Electronic health record-based genome-wide meta-analysis provides insights on the genetic architecture of non-alcoholic fatty liver disease N Ghodsian, E Abner, CA Emdin, E Gobeil, N Taba, ME Haas, N Perrot, ... Cell Reports Medicine 2 (11), 2021 | 102 | 2021 |
Genetic and In Vitro Inhibition of PCSK9 and Calcific Aortic Valve Stenosis N Perrot, V Valerio, D Moschetta, SM Boekholdt, C Dina, HY Chen, ... Basic to Translational Science 5 (7), 649-661, 2020 | 63 | 2020 |
International union of basic and clinical pharmacology. CIX. Differences and similarities between human and rodent prostaglandin E2 receptors (EP1–4) and prostacyclin receptor … X Norel, Y Sugimoto, G Ozen, H Abdelazeem, Y Amgoud, A Bouhadoun, ... Pharmacological reviews 72 (4), 910-968, 2020 | 34 | 2020 |
Impact of the gut microbiota and associated metabolites on cardiometabolic traits, chronic diseases and human longevity: a Mendelian randomization study E Gagnon, PL Mitchell, HD Manikpurage, E Abner, N Taba, T Esko, ... Journal of Translational Medicine 21 (1), 60, 2023 | 30 | 2023 |
Polygenic risk score for coronary artery disease improves the prediction of early-onset myocardial infarction and mortality in men HD Manikpurage, A Eslami, N Perrot, Z Li, C Couture, P Mathieu, Y Bossé, ... Circulation: Genomic and Precision Medicine 14 (6), e003452, 2021 | 27 | 2021 |
Mendelian randomization analysis identifies blood tyrosine levels as a biomarker of non-alcoholic fatty liver disease É Gobeil, I Maltais-Payette, N Taba, F Brière, N Ghodsian, E Abner, ... Metabolites 12 (5), 440, 2022 | 21 | 2022 |
Proteome-wide Mendelian randomization identifies causal links between blood proteins and acute pancreatitis J Bourgault, E Abner, HD Manikpurage, N Pujol-Gualdo, T Laisk, É Gobeil, ... Gastroenterology 164 (6), 953-965. e3, 2023 | 20 | 2023 |
Sex-Specific Associations of Genetically Predicted Circulating Lp(a) (Lipoprotein(a)) and Hepatic LPA Gene Expression Levels With Cardiovascular Outcomes … J Guertin, Y Kaiser, H Manikpurage, N Perrot, R Bourgeois, C Couture, ... Circulation: Genomic and Precision Medicine 14 (4), e003271, 2021 | 13 | 2021 |
Mendelian randomization prioritizes abdominal adiposity as an independent causal factor for liver fat accumulation and cardiometabolic diseases E Gagnon, W Pelletier, É Gobeil, J Bourgault, HD Manikpurage, ... Communications Medicine 2 (1), 130, 2022 | 11 | 2022 |
Greater adherence to the 2019 Canada’s Food Guide recommendations on healthy food choices reduces the risk of cardiovascular disease in adults: a prospective analysis of UK … D Brassard, HD Manikpurage, S Thériault, BJ Arsenault, B Lamarche The American Journal of Clinical Nutrition 116 (6), 1748-1758, 2022 | 9 | 2022 |
Genetic inhibition of angiopoietin-like protein-3, lipids, and cardiometabolic risk É Gobeil, J Bourgault, PL Mitchell, U Houessou, E Gagnon, A Girard, ... European Heart Journal 45 (9), 707-721, 2024 | 6* | 2024 |
DHA, RvD1, RvD5, and MaR1 reduce human coronary arteries contractions induced by PGE2 A Bouhadoun, HD Manikpurage, C Deschildre, S Zalghout, ... Prostaglandins & Other Lipid Mediators 165, 106700, 2023 | 6 | 2023 |
Blood Levels of the SMOC1 Hepatokine Are Not Causally Linked with Type 2 Diabetes: A Bidirectional Mendelian Randomization Study N Ghodsian, E Gagnon, J Bourgault, É Gobeil, HD Manikpurage, N Perrot, ... Nutrients 13 (12), 4208, 2021 | 5 | 2021 |
Large-scale metabolomic profiling and incident non-alcoholic fatty liver disease E Gagnon, HD Manikpurage, PL Mitchell, A Girard, É Gobeil, J Bourgault, ... Iscience 26 (7), 2023 | 4 | 2023 |
Sex‐Specific Impact of Body Weight on Atherosclerotic Cardiovascular Disease Incidence in Individuals With and Without Ideal Cardiovascular Health A Paulin, HD Manikpurage, JP Després, S Thériault, BJ Arsenault Journal of the American Heart Association 12 (13), e028502, 2023 | 4 | 2023 |
Impact of C-reactive protein levels on lipoprotein (a)-associated aortic stenosis incidence and progression A Girard, E Gaillard, R Puri, R Capoulade, KL Chan, A Paulin, ... European heart journal open 3 (2), oead032, 2023 | 4 | 2023 |
Integrative genomic analyses identify candidate causal genes for calcific aortic valve stenosis involving tissue-specific regulation S Thériault, Z Li, E Abner, J Luan, HD Manikpurage, U Houessou, ... Nature communications 15 (1), 2407, 2024 | 2 | 2024 |
Contribution of Lipoprotein (a) to Polygenic Risk Prediction of Coronary Artery Disease: A Prospective UK Biobank Analysis HD Manikpurage, A Paulin, A Girard, A Eslami, P Mathieu, S Thériault, ... Circulation: Genomic and Precision Medicine 16 (5), 470-477, 2023 | 1 | 2023 |
In search of pulmonary hypertension treatments: Effect of 17β-estradiol on PGI2 pathway in human pulmonary artery Y Amgoud, A Senbel, A Bouhadoun, H Abdelazeem, G Ozen, I Savané, ... Prostaglandins, Leukotrienes and Essential Fatty Acids 172, 102321, 2021 | 1 | 2021 |
Polygenic inheritance and its interplay with smoking history in predicting lung cancer diagnosis: a French-Canadian case-control cohort V Boumtje, HD Manikpurage, Z Li, N Gaudreault, VS Armero, ... EBioMedicine 106, 2024 | | 2024 |