Analysis of the coding genome of diffuse large B-cell lymphoma L Pasqualucci, V Trifonov, G Fabbri, J Ma, D Rossi, A Chiarenza, ... Nature genetics 43 (9), 830-837, 2011 | 1148 | 2011 |
Transforming fusions of FGFR and TACC genes in human glioblastoma D Singh, JM Chan, P Zoppoli, F Niola, R Sullivan, A Castano, EM Liu, ... Science 337 (6099), 1231-1235, 2012 | 806 | 2012 |
The integrated landscape of driver genomic alterations in glioblastoma V Frattini, V Trifonov, JM Chan, A Castano, M Lia, F Abate, ST Keir, AX Ji, ... Nature genetics 45 (10), 1141-1149, 2013 | 598 | 2013 |
The human tumor atlas network: charting tumor transitions across space and time at single-cell resolution O Rozenblatt-Rosen, A Regev, P Oberdoerffer, T Nawy, A Hupalowska, ... Cell 181 (2), 236-249, 2020 | 397 | 2020 |
Topology of viral evolution JM Chan, G Carlsson, R Rabadan Proceedings of the National Academy of Sciences 110 (46), 18566-18571, 2013 | 339 | 2013 |
Lineage plasticity in cancer: a shared pathway of therapeutic resistance Á Quintanal-Villalonga, JM Chan, HA Yu, D Pe’er, CL Sawyers, T Sen, ... Nature reviews Clinical oncology 17 (6), 360-371, 2020 | 333 | 2020 |
Whole-exome sequencing identifies somatic mutations of BCOR in acute myeloid leukemia with normal karyotype V Grossmann, E Tiacci, AB Holmes, A Kohlmann, MP Martelli, W Kern, ... Blood, The Journal of the American Society of Hematology 118 (23), 6153-6163, 2011 | 296 | 2011 |
Tumor Analyses Reveal Squamous Transformation and Off-Target Alterations As Early Resistance Mechanisms to First-line Osimertinib in EGFR-Mutant Lung Cancer AJ Schoenfeld, JM Chan, D Kubota, H Sato, H Rizvi, Y Daneshbod, ... Clinical Cancer Research 26 (11), 2654-2663, 2020 | 277 | 2020 |
Concurrent RB1 and TP53 alterations define a subset of EGFR-mutant lung cancers at risk for histologic transformation and inferior clinical outcomes M Offin, JM Chan, M Tenet, HA Rizvi, R Shen, GJ Riely, N Rekhtman, ... Journal of Thoracic Oncology 14 (10), 1784-1793, 2019 | 275 | 2019 |
Emergence of fatal avian influenza in New England harbor seals SJ Anthony, JA St. Leger, K Pugliares, HS Ip, JM Chan, ZW Carpenter, ... MBio 3 (4), 10.1128/mbio. 00166-12, 2012 | 209 | 2012 |
Signatures of plasticity, metastasis, and immunosuppression in an atlas of human small cell lung cancer JM Chan, A Quintanal-Villalonga, VR Gao, Y Xie, V Allaj, O Chaudhary, ... Cancer cell 39 (11), 1479-1496. e18, 2021 | 204 | 2021 |
Lineage plasticity in prostate cancer depends on JAK/STAT inflammatory signaling JM Chan, S Zaidi, JR Love, JL Zhao, M Setty, KM Wadosky, A Gopalan, ... Science 377 (6611), 1180-1191, 2022 | 132 | 2022 |
Tim-4+ cavity-resident macrophages impair anti-tumor CD8+ T cell immunity A Chow, S Schad, MD Green, MD Hellmann, V Allaj, N Ceglia, G Zago, ... Cancer Cell 39 (7), 973-988. e9, 2021 | 119 | 2021 |
Multiomic analysis of lung tumors defines pathways activated in neuroendocrine transformation A Quintanal-Villalonga, H Taniguchi, YA Zhan, MM Hasan, SS Chavan, ... Cancer discovery 11 (12), 3028-3047, 2021 | 83 | 2021 |
The miR-424 (322)/503 cluster orchestrates remodeling of the epithelium in the involuting mammary gland D Llobet-Navas, R Rodríguez-Barrueco, V Castro, AP Ugalde, P Sumazin, ... Genes & development 28 (7), 765-782, 2014 | 83 | 2014 |
Transcriptional dissection of melanoma identifies a high-risk subtype underlying TP53 family genes and epigenome deregulation B Badal, A Solovyov, S Di Cecilia, JM Chan, LW Chang, R Iqbal, IT Aydin, ... JCI insight 2 (9), 2017 | 57 | 2017 |
Network analysis of global influenza spread J Chan, A Holmes, R Rabadan PLoS computational biology 6 (11), e1001005, 2010 | 54 | 2010 |
WEE1 inhibition enhances the antitumor immune response to PD-L1 blockade by the concomitant activation of STING and STAT1 pathways in SCLC H Taniguchi, R Caeser, SS Chavan, YA Zhan, A Chow, P Manoj, F Uddin, ... Cell reports 39 (7), 2022 | 48 | 2022 |
Targeting lysine-specific demethylase 1 rescues major histocompatibility complex class I antigen presentation and overcomes programmed death-ligand 1 blockade resistance in SCLC EM Nguyen, H Taniguchi, JM Chan, YA Zhan, X Chen, J Qiu, ... Journal of Thoracic Oncology 17 (8), 1014-1031, 2022 | 43 | 2022 |
The ectonucleotidase CD39 identifies tumor-reactive CD8+ T cells predictive of immune checkpoint blockade efficacy in human lung cancer A Chow, FZ Uddin, M Liu, A Dobrin, BY Nabet, L Mangarin, Y Lavin, ... Immunity 56 (1), 93-106. e6, 2023 | 39 | 2023 |