Glutamine blockade induces divergent metabolic programs to overcome tumor immune evasion RD Leone, L Zhao, JM Englert, IM Sun, MH Oh, IH Sun, ML Arwood, ... Science 366 (6468), 1013-1021, 2019 | 766 | 2019 |
Multi-tissue interactions in an integrated three-tissue organ-on-a-chip platform A Skardal, SV Murphy, M Devarasetty, I Mead, HW Kang, YJ Seol, ... Scientific reports 7 (1), 8837, 2017 | 497 | 2017 |
Targeting glutamine metabolism enhances tumor-specific immunity by modulating suppressive myeloid cells MH Oh, IH Sun, L Zhao, RD Leone, IM Sun, W Xu, SL Collins, AJ Tam, ... The Journal of clinical investigation 130 (7), 3865-3884, 2020 | 265 | 2020 |
Combination therapy with BPTES nanoparticles and metformin targets the metabolic heterogeneity of pancreatic cancer A Elgogary, Q Xu, B Poore, J Alt, SC Zimmermann, L Zhao, J Fu, B Chen, ... Proceedings of the National Academy of Sciences 113 (36), E5328-E5336, 2016 | 223 | 2016 |
toxicometabolomics M Bouhifd, T Hartung, HT Hogberg, A Kleensang, L Zhao Journal of Applied Toxicology 33 (12), 1365-1383, 2013 | 194 | 2013 |
Rotenone exerts developmental neurotoxicity in a human brain spheroid model D Pamies, K Block, P Lau, L Gribaldo, CA Pardo, P Barreras, L Smirnova, ... Toxicology and applied pharmacology 354, 101-114, 2018 | 128 | 2018 |
mTOR complex 1 signaling regulates the generation and function of central and effector Foxp3+ regulatory T cells IH Sun, MH Oh, L Zhao, CH Patel, ML Arwood, W Xu, AJ Tam, RL Blosser, ... The Journal of Immunology 201 (2), 481-492, 2018 | 123 | 2018 |
The antifungal drug itraconazole targets VDAC1 to modulate the AMPK/mTOR signaling axis in endothelial cells S Head, W Shi, L Zhao, G K., K Pasunooti, Y Chen, Z Deng, R Li, JS Shim, ... Proceedings of the National Academy of Sciences, 2015 | 121 | 2015 |
An engineered IL-2 partial agonist promotes CD8+ T cell stemness F Mo, Z Yu, P Li, J Oh, R Spolski, L Zhao, CR Glassman, TN Yamamoto, ... Nature 597 (7877), 544-548, 2021 | 117 | 2021 |
Transcriptional and metabolic adaptation of human neurons to the mitochondrial toxicant MPP+ AK Krug, S Gutbier, L Zhao, D Pöltl, C Kullmann, V Ivanova, S Förster, ... Cell death & disease 5 (5), e1222-e1222, 2014 | 114 | 2014 |
Pyriform spidroin 1, a novel member of the silk gene family that anchors dragline silk fibers in attachment discs of the black widow spider, Latrodectus hesperus E Blasingame, T Tuton-Blasingame, L Larkin, AM Falick, L Zhao, J Fong, ... Journal of biological chemistry 284 (42), 29097-29108, 2009 | 109 | 2009 |
t4 workshop report: pathways of toxicity A Kleensang, A Maertens, M Rosenberg, S Fitzpatrick, J Lamb, ... Altex 31 (1), 53, 2014 | 107 | 2014 |
C9orf72 regulates energy homeostasis by stabilizing mitochondrial complex I assembly T Wang, H Liu, K Itoh, S Oh, L Zhao, D Murata, H Sesaki, T Hartung, ... Cell Metabolism 33 (3), 531-546. e9, 2021 | 102 | 2021 |
Genetic variability in a frozen batch of MCF-7 cells invisible in routine authentication affecting cell function A Kleensang, MM Vantangoli, S Odwin-DaCosta, ME Andersen, ... Scientific reports 6 (1), 1-11, 2016 | 102 | 2016 |
Uncovering the Role of N-Acetyl-Aspartyl-Glutamate as a Glutamate Reservoir in Cancer T Nguyen, BJ Kirsch, R Asaka, K Nabi, A Quinones, J Tan, MJ Antonio, ... Cell Reports 27 (2), 491-501. e6, 2019 | 88 | 2019 |
Loss of Hepatic Mitochondrial Long-Chain Fatty Acid Oxidation Confers Resistance to Diet-Induced Obesity and Glucose Intolerance J Lee, J Choi, ESS Alpergin, L Zhao, T Hartung, S Scafidi, RC Riddle, ... Cell Reports 20 (3), 655-667, 2017 | 86 | 2017 |
Synthetic Spider Silk Fibers Spun from Pyriform Spidroin 2, A Glue Silk Protein Discovered in Orb-Weaving Spider Attachment Discs† P Geurts, L Zhao, Y Hsia, E Gnesa, S Tang, F Jeffery, CL Mattina, A Franz, ... Biomacromolecules 11 (12), 3495-3503, 2010 | 77 | 2010 |
The human toxome project M Bouhifd, ME Andersen, C Baghdikian, K Boekelheide, KM Crofton, ... Altex 32 (2), 112, 2015 | 75 | 2015 |
The mammalian malonyl-CoA synthetase ACSF3 is required for mitochondrial protein malonylation and metabolic efficiency CE Bowman, S Rodriguez, ESS Alpergin, MG Acoba, L Zhao, T Hartung, ... Cell chemical biology 24 (6), 673-684. e4, 2017 | 73 | 2017 |
Mapping the human toxome by systems toxicology M Bouhifd, HT Hogberg, A Kleensang, A Maertens, L Zhao, T Hartung Basic & clinical pharmacology & toxicology 115 (1), 24-31, 2014 | 61 | 2014 |