A novel rabbit model of Duchenne muscular dystrophy generated by CRISPR/Cas9 T Sui, YS Lau, D Liu, T Liu, L Xu, Y Gao, L Lai, Z Li, R Han Disease models & mechanisms 11 (6), dmm032201, 2018 | 90 | 2018 |
Boldine protects endothelial function in hyperglycemia-induced oxidative stress through an antioxidant mechanism YS Lau, XY Tian, Y Huang, D Murugan, FI Achike, MR Mustafa Biochemical pharmacology 85 (3), 367-375, 2013 | 84 | 2013 |
Boldine improves endothelial function in diabetic db/db mice through inhibition of angiotensin II‐mediated BMP4‐oxidative stress cascade YS Lau, XY Tian, MR Mustafa, D Murugan, J Liu, Y Zhang, CW Lau, ... British journal of pharmacology 170 (6), 1190-1198, 2013 | 63 | 2013 |
Boldine ameliorates vascular oxidative stress and endothelial dysfunction: Therapeutic implication for hypertension and diabetes YS Lau, WC Ling, D Murugan, MR Mustafa Journal of Cardiovascular Pharmacology 65 (6), 522-531, 2015 | 59 | 2015 |
Angiotensin 1-7 protects against angiotensin II-induced endoplasmic reticulum stress and endothelial dysfunction via mas receptor D Murugan, YS Lau, WC Lau, MR Mustafa, Y Huang PloS one 10 (12), e0145413, 2015 | 58 | 2015 |
Paeonol protects against endoplasmic reticulum stress-induced endothelial dysfunction via AMPK/PPARδ signaling pathway KW Choy, MR Mustafa, YS Lau, J Liu, D Murugan, CW Lau, L Wang, ... Biochemical Pharmacology 116, 51-62, 2016 | 52 | 2016 |
Life-long AAV-mediated CRISPR genome editing in dystrophic heart improves cardiomyopathy without causing serious lesions in mdx mice L Xu, YS Lau, Y Gao, H Li, R Han Molecular Therapy 27 (8), 1407-1414, 2019 | 49 | 2019 |
Paeonol attenuates LPS-induced endothelial dysfunction and apoptosis by inhibiting BMP4 and TLR4 signaling simultaneously but independently KW Choy, YS Lau, D Murugan, PM Vanhoutte, MR Mustafa Journal of Pharmacology and Experimental Therapeutics 364 (3), 420-432, 2018 | 44 | 2018 |
Automated muscle histopathology analysis using CellProfiler YS Lau, L Xu, Y Gao, R Han Skeletal muscle 8, 1-9, 2018 | 43 | 2018 |
Sodium nitrite exerts an antihypertensive effect and improves endothelial function through activation of eNOS in the SHR WC Ling, DD Murugan, YS Lau, PM Vanhoutte, MR Mustafa Scientific Reports 6 (1), 33048, 2016 | 41 | 2016 |
Chronic treatment with paeonol improves endothelial function in mice through inhibition of endoplasmic reticulum stress-mediated oxidative stress KW Choy, YS Lau, D Murugan, MR Mustafa PLoS One 12 (5), e0178365, 2017 | 40 | 2017 |
The aporphine alkaloid boldine improves endothelial function in spontaneously hypertensive rats YS Lau, A Machha, FI Achike, D Murugan, MR Mustafa Experimental biology and medicine 237 (1), 93-98, 2012 | 39 | 2012 |
Development of muscular dystrophy in a CRISPR-engineered mutant rabbit model with frame-disrupting ANO5 mutations T Sui, L Xu, YS Lau, D Liu, T Liu, Y Gao, L Lai, R Han, Z Li Cell Death & Disease 9 (6), 609, 2018 | 36 | 2018 |
Apocynum venetum leaf extract, an antihypertensive herb, inhibits rat aortic contraction induced by angiotensin II: a nitric oxide and superoxide connection YS Lau, CY Kwan, TC Ku, WT Hsieh, HD Wang, S Nishibe, M Dharmani, ... Journal of ethnopharmacology 143 (2), 565-571, 2012 | 32 | 2012 |
Genome-wide CRISPR screen identifies LGALS2 as an oxidative stress-responsive gene with an inhibitory function on colon tumor growth H Li, L Zhao, YS Lau, C Zhang, R Han Oncogene 40 (1), 177-188, 2021 | 30 | 2021 |
Angiotensin II Causes β-Cell Dysfunction Through an ER Stress-Induced Proinflammatory Response SMH Chan, YS Lau, AA Miller, JM Ku, S Potocnik, JM Ye, OL Woodman, ... Endocrinology 158 (10), 3162-3173, 2017 | 29 | 2017 |
Sodium nitrite causes relaxation of the isolated rat aorta: By stimulating both endothelial NO synthase and activating soluble guanylyl cyclase in vascular smooth muscle WC Ling, YS Lau, DD Murugan, PM Vanhoutte, MR Mustafa Vascular pharmacology 74, 87-92, 2015 | 29 | 2015 |
3′, 4′-dihydroxyflavonol ameliorates endoplasmic reticulum stress-induced apoptosis and endothelial dysfunction in mice YS Lau, MR Mustafa, KW Choy, SMH Chan, S Potocnik, TP Herbert, ... Scientific Reports 8 (1), 1818, 2018 | 28 | 2018 |
Renal targeting potential of a polymeric drug carrier, poly-l-glutamic acid, in normal and diabetic rats HJ Chai, LV Kiew, Y Chin, A Norazit, S Mohd Noor, YL Lo, CY Looi, ... International Journal of Nanomedicine, 577-591, 2017 | 19 | 2017 |
Endothelium-Dependent Relaxation Effect of Apocynum venetum Leaf Extract via Src/PI3K/Akt Signalling Pathway YS Lau, WC Ling, D Murugan, CY Kwan, MR Mustafa Nutrients 7 (7), 5239-5253, 2015 | 14 | 2015 |