Dynamic redox control of NF-κB through glutaredoxin-regulated S-glutathionylation of inhibitory κB kinase β NL Reynaert, A van der Vliet, AS Guala, T McGovern, M Hristova, ... Proceedings of the National Academy of Sciences 103 (35), 13086-13091, 2006 | 492 | 2006 |
Nitric oxide represses inhibitory κB kinase through S-nitrosylation NL Reynaert, K Ckless, SH Korn, N Vos, AS Guala, EFM Wouters, ... Proceedings of the National Academy of Sciences 101 (24), 8945-8950, 2004 | 452 | 2004 |
Redox-sensitive kinases of the nuclear factor-κB signaling pathway C Pantano, NL Reynaert, AVD Vliet, YMW Janssen–Heininger Antioxidants & redox signaling 8 (9-10), 1791-1806, 2006 | 377 | 2006 |
Systemic and local inflammation in asthma and chronic obstructive pulmonary disease: is there a connection? EFM Wouters, NL Reynaert, MA Dentener, JHJ Vernooy Proceedings of the American Thoracic Society 6 (8), 638-647, 2009 | 203 | 2009 |
Silica induces NLRP3 inflammasome activation in human lung epithelial cells PM Peeters, TN Perkins, EFM Wouters, BT Mossman, NL Reynaert Particle and fibre toxicology 10, 1-11, 2013 | 180 | 2013 |
Systemic soluble receptor for advanced glycation endproducts is a biomarker of emphysema and associated with AGER genetic variants in patients with chronic obstructive … DT Cheng, DK Kim, DA Cockayne, A Belousov, H Bitter, MH Cho, ... American journal of respiratory and critical care medicine 188 (8), 948-957, 2013 | 175 | 2013 |
Redox amplification of apoptosis by caspase-dependent cleavage of glutaredoxin 1 and S-glutathionylation of Fas V Anathy, SW Aesif, AS Guala, M Havermans, NL Reynaert, YS Ho, ... Journal of Cell Biology 184 (2), 241-252, 2009 | 145 | 2009 |
Nuclear factor κB, airway epithelium, and asthma: avenues for redox control YMW Janssen-Heininger, ME Poynter, SW Aesif, C Pantano, JL Ather, ... Proceedings of the American Thoracic Society 6 (3), 249-255, 2009 | 136 | 2009 |
Silica-induced NLRP3 inflammasome activation in vitro and in rat lungs PM Peeters, IMJ Eurlings, TN Perkins, EF Wouters, RPF Schins, ... Particle and fibre toxicology 11, 1-15, 2014 | 122 | 2014 |
Advanced glycation end products and their receptor in age-related, non-communicable chronic inflammatory diseases; Overview of clinical evidence and potential contributions to … NL Reynaert, P Gopal, EPA Rutten, EFM Wouters, CG Schalkwijk The international journal of biochemistry & cell biology 81, 403-418, 2016 | 118 | 2016 |
Strong upregulation of AIM2 and IFI16 inflammasomes in the mucosa of patients with active inflammatory bowel disease W Vanhove, PM Peeters, D Staelens, A Schraenen, J Van der Goten, ... Inflammatory bowel diseases 21 (11), 2673-2682, 2015 | 118 | 2015 |
Various mechanistic pathways representing the aging process are altered in COPD EPA Rutten, P Gopal, EFM Wouters, FME Franssen, GJ Hageman, ... Chest 149 (1), 53-61, 2016 | 100 | 2016 |
Reactive nitrogen species and cell signaling: implications for death or survival of lung epithelium YMW Janssen-Heininger, RL Persinger, SH Korn, C Pantano, ... American journal of respiratory and critical care medicine 166 (supplement_1 …, 2002 | 93 | 2002 |
Modulation of glutaredoxin-1 expression in a mouse model of allergic airway disease NL Reynaert, EFM Wouters, YMW Janssen-Heininger American journal of respiratory cell and molecular biology 36 (2), 147-151, 2007 | 87 | 2007 |
In situ detection of S-glutathionylated proteins following glutaredoxin-1 catalyzed cysteine derivatization NL Reynaert, K Ckless, AS Guala, EFM Wouters, A van der Vliet, ... Biochimica et Biophysica Acta (BBA)-General Subjects 1760 (3), 380-387, 2006 | 85 | 2006 |
Differences in gene expression and cytokine production by crystalline vs. amorphous silica in human lung epithelial cells TN Perkins, A Shukla, PM Peeters, JL Steinbacher, CC Landry, ... Particle and fibre toxicology 9, 1-18, 2012 | 81 | 2012 |
Cigarette smoke extract induced exosome release is mediated by depletion of exofacial thiols and can be inhibited by thiol-antioxidants BJ Benedikter, C Volgers, PH van Eijck, EFM Wouters, PHM Savelkoul, ... Free Radical Biology and Medicine 108, 334-344, 2017 | 73 | 2017 |
Association of plasma sRAGE, but not esRAGE with lung function impairment in COPD P Gopal, NL Reynaert, JLJM Scheijen, CG Schalkwijk, FME Franssen, ... Respiratory research 15, 1-8, 2014 | 71 | 2014 |
Similar matrix alterations in alveolar and small airway walls of COPD patients IMJ Eurlings, MA Dentener, JPM Cleutjens, CJ Peutz, GGU Rohde, ... BMC pulmonary medicine 14, 1-11, 2014 | 68 | 2014 |
Plasma advanced glycation end-products and skin autofluorescence are increased in COPD P Gopal, NL Reynaert, JLJM Scheijen, L Engelen, CG Schalkwijk, ... European Respiratory Journal 43 (2), 430-438, 2014 | 62 | 2014 |