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Nikita Sharma, PhD. MS
Nikita Sharma, PhD. MS
在 boehringer-ingelheim.com 的电子邮件经过验证
标题
引用次数
引用次数
年份
Targeting tumor-intrinsic hexosamine biosynthesis sensitizes pancreatic cancer to anti-PD1 therapy
NS Sharma, VK Gupta, VT Garrido, R Hadad, BC Durden, K Kesh, B Giri, ...
The Journal of clinical investigation 130 (1), 451-465, 2020
1782020
Inactivation of cancer-associated-fibroblasts disrupts oncogenic signaling in pancreatic cancer cells and promotes its regression
P Dauer, X Zhao, VK Gupta, N Sharma, K Kesh, P Gnamlin, V Dudeja, ...
Cancer research 78 (5), 1321-1333, 2018
1252018
ER stress sensor, glucose regulatory protein 78 (GRP78) regulates redox status in pancreatic cancer thereby maintaining “stemness”
P Dauer, NS Sharma, VK Gupta, B Durden, R Hadad, S Banerjee, ...
Cell death & disease 10 (2), 132, 2019
1062019
O-GlcNAc modification of Sox2 regulates self-renewal in pancreatic cancer by promoting its stability
NS Sharma, VK Gupta, P Dauer, K Kesh, R Hadad, B Giri, A Chandra, ...
Theranostics 9 (12), 3410, 2019
652019
Hypoxia-driven oncometabolite L-2HG maintains stemness-differentiation balance and facilitates immune evasion in pancreatic cancer
VK Gupta, NS Sharma, B Durden, VT Garrido, K Kesh, D Edwards, ...
Cancer research 81 (15), 4001-4013, 2021
612021
Metastasis and chemoresistance in CD133 expressing pancreatic cancer cells are dependent on their lipid raft integrity
VK Gupta, NS Sharma, K Kesh, P Dauer, A Nomura, B Giri, V Dudeja, ...
Cancer letters 439, 101-112, 2018
582018
NFκB-Mediated Invasiveness in CD133+ Pancreatic TICs Is Regulated by Autocrine and Paracrine Activation of IL1 Signaling.
BS Nomura A1,2, Gupta VK1, Dauer P1,3, Sharma NS1,4, Dudeja V1, Merchant N1 ...
Molecular Cancer Research, 2018
582018
GRP 78‐mediated antioxidant response and ABC transporter activity confers chemoresistance to pancreatic cancer cells
P Dauer, NS Sharma, VK Gupta, A Nomura, V Dudeja, A Saluja, ...
Molecular oncology 12 (9), 1498-1512, 2018
482018
Inhibition of hypoxic response decreases stemness and reduces tumorigenic signaling due to impaired assembly of HIF1 transcription complex in pancreatic cancer
O McGinn, VK Gupta, P Dauer, N Arora, N Sharma, A Nomura, V Dudeja, ...
Scientific reports 7 (1), 7872, 2017
402017
Inhibition of Sp1 prevents ER homeostasis and causes cell death by lysosomal membrane permeabilization in pancreatic cancer
P Dauer, VK Gupta, O McGinn, A Nomura, NS Sharma, N Arora, B Giri, ...
Scientific reports 7 (1), 1564, 2017
372017
Stroma secreted IL6 selects for “stem-like” population and alters pancreatic tumor microenvironment by reprogramming metabolic pathways
ASSB Kousik Kesh, Vanessa T. Garrido, Austin Dosch, Brittany Durden, Vineet ...
Cell Death and Disease 11, 2020
322020
“Nutrient-sensing” and self-renewal: O-GlcNAc in a new role
NS Sharma, AK Saluja, S Banerjee
Journal of bioenergetics and biomembranes 50, 205-211, 2018
302018
Long non-coding RNA GAS5 acts as proliferation "brakes" in CD133+ cells responsible for tumor recurrence
SB NS Sharma, P Gnamlin,B Durden, VK Gupta, K Kesh, VT Garrido,V Dudeja,A Saluja
Oncogenesis 8 (68), 2019
252019
Oncolytic Adenoviruses: Strategies for Improved Targeting and Specificity
MY Praveensingh B Hajeri, Nikita S Sharma
Cancers, 2020
232020
Minnelide synergizes with conventional chemotherapy by targeting both cancer and associated stroma components in pancreatic cancer
AKS Shrey Modi, Bhuwan Giri, Vineet K. Gupta, Shweta Lavania, Vrishketan ...
Cancer Letters, 2022
162022
O-GlcNAc modification of oncogenic transcription factor Sox2 promotes protein stability and regulates self-renewal in pancreatic cancer
NS Sharma, VK Gupta, P Dauer, K Kesh, R Hadad, B Giri, A Chandra, ...
bioRxiv, 345223, 2018
82018
Split-belt walking: An experience that is hard to forget
TJW Buurke, N Sharma, SB Swart, LHV van der Woude, R den Otter, ...
Gait & Posture 97, 184-187, 2022
62022
Interferon‐expressing oncolytic adenovirus+ chemoradiation inhibited pancreatic cancer growth in a hamster model
S Shinoda, NS Sharma, N Nakamura, K Inoko, M Sato‐Dahlman, ...
Cancer Science 114 (9), 3759-3769, 2023
32023
939 Autocrine/paracrine factors in cancer associated fibroblasts drive immunosuppression through impaired myeloid cell functions
N Sharma, P Govindaraju, S Bradford, Y Wang, B Flynn, CWS Lei, ...
Journal for Immunotherapy of Cancer 9 (Suppl 2), A985-A985, 2021
12021
Hypoxia-driven oncometabolite L-2HG maintains “stemness”-differentiation balance and facilitates immune suppression in pancreatic cancer
VK Gupta, NS Sharma, B Durden, VT Garrido, K Kesh, D Edwards, ...
bioRxiv, 2020.05. 08.084244, 2020
12020
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