifestation of a novel missense perforin mutation and impaired cytolytic activity J Feldmann, G Ménasché, I Callebaut, V Minard-Colin, B Bader-Meunier, ... Blood 105 (7), 2658-2663, 2005 | 100 | 2005 |
A novel immunoregulatory role for NK-cell cytotoxicity in protection from HLH-like immunopathology in mice FE Sepulveda, S Maschalidi, CAJ Vosshenrich, A Garrigue, M Kurowska, ... Blood, The Journal of the American Society of Hematology 125 (9), 1427-1434, 2015 | 94 | 2015 |
Distinct severity of HLH in both human and murine mutants with complete loss of cytotoxic effector PRF1, RAB27A, and STX11 FE Sepulveda, F Debeurme, G Ménasché, M Kurowska, M Côte, ... Blood, The Journal of the American Society of Hematology 121 (4), 595-603, 2013 | 89 | 2013 |
LYST controls the biogenesis of the endosomal compartment required for secretory lysosome function FE Sepulveda, A Burgess, X Heiligenstein, N Goudin, MM Ménager, ... Traffic 16 (2), 191-203, 2015 | 85 | 2015 |
Griscelli Syndrome: Characterization of a New Mutation and Rescue of T-Cytotoxic Activity by Retroviral Transfer of RAB27A Gene JCS Bizario, J Feldmann, FA Castro, G Ménasché, CMA Jacob, ... Journal of clinical immunology 24, 397-410, 2004 | 72 | 2004 |
A newly identified isoform of Slp2a associates with Rab27a in cytotoxic T cells and participates to cytotoxic granule secretion G Ménasché, MM Ménager, JM Lefebvre, E Deutsch, R Athman, ... Blood, The Journal of the American Society of Hematology 112 (13), 5052-5062, 2008 | 70 | 2008 |
Polygenic mutations in the cytotoxicity pathway increase susceptibility to develop HLH immunopathology in mice FE Sepulveda, A Garrigue, S Maschalidi, M Garfa-Traore, G Ménasché, ... Blood, The Journal of the American Society of Hematology 127 (17), 2113-2121, 2016 | 66 | 2016 |