| Functional constraints of influenza A virus epitopes limit escape from cytotoxic T lymphocytes EGM Berkhoff, E De Wit, MM Geelhoed-Mieras, ACM Boon, J Symons, ... Journal of virology 79 (17), 11239-11246, 2005 | 121 | 2005 |
| HIV integration sites in latently infected cell lines: evidence of ongoing replication J Symons, A Chopra, E Malatinkova, W De Spiegelaere, S Leary, ... Retrovirology 14, 1-11, 2017 | 87 | 2017 |
| In Vivo T Cell-Targeting Nanoparticle Drug Delivery Systems: Considerations for Rational Design PM Cevaal, A Ali, E Czuba-Wojnilowicz, J Symons, SR Lewin, ... ACS nano 15 (3), 3736-3753, 2021 | 67 | 2021 |
| Reprogrammed CRISPR-Cas13b suppresses SARS-CoV-2 replication and circumvents its mutational escape through mismatch tolerance M Fareh, W Zhao, W Hu, JML Casan, A Kumar, J Symons, JM Zerbato, ... Nature communications 12 (1), 4270, 2021 | 63 | 2021 |
| Dependence on the CCR5 coreceptor for viral replication explains the lack of rebound of CXCR4-predicted HIV variants in the Berlin patient J Symons, L Vandekerckhove, G Hütter, AMJ Wensing, PM van Ham, ... Clinical Infectious Diseases 59 (4), 596-600, 2014 | 57 | 2014 |
| Fitness costs limit escape from cytotoxic T lymphocytes by influenza A viruses EGM Berkhoff, E de Wit, MM Geelhoed-Mieras, ACM Boon, J Symons, ... Vaccine 24 (44-46), 6594-6596, 2006 | 57 | 2006 |
| Efficacy and safety of an attenuated live QX-like infectious bronchitis virus strain as a vaccine for chickens HJ Geerligs, GJ Boelm, CAM Meinders, BGE Stuurman, J Symons, ... Avian pathology 40 (1), 93-102, 2011 | 52 | 2011 |
| HIV integration sites and implications for maintenance of the reservoir J Symons, PU Cameron, SR Lewin Current Opinion in HIV and AIDS 13 (2), 152-159, 2018 | 45 | 2018 |
| HIV population genotypic tropism testing and its clinical significance M Obermeier, J Symons, AMJ Wensing Current Opinion in HIV and AIDS 7 (5), 470-477, 2012 | 44 | 2012 |
| Impact of triplicate testing on HIV genotypic tropism prediction in routine clinical practice J Symons, L Vandekerckhove, R Paredes, C Verhofstede, R Bellido, ... Clinical microbiology and infection 18 (6), 606-612, 2012 | 41 | 2012 |
| Maraviroc intensification of cART in patients with suboptimal immunological recovery: a 48-week, placebo-controlled randomized trial SFL van Lelyveld, J Drylewicz, M Krikke, EM Veel, SA Otto, C Richter, ... PLoS One 10 (7), e0132430, 2015 | 39 | 2015 |
| Relationship between CD4 T cell turnover, cellular differentiation and HIV persistence during ART C Bacchus-Souffan, M Fitch, J Symons, M Abdel-Mohsen, DB Reeves, ... PLoS pathogens 17 (1), e1009214, 2021 | 37 | 2021 |
| Maraviroc is able to inhibit dual-R5 viruses in a dual/mixed HIV-1-infected patient J Symons, SFL Van Lelyveld, AIM Hoepelman, PM Van Ham, D De Jong, ... Journal of antimicrobial chemotherapy 66 (4), 890-895, 2011 | 36 | 2011 |
| HIV-1 reverse transcriptase connection domain mutations: dynamics of emergence and implications for success of combination antiretroviral therapy V von Wyl, M Ehteshami, LM Demeter, P Bürgisser, M Nijhuis, J Symons, ... Clinical infectious diseases 51 (5), 620-628, 2010 | 35 | 2010 |
| Epidemiological and biological evidence for a compensatory effect of connection domain mutation N348I on M184V in HIV-1 reverse transcriptase V von Wyl, M Ehteshami, J Symons, P Bürgisser, M Nijhuis, LM Demeter, ... The Journal of infectious diseases 201 (7), 1054-1062, 2010 | 33 | 2010 |
| CXCR4-Using HIV Strains Predominate in Naive and Central Memory CD4+ T Cells in People Living with HIV on Antiretroviral Therapy: Implications for How … M Roche, C Tumpach, J Symons, M Gartner, JL Anderson, G Khoury, ... Journal of virology 94 (6), 10.1128/jvi. 01736-19, 2020 | 28 | 2020 |
| Acoustofection: high-frequency vibrational membrane permeabilization for intracellular siRNA delivery into nonadherent cells S Ramesan, AR Rezk, PM Cevaal, C Cortez-Jugo, J Symons, LY Yeo ACS Applied Bio Materials 4 (3), 2781-2789, 2021 | 27 | 2021 |
| Improved single-chain transactivators of the Tet-On gene expression system X Zhou, J Symons, R Hoppes, C Krueger, C Berens, W Hillen, B Berkhout, ... BMC biotechnology 7, 1-9, 2007 | 24 | 2007 |
| Shock and kill within the CNS: A promising HIV eradication approach? MM Nühn, SBH Gumbs, NVEJ Buchholtz, LM Jannink, L Gharu, ... Journal of Leukocyte Biology 112 (5), 1297-1315, 2022 | 13 | 2022 |
| Maraviroc treatment in non-R5-HIV-1-infected patients results in the selection of extreme CXCR4-using variants with limited effect on the total viral setpoint RA McGovern, J Symons, AFY Poon, PR Harrigan, SFL van Lelyveld, ... Journal of Antimicrobial Chemotherapy 68 (9), 2007-2014, 2013 | 13 | 2013 |
