Anle138b: a novel oligomer modulator for disease-modifying therapy of neurodegenerative diseases such as prion and Parkinson’s disease J Wagner, S Ryazanov, A Leonov, J Levin, S Shi, F Schmidt, C Prix, ... Acta neuropathologica 125, 795-813, 2013 | 428 | 2013 |
Lentivector-mediated RNAi efficiently suppresses prion protein and prolongs survival of scrapie-infected mice A Pfeifer, S Eigenbrod, S Al-Khadra, A Hofmann, G Mitteregger, M Moser, ... The Journal of clinical investigation 116 (12), 3204-3210, 2006 | 207 | 2006 |
Effect of metal ions on de novo aggregation of full-length prion protein A Giese, J Levin, U Bertsch, H Kretzschmar Biochemical and biophysical research communications 320 (4), 1240-1246, 2004 | 133 | 2004 |
Identification, characterization, and DNA sequence of a functional" double" groES-like chaperonin from chloroplasts of higher plants. U Bertsch, J Soll, R Seetharam, PV Viitanen Proceedings of the National Academy of Sciences 89 (18), 8696-8700, 1992 | 133 | 1992 |
Nuclear death receptor TRAIL-R2 inhibits maturation of let-7 and promotes proliferation of pancreatic and other tumor cells V Haselmann, A Kurz, U Bertsch, S Hübner, M Olempska–Müller, J Fritsch, ... Gastroenterology 146 (1), 278-290, 2014 | 131 | 2014 |
Caspase‐8 and caspase‐7 sequentially mediate proteolytic activation of acid sphingomyelinase in TNF‐R1 receptosomes B Edelmann, U Bertsch, V Tchikov, S Winoto‐Morbach, C Perrotta, ... The EMBO journal 30 (2), 379-394, 2011 | 123 | 2011 |
Systematic identification of antiprion drugs by high-throughput screening based on scanning for intensely fluorescent targets U Bertsch, KF Winklhofer, T Hirschberger, J Bieschke, P Weber, FU Hartl, ... Journal of virology 79 (12), 7785-7791, 2005 | 115 | 2005 |
TRAIL signaling is mediated by DR4 in pancreatic tumor cells despite the expression of functional DR5 J Lemke, A Noack, D Adam, V Tchikov, U Bertsch, C Röder, S Schütze, ... Journal of Molecular Medicine 88, 729-740, 2010 | 109 | 2010 |
A plant homologue to mammalian brain 14-3-3 protein and protein kinase C inhibitor S Hirsch, A Aitken, U Bertsch, J Soll FEBS letters 296 (2), 222-224, 1992 | 104 | 1992 |
Modulation of CD4+ T-cell activation by CD95 co-stimulation M Paulsen, S Valentin, B Mathew, S Adam-Klages, U Bertsch, I Lavrik, ... Cell Death & Differentiation 18 (4), 619-631, 2011 | 74 | 2011 |
Compartmentalization of TNF-related apoptosis-inducing ligand (TRAIL) death receptor functions: emerging role of nuclear TRAIL-R2 U Bertsch, C Röder, H Kalthoff, A Trauzold Cell death & disease 5 (8), e1390-e1390, 2014 | 72 | 2014 |
Spinach chloroplast cpn21 co-chaperonin possesses two functional domains fused together in a toroidal structure and exhibits nucleotide-dependent binding to plastid chaperonin 60 F Baneyx, U Bertsch, CE Kalbach, SM van der Vies, J Soll, AA Gatenby Journal of Biological Chemistry 270 (18), 10695-10702, 1995 | 72 | 1995 |
Subcellular compartmentalization of TNF receptor-1 and CD95 signaling pathways V Tchikov, U Bertsch, J Fritsch, B Edelmann, S Schütze European journal of cell biology 90 (6-7), 467-475, 2011 | 70 | 2011 |
Conversion efficiency of bank vole prion protein in vitro is determined by residues 155 and 170, but does not correlate with the high susceptibility of bank voles to sheep … N Piening, R Nonno, M Di Bari, S Walter, O Windl, U Agrimi, ... Journal of Biological Chemistry 281 (14), 9373-9384, 2006 | 70 | 2006 |
Single particle analysis of manganese-induced prion protein aggregates J Levin, U Bertsch, H Kretzschmar, A Giese Biochemical and biophysical research communications 329 (4), 1200-1207, 2005 | 68 | 2005 |
Toward semisynthetic lipoproteins by convergent strategies based on click and ligation chemistry HJ Musiol, S Dong, M Kaiser, R Bausinger, A Zumbusch, U Bertsch, ... ChemBioChem 6 (4), 625-628, 2005 | 53 | 2005 |
Novel G335V mutation in the tau gene associated with early onset familial frontotemporal dementia M Neumann, S Diekmann, U Bertsch, B Vanmassenhove, B Bogerts, ... Neurogenetics 6, 91-95, 2005 | 51 | 2005 |
A new method to determine the structure of the metal environment in metalloproteins: investigation of the prion protein octapeptide repeat Cu2+ complex M Mentler, A Weiss, K Grantner, P Del Pino, D Deluca, S Fiori, C Renner, ... European Biophysics Journal 34, 97-112, 2005 | 46 | 2005 |
Rat inositol 1, 4, 5-trisphosphate 3-kinase C is enzymatically specialized for basal cellular inositol trisphosphate phosphorylation and shuttles actively between nucleus and … MM Nalaskowski, U Bertsch, W Fanick, MC Stockebrand, H Schmale, ... Journal of Biological Chemistry 278 (22), 19765-19776, 2003 | 46 | 2003 |
The configuration of the Cu2+ binding region in full-length human prion protein P Del Pino, A Weiss, U Bertsch, C Renner, M Mentler, K Grantner, ... European Biophysics Journal 36, 239-252, 2007 | 37 | 2007 |