Pan-cancer analysis of whole genomes Nature 578 (7793), 82-93, 2020 | 1786* | 2020 |
The landscape of genomic alterations across childhood cancers SN Gröbner, BC Worst, J Weischenfeldt, I Buchhalter, K Kleinheinz, ... Nature 555 (7696), 321-327, 2018 | 1338 | 2018 |
The whole-genome landscape of medulloblastoma subtypes PA Northcott, I Buchhalter, AS Morrissy, V Hovestadt, J Weischenfeldt, ... Nature 547 (7663), 311-317, 2017 | 975 | 2017 |
Repressive and active histone methylation mark distinct promoters in human and mouse spermatozoa U Brykczynska, M Hisano, S Erkek, L Ramos, EJ Oakeley, TC Roloff, ... Nature structural & molecular biology 17 (6), 679-687, 2010 | 751 | 2010 |
Enhancer hijacking activates GFI1 family oncogenes in medulloblastoma PA Northcott, C Lee, T Zichner, AM Stütz, S Erkek, D Kawauchi, DJH Shih, ... Nature 511 (7510), 428-434, 2014 | 682 | 2014 |
In utero undernourishment perturbs the adult sperm methylome and intergenerational metabolism EJ Radford, M Ito, H Shi, JA Corish, K Yamazawa, E Isganaitis, ... Science 345 (6198), 1255903, 2014 | 673 | 2014 |
Atypical teratoid/rhabdoid tumors are comprised of three epigenetic subgroups with distinct enhancer landscapes PD Johann, S Erkek, M Zapatka, K Kerl, I Buchhalter, V Hovestadt, ... Cancer cell 29 (3), 379-393, 2016 | 534 | 2016 |
Disruption of histone methylation in developing sperm impairs offspring health transgenerationally K Siklenka, S Erkek, M Godmann, R Lambrot, S McGraw, C Lafleur, ... Science 350 (6261), aab2006, 2015 | 483 | 2015 |
Decoding the regulatory landscape of medulloblastoma using DNA methylation sequencing V Hovestadt, DTW Jones, S Picelli, W Wang, M Kool, PA Northcott, ... Nature 510 (7506), 537-541, 2014 | 440 | 2014 |
Active medulloblastoma enhancers reveal subgroup-specific cellular origins CY Lin, S Erkek, Y Tong, L Yin, AJ Federation, M Zapatka, P Haldipur, ... Nature 530 (7588), 57-62, 2016 | 398 | 2016 |
Pan-cancer analysis of somatic copy-number alterations implicates IRS4 and IGF2 in enhancer hijacking J Weischenfeldt, T Dubash, AP Drainas, BR Mardin, Y Chen, AM Stütz, ... Nature genetics 49 (1), 65-74, 2017 | 385 | 2017 |
Molecular determinants of nucleosome retention at CpG-rich sequences in mouse spermatozoa S Erkek, M Hisano, CY Liang, M Gill, R Murr, J Dieker, D Schübeler, ... Nature structural & molecular biology 20 (7), 868-875, 2013 | 364 | 2013 |
Genomic basis for RNA alterations in cancer PCAWG Transcriptome Core Group Calabrese Claudia 2 Davidson Natalie R. 3 4 5 ... Nature 578 (7793), 129-136, 2020 | 284 | 2020 |
Therapeutic targeting of ependymoma as informed by oncogenic enhancer profiling SC Mack, KW Pajtler, L Chavez, K Okonechnikov, KC Bertrand, X Wang, ... Nature 553 (7686), 101-105, 2018 | 199 | 2018 |
Genome-wide profiles of extra-cranial malignant rhabdoid tumors reveal heterogeneity and dysregulated developmental pathways HJE Chun, EL Lim, A Heravi-Moussavi, S Saberi, KL Mungall, M Bilenky, ... Cancer cell 29 (3), 394-406, 2016 | 131 | 2016 |
Sperm is epigenetically programmed to regulate gene transcription in embryos M Teperek, A Simeone, V Gaggioli, K Miyamoto, GE Allen, S Erkek, ... Genome research 26 (8), 1034-1046, 2016 | 129 | 2016 |
Identification and analyses of extra-cranial and cranial rhabdoid tumor molecular subgroups reveal tumors with cytotoxic T cell infiltration HJE Chun, PD Johann, K Milne, M Zapatka, A Buellesbach, N Ishaque, ... Cell reports 29 (8), 2338-2354. e7, 2019 | 86 | 2019 |
Genome-wide chromatin analysis in mature mouse and human spermatozoa M Hisano, S Erkek, S Dessus-Babus, L Ramos, MB Stadler, AHFM Peters Nature protocols 8 (12), 2449-2470, 2013 | 85 | 2013 |
Comprehensive analysis of chromatin states in atypical teratoid/rhabdoid tumor identifies diverging roles for SWI/SNF and polycomb in gene regulation S Erkek, PD Johann, MA Finetti, Y Drosos, HC Chou, M Zapatka, D Sturm, ... Cancer cell 35 (1), 95-110. e8, 2019 | 77 | 2019 |
Lsd1 as a therapeutic target in Gfi1-activated medulloblastoma C Lee, VA Rudneva, S Erkek, M Zapatka, LQ Chau, ... Nature communications 10 (1), 332, 2019 | 69 | 2019 |