| Cyclic ADP-Ribose in Insulin Secretion from Pancreatic βCells S Takasawa, K Nata, H Yonekura, H Okamoto Science 259 (5093), 370-373, 1993 | 521 | 1993 |
| Synthesis and hydrolysis of cyclic ADP-ribose by human leukocyte antigen CD38 and inhibition of the hydrolysis by ATP. S Takasawa, A Tohgo, N Noguchi, T Koguma, K Nata, T Sugimoto, ... Journal of Biological Chemistry 268 (35), 26052-26054, 1993 | 349 | 1993 |
| Cyclic ADP-ribose binds to FK506-binding protein 12.6 to release Ca2+ from islet microsomes N Noguchi, S Takasawa, K Nata, A Tohgo, I Kato, F Ikehata, H Yonekura, ... Journal of Biological Chemistry 272 (6), 3133-3136, 1997 | 253 | 1997 |
| Activation of Reg gene, a gene for insulin-producing β-cell regeneration: Poly(ADP-ribose) polymerase binds Reg promoter and regulates the transcription by … T Akiyama, S Takasawa, K Nata, S Kobayashi, M Abe, NJ Shervani, ... Proceedings of the National Academy of Sciences 98 (1), 48-53, 2001 | 235 | 2001 |
| Identification of a receptor for Reg (regenerating gene) protein, a pancreatic β-cell regeneration factor S Kobayashi, T Akiyama, K Nata, M Abe, M Tajima, NJ Shervani, M Unno, ... Journal of Biological Chemistry 275 (15), 10723-10726, 2000 | 217 | 2000 |
| Cyclic ADP-ribose and inositol 1, 4, 5-trisphosphate as alternate second messengers for intracellular Ca2+ mobilization in normal and diabetic β-cells S Takasawa, T Akiyama, K Nata, M Kuroki, A Tohgo, N Noguchi, ... Journal of Biological Chemistry 273 (5), 2497-2500, 1998 | 154 | 1998 |
| Regulatory Role of CD38 (ADP-ribosyl Cyclase/Cyclic ADP-ribose Hydrolase) in Insulin Secretion by Glucose in Pancreatic βCells: ENHANCED INSULIN SECRETION IN CD38-EXPRESSING … I Kato, S Takasawa, A Akabane, O Tanaka, H Abe, T Takamura, Y Suzuki, ... Journal of Biological Chemistry 270 (50), 30045-30050, 1995 | 154 | 1995 |
| Production and Characterization of Reg Knockout Mice: Reduced Proliferation of Pancreatic β-Cells in Reg Knockout Mice M Unno, K Nata, N Noguchi, Y Narushima, T Akiyama, T Ikeda, ... Diabetes 51 (suppl_3), S478-S483, 2002 | 153 | 2002 |
| Essential cysteine residues for cyclic ADP-ribose synthesis and hydrolysis by CD38. A Tohgo, S Takasawa, N Noguchi, T Koguma, K Nata, T Sugimoto, ... Journal of Biological Chemistry 269 (46), 28555-28557, 1994 | 147 | 1994 |
| Autoantibodies against CD38 (ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase) that impair glucose-induced insulin secretion in noninsulin-dependent diabetes patients. F Ikehata, J Satoh, K Nata, A Tohgo, T Nakazawa, I Kato, S Kobayashi, ... The Journal of clinical investigation 102 (2), 395-401, 1998 | 124 | 1998 |
| Important role of heparan sulfate in postnatal islet growth and insulin secretion I Takahashi, N Noguchi, K Nata, S Yamada, T Kaneiwa, S Mizumoto, ... Biochemical and biophysical research communications 383 (1), 113-118, 2009 | 119 | 2009 |
| Requirement of Calmodulindependent Protein Kinase II in Cyclic ADP-ribose-mediated Intracellular Ca2+ Mobilization (∗) S Takasawa, A Ishida, K Nata, K Nakagawa, N Noguchi, A Tohgo, I Kato, ... Journal of Biological Chemistry 270 (51), 30257-30259, 1995 | 119 | 1995 |
| Human gene encoding CD38 (ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase): organization, nucleotide sequence and alternative splicing K Nata, T Takamura, T Karasawa, T Kumagai, W Hashioka, A Tohgo, ... Gene 186 (2), 285-292, 1997 | 115 | 1997 |
| Identification of a novel Reg family gene, Reg IIIδ, and mapping of all three types of Reg family gene in a 75 kilobase mouse genomic region M Abe, K Nata, T Akiyama, NJ Shervani, S Kobayashi, ... Gene 246 (1-2), 111-122, 2000 | 108 | 2000 |
| Molecular cloning, expression and chromosomal localization of a novel human REG family gene, REG III K Nata, Y Liu, L Xu, T Ikeda, T Akiyama, N Noguchi, S Kawaguchi, ... Gene 340 (1), 161-170, 2004 | 107 | 2004 |
| A missense mutation in the CD38 gene, a novel factor for insulin secretion: association with Type II diabetes mellitus in Japanese subjects and evidence of abnormal function … K Yagui, F Shimada, M Mimura, N Hashimoto, Y Suzuki, Y Tokuyama, ... Diabetologia 41, 1024-1028, 1998 | 103 | 1998 |
| Cyclin D1 activation through ATF-2 in Reg-induced pancreatic β-cell regeneration S Takasawa, T Ikeda, T Akiyama, K Nata, K Nakagawa, NJ Shervani, ... FEBS letters 580 (2), 585-591, 2006 | 96 | 2006 |
| Lysine 129 of CD38 (ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase) participates in the binding of ATP to inhibit the cyclic ADP-ribose hydrolase A Tohgo, H Munakata, S Takasawa, K Nata, T Akiyama, N Hayashi, ... Journal of Biological Chemistry 272 (7), 3879-3882, 1997 | 80 | 1997 |
| Assignment of CD38, the gene encoding human leukocyte antigen CD38 (ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase), to chromosome 4p15 K Nakagawara, M Mori, S Takasawa, K Nata, T Takamura, A Berlova, ... Cytogenetic and Genome Research 69 (1-2), 38-39, 1995 | 73 | 1995 |
| The CD38-cyclic ADP-ribose signalling system in insulin secretion: molecular basis and clinical implications H Okamoto, S Takasawa, K Nata Diabetologia 40 (12), 1485-1491, 1997 | 69 | 1997 |
